Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038260032> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2038260032 endingPage "184" @default.
- W2038260032 startingPage "181" @default.
- W2038260032 abstract "In 1976 Ehrly and co-workers as well as Reid and co-workers investigated the filterability of blood from patients with chronic occlusive vascular diseases. Using micropore filters there was a markedly reduced filterability in spite of differences in the filterability techniques as filter type, hydrostatic pressure and others.The results were explained by an increased ridgidity of red cells which increase the resistance to flow through the filter pores. These findings where discussed as one of the pathophysiological mechanisms of chronic occlusive arterial diseases, but brought up a number of questions such as the mechanism of the reduced filterability and the significance of an impaired deformability of red cells in vivo. Another question is if the impaired filterability of blood is the cause or the consequence of the underlying disease.If we consider the red cell deformability to be an important factor for the pathophysiology of vascular diseases, it seems clear that not only the mechanical property of the less deformable red cell in the capillary will be most important, but also rigid red cell as a cause for an inhomogenous blood flow in the microcirculation (microcirculatory blood maldistribution).From the therapeutic point of view it seems important to know the mechanism which leads to an impaired flexibility of red cells, so, for example, a low ATP-content in the cells, hypermolarity or acidosis of blood.In vitro tests, like filtration of patients blood through micropore filters, may indicate the value of drugs said to improve the deformability of red cells. More sophisticated methods like the measurement of the oxygen tension of the muscle tissue can give us an answer as to whether an improvement of the deformability of red cells also leads to an improvement of the tissue supply." @default.
- W2038260032 created "2016-06-24" @default.
- W2038260032 creator A5012680676 @default.
- W2038260032 creator A5050306876 @default.
- W2038260032 date "1981-01-01" @default.
- W2038260032 modified "2023-10-05" @default.
- W2038260032 title "Red blood cell filterability and occlusive arterial disease" @default.
- W2038260032 cites W2418098983 @default.
- W2038260032 doi "https://doi.org/10.3109/00365518109097456" @default.
- W2038260032 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6948382" @default.
- W2038260032 hasPublicationYear "1981" @default.
- W2038260032 type Work @default.
- W2038260032 sameAs 2038260032 @default.
- W2038260032 citedByCount "12" @default.
- W2038260032 crossrefType "journal-article" @default.
- W2038260032 hasAuthorship W2038260032A5012680676 @default.
- W2038260032 hasAuthorship W2038260032A5050306876 @default.
- W2038260032 hasConcept C10162356 @default.
- W2038260032 hasConcept C105795698 @default.
- W2038260032 hasConcept C126322002 @default.
- W2038260032 hasConcept C12722491 @default.
- W2038260032 hasConcept C128489963 @default.
- W2038260032 hasConcept C158846371 @default.
- W2038260032 hasConcept C164705383 @default.
- W2038260032 hasConcept C2776557347 @default.
- W2038260032 hasConcept C2777208419 @default.
- W2038260032 hasConcept C33923547 @default.
- W2038260032 hasConcept C71924100 @default.
- W2038260032 hasConceptScore W2038260032C10162356 @default.
- W2038260032 hasConceptScore W2038260032C105795698 @default.
- W2038260032 hasConceptScore W2038260032C126322002 @default.
- W2038260032 hasConceptScore W2038260032C12722491 @default.
- W2038260032 hasConceptScore W2038260032C128489963 @default.
- W2038260032 hasConceptScore W2038260032C158846371 @default.
- W2038260032 hasConceptScore W2038260032C164705383 @default.
- W2038260032 hasConceptScore W2038260032C2776557347 @default.
- W2038260032 hasConceptScore W2038260032C2777208419 @default.
- W2038260032 hasConceptScore W2038260032C33923547 @default.
- W2038260032 hasConceptScore W2038260032C71924100 @default.
- W2038260032 hasIssue "sup156" @default.
- W2038260032 hasLocation W20382600321 @default.
- W2038260032 hasLocation W20382600322 @default.
- W2038260032 hasOpenAccess W2038260032 @default.
- W2038260032 hasPrimaryLocation W20382600321 @default.
- W2038260032 hasRelatedWork W2033424694 @default.
- W2038260032 hasRelatedWork W2092523531 @default.
- W2038260032 hasRelatedWork W2098540373 @default.
- W2038260032 hasRelatedWork W2401302815 @default.
- W2038260032 hasRelatedWork W2460061332 @default.
- W2038260032 hasRelatedWork W2473262624 @default.
- W2038260032 hasRelatedWork W2547725650 @default.
- W2038260032 hasRelatedWork W3009422881 @default.
- W2038260032 hasRelatedWork W4231779086 @default.
- W2038260032 hasRelatedWork W55094341 @default.
- W2038260032 hasVolume "41" @default.
- W2038260032 isParatext "false" @default.
- W2038260032 isRetracted "false" @default.
- W2038260032 magId "2038260032" @default.
- W2038260032 workType "article" @default.