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- W2038319889 abstract "Thermal therapy has the potential to provide a nonexcisional alternative to tonsillectomy. Clinical implementationrequires that the lymphoid tissue of tonsils is heated homogeneously to produce an amount of primary thermal injury thatcorresponds to gradual postoperative tonsil shrinkage, with minimal risk of damage to underlying critical blood vessels.Optical constants are derived for tonsils from tissue components and used to calculate the depth of 1/e of irradiance. The1125 nm wavelength is shown to correspond to both deep penetration and minimal absorption by blood. A probe fortonsil thermal therapy that comprises two opposing light emitting, temperature controlled surfaces is described. For exvivo characterization of tonsil heating, a prototype 1125 nm diode laser is used in an experimental apparatus that splitsthe laser output into two components, and delivers the radiation to sapphire contact window surfaces of two temperaturecontrolled cells arranged to irradiate human tonsil specimens from opposing directions. Temperatures are measured withthermocouple microprobes at located points within the tissue during and after irradiation. Primary thermal damagecorresponding to the recorded thermal histories are calculated from Arrhenius parameters for human tonsils. Resultsindicate homogeneous heating to temperatures corresponding to the threshold of thermal injury and above can beachieved in advantageously short irradiation times." @default.
- W2038319889 created "2016-06-24" @default.
- W2038319889 creator A5010229034 @default.
- W2038319889 date "2011-02-10" @default.
- W2038319889 modified "2023-09-23" @default.
- W2038319889 title "1125-nm quantum dot laser for tonsil thermal therapy" @default.
- W2038319889 doi "https://doi.org/10.1117/12.876321" @default.
- W2038319889 hasPublicationYear "2011" @default.
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