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- W2038422731 abstract "Blood pressure and pulse were monitored throughout 24 hours in 13 middle-aged men using a sphygmomanometer with an automatically inflatable cuff. These volunteers were in part mistakenly believed to have a mildly elevated blood pressure (in the light of a conventional non-chronobiologic approach, involving time-unspecified spot checks of blood pressure). Within about 24 hours, blood pressures and pulse varied remarkably: the coefficient of variation extended from 6.9 to 14.9% for systolic blood pressure (SBP), from 8.5 to 15.4% for diastolic blood pressure (DBP) and from 8.0 to 17.9% for pulse. By applying the single cosinor method (involving the least-squares fit of a 24-hour cosine curve), statistically significant circadian rhythms were observed in SBP, DBP, and pulse in all but 2 cases. In most cases, the timing of peak values was estimated to be in the evening for all 3 variables. Circadian rhythmicity accounted for up to 46, 30, and 42% of the total variability of SBP, DBP, and pulse, respectively. This marked circadian rhythmic variability is an important aspect of cardiovascular function." @default.
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- W2038422731 date "1982-01-01" @default.
- W2038422731 modified "2023-09-23" @default.
- W2038422731 title "Chronopsies assess the within-day variability of blood pressure and pulse." @default.
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- W2038422731 doi "https://doi.org/10.1536/ihj.23.661" @default.
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