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- W2038376496 abstract "Literature data indicate a reduced calcium uptake in synaptosomes prepared from old rat brains. On this line, the present paper investigates the binding of ([3H]NDP) to brain synaptic membranes prepared from rats at different ages from birth up to 24 months of age. The binding is undetectable at birth but reaches within 9-18 day the values observed in adults [3H]NDP binding affinity and sensitivity to calcium were decreased in old rats (24 months). Tritiated dihydropyridines are believed to label voltage-dependent calcium channels (VDC). The observed age-related reduction in binding suggests that the characteristics of VDC in the aged brain may change." @default.
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- W2038376496 date "1985-05-01" @default.
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- W2038376496 title "Age-related reduced affinity in [3H]nitrendipine labeling of brain voltage-dependent calcium channels" @default.
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- W2038376496 doi "https://doi.org/10.1016/0006-8993(85)91596-3" @default.
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