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- W2038480528 abstract "To the Editor:— The text of the editorial inThe Journal( 150 :1016 [Nov. 8] 1952) entitled Smoking and the Cardiovascular System constitutes a restrained and thoughtful approach to a difficult problem. Nevertheless, as in many similar analyses of the literature, an important physiological principle has been overlooked; i. e., the most potent stimulus to the formation of anastomotic vascular channels is ischemia. This has been repeatedly demonstrated experimentally and clinically. Consequently, one must give serious consideration to the possibility that smoking tobacco, through a vasoconstricting effect, might, over a period of time, actually serve as a stimulus to the formation of a greater functional vascular bed. The current policy of restricting the use of tobacco for the person with coronary or peripheral vascular disease may have an unphysiological basis, since the patient may be being denied the means of effectively withstanding a sudden major occlusion. A second although probably" @default.
- W2038480528 created "2016-06-24" @default.
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- W2038480528 date "1953-04-04" @default.
- W2038480528 modified "2023-09-24" @default.
- W2038480528 title "SMOKING AND THE CARDIOVASCULAR SYSTEM" @default.
- W2038480528 doi "https://doi.org/10.1001/jama.1953.02940140068026" @default.
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