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- W2038289293 abstract "Abstract The serotonin syndrome is an increasingly recognised clinical condition characterised by a triad of motor, mental status and autonomic changes. In most cases it is mild and self limiting. In severe cases it can progress to rhabdomyolysis, disseminated intravascular coagulation and death. The syndrome is caused by an increased level of serotonin in the central nervous system. This is usually the result of the administration of combinations of serotinergic agents. This article describes two cases of the syndrome where the diagnosis was not immediately apparent. The pathophysiology, clinical course and treatment are then discussed. Serotonin syndrome is also compared to neuroleptic malignant syndrome. This is a disorder with similar signs and symptoms and may have a similar pathophysiological basis. Serotinergic agents are commonly prescribed. Emergency physicians must be vigilant for this easily overlooked, potentially fatal but treatable disorder." @default.
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- W2038289293 date "1997-09-01" @default.
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- W2038289293 title "The serotonin syndrome" @default.
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- W2038289293 doi "https://doi.org/10.1111/j.1442-2026.1997.tb00388.x" @default.
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