FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038471403> ?p ?o ?g. }

• W2038471403 endingPage "6322" @default.
• W2038471403 startingPage "6318" @default.
• W2038471403 abstract "The protein kinase C activator phorbol 12-myristate 13-acetate (PMA) induces rapid and reversible shape changes in cultured fibroblasts: extension of motile lamellas is followed by transformation of these lamellas into nonmotile stalklike processes. This lamella-to-stalk transformation was found to be associated with the formation of microtubules enriched in detyrosinated alpha-tubulin. This change was local: microtubules in motile lamellas at the distal ends of the processes and in the cell bodies were not enriched in detyrosinated alpha-tubulin. Detyrosinated microtubules in the processes were more resistant to Colcemid treatment than other microtubules of PMA-treated and control cells. The effects of PMA were reversible and could be abolished by sphingosine, a specific inhibitor of protein kinase C. Besides modification of microtubules, lamella-to-stalk transformation is associated with the ingrowth of intermediate filaments into the extensions. Earlier it was found that this transformation is also associated with the profound reorganization of the system of actin microfilaments. Thus, all three cytoskeletal systems are altered simultaneously during PMA-induced formation of processes. Similar cytoskeletal synergies may play essential roles in many morphogenetic processes--e.g., in the growth of neurites." @default.
• W2038471403 created "2016-06-24" @default.
• W2038471403 creator A5051489938 @default.
• W2038471403 creator A5054582362 @default.
• W2038471403 creator A5067297874 @default.
• W2038471403 creator A5091065680 @default.
• W2038471403 date "1991-07-15" @default.
• W2038471403 modified "2023-09-26" @default.
• W2038471403 title "Post-translational modification of microtubules is a component of synergic alterations of cytoskeleton leading to formation of cytoplasmic processes in fibroblasts." @default.
• W2038471403 cites W1573751470 @default.
• W2038471403 cites W1590154399 @default.
• W2038471403 cites W1626096776 @default.
• W2038471403 cites W1817417297 @default.
• W2038471403 cites W1963990357 @default.
• W2038471403 cites W1967296853 @default.
• W2038471403 cites W1975836015 @default.
• W2038471403 cites W1979993594 @default.
• W2038471403 cites W1985476658 @default.
• W2038471403 cites W2001692359 @default.
• W2038471403 cites W2004813178 @default.
• W2038471403 cites W2009765924 @default.
• W2038471403 cites W2012136237 @default.
• W2038471403 cites W2018133064 @default.
• W2038471403 cites W2024815270 @default.
• W2038471403 cites W2036026294 @default.
• W2038471403 cites W2050998289 @default.
• W2038471403 cites W2054391977 @default.
• W2038471403 cites W2057699135 @default.
• W2038471403 cites W2059667498 @default.
• W2038471403 cites W2061574494 @default.
• W2038471403 cites W2063029126 @default.
• W2038471403 cites W2077043119 @default.
• W2038471403 cites W2078397176 @default.
• W2038471403 cites W2094388738 @default.
• W2038471403 cites W2116170706 @default.
• W2038471403 cites W2133128874 @default.
• W2038471403 cites W2144420983 @default.
• W2038471403 cites W2148327308 @default.
• W2038471403 doi "https://doi.org/10.1073/pnas.88.14.6318" @default.
• W2038471403 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/52074" @default.
• W2038471403 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2068111" @default.
• W2038471403 hasPublicationYear "1991" @default.
• W2038471403 type Work @default.
• W2038471403 sameAs 2038471403 @default.
• W2038471403 citedByCount "16" @default.
• W2038471403 countsByYear W20384714032016 @default.
• W2038471403 countsByYear W20384714032022 @default.
• W2038471403 crossrefType "journal-article" @default.
• W2038471403 hasAuthorship W2038471403A5051489938 @default.
• W2038471403 hasAuthorship W2038471403A5054582362 @default.
• W2038471403 hasAuthorship W2038471403A5067297874 @default.
• W2038471403 hasAuthorship W2038471403A5091065680 @default.
• W2038471403 hasBestOaLocation W20384714032 @default.
• W2038471403 hasConcept C105702510 @default.
• W2038471403 hasConcept C125705527 @default.
• W2038471403 hasConcept C136301237 @default.
• W2038471403 hasConcept C142669718 @default.
• W2038471403 hasConcept C1491633281 @default.
• W2038471403 hasConcept C170493617 @default.
• W2038471403 hasConcept C189040839 @default.
• W2038471403 hasConcept C190062978 @default.
• W2038471403 hasConcept C20418707 @default.
• W2038471403 hasConcept C2776095844 @default.
• W2038471403 hasConcept C55493867 @default.
• W2038471403 hasConcept C84425145 @default.
• W2038471403 hasConcept C86803240 @default.
• W2038471403 hasConcept C88045685 @default.
• W2038471403 hasConcept C95444343 @default.
• W2038471403 hasConceptScore W2038471403C105702510 @default.
• W2038471403 hasConceptScore W2038471403C125705527 @default.
• W2038471403 hasConceptScore W2038471403C136301237 @default.
• W2038471403 hasConceptScore W2038471403C142669718 @default.
• W2038471403 hasConceptScore W2038471403C1491633281 @default.
• W2038471403 hasConceptScore W2038471403C170493617 @default.
• W2038471403 hasConceptScore W2038471403C189040839 @default.
• W2038471403 hasConceptScore W2038471403C190062978 @default.
• W2038471403 hasConceptScore W2038471403C20418707 @default.
• W2038471403 hasConceptScore W2038471403C2776095844 @default.
• W2038471403 hasConceptScore W2038471403C55493867 @default.
• W2038471403 hasConceptScore W2038471403C84425145 @default.
• W2038471403 hasConceptScore W2038471403C86803240 @default.
• W2038471403 hasConceptScore W2038471403C88045685 @default.
• W2038471403 hasConceptScore W2038471403C95444343 @default.
• W2038471403 hasIssue "14" @default.
• W2038471403 hasLocation W20384714031 @default.
• W2038471403 hasLocation W20384714032 @default.
• W2038471403 hasLocation W20384714033 @default.
• W2038471403 hasLocation W20384714034 @default.
• W2038471403 hasOpenAccess W2038471403 @default.
• W2038471403 hasPrimaryLocation W20384714031 @default.
• W2038471403 hasRelatedWork W1531816097 @default.
• W2038471403 hasRelatedWork W1594559229 @default.
• W2038471403 hasRelatedWork W1985476658 @default.
• W2038471403 hasRelatedWork W1999411716 @default.
• W2038471403 hasRelatedWork W2007117627 @default.
• W2038471403 hasRelatedWork W2038471403 @default.
• W2038471403 hasRelatedWork W2081451190 @default.
• W2038471403 hasRelatedWork W2154846674 @default.

• next