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- W2038387804 abstract "Abstract 1. 1. Rats were injected with d,l; 1- or d-propranolol, 50 mg/kg i.p. 2. 2. Levels of the monoamine metabolites 3-methoxy-4-hydroxyphenylglycol (MOPEG), homovanillic acid (HVA) and 5-hydroxy-indole-3-acetic acid (5-HIAA) were determined by mass fragmentography in regions of rat brain. 3. 3. After d,l; and 1-propranolol the MOPEG content in brain increased significantly. The HVA level was preferentially increased in a limbic brain region, the olfactory tubercle. The 5-HIAA content was diminished or unchanged irrespective of the isomeric forms of propranolol. 4. 4. The elevated levels of MOPEG and HVA after l-propranolol may be of relevance for the antipsychotic properties suggested for d,l-propranolol." @default.
- W2038387804 created "2016-06-24" @default.
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- W2038387804 date "1977-01-01" @default.
- W2038387804 modified "2023-09-30" @default.
- W2038387804 title "Effects of the isomeric forms of propranolol on central monoamine metabolism in regions of rat brain" @default.
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- W2038387804 doi "https://doi.org/10.1016/0364-7722(77)90029-7" @default.
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