Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038491674> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2038491674 endingPage "461" @default.
- W2038491674 startingPage "452" @default.
- W2038491674 abstract "Malignant Hyperthermia (MH) is a rare genetic disease. However, it is devastating when it occurs in a patient. MH is usually triggered by inhalational anesthetics and/or depolarizing muscle relaxants. Public awareness of MH has increased with the presentation of an episode on the television program, “House”, and the availability of web-based information. For over 20 years, the MH susceptible pig has been used in experiments by our group as an animal model for MH in humans. The incidence of Malignant Hyperthermia in the Greater Kansas City Area has declined dramatically since the introduction of Sevoflurane in 1992 as the anesthetic of choice (over 60% usage rate) in most surgical procedures. Historically, Malignant Hyperthermia was reported to occur at a rate of 1:50,000 during surgical procedures [1]. In the Greater Kansas City Area, Malignant Hyperthermia (MH) occurred at a rate of 1:53,636 during the 1965-1985 time period, as there were 38 MH cases in 35 patients [2]. During the past ten years (1996-2006), there were only 2 cases of MH, representing an incidence rate of 1:597,240. That decrease is an 11.13 fold (or 89%) decrease which is very significant. Despite the reduced incidence of Malignant Hyperthermia, two recent cases of MH that result in deaths in Wisconsin and Florida make it imperative that MH is recognized early and appropriate treatment initiated without delay. We have expanded our analysis of the futile cycle mechanism that underlies the MH syndrome. MH is equivalent to the rapid discharge of a battery by a short circuit." @default.
- W2038491674 created "2016-06-24" @default.
- W2038491674 creator A5020639888 @default.
- W2038491674 creator A5059423789 @default.
- W2038491674 creator A5089196941 @default.
- W2038491674 date "2014-01-01" @default.
- W2038491674 modified "2023-09-30" @default.
- W2038491674 title "A Review of the Factors Affecting the Incidence of Malignant Hyperthermia in the Greater Kansas City Area" @default.
- W2038491674 cites W185004022 @default.
- W2038491674 cites W2008109892 @default.
- W2038491674 cites W2008610963 @default.
- W2038491674 cites W2073753538 @default.
- W2038491674 cites W2082814731 @default.
- W2038491674 cites W2092133816 @default.
- W2038491674 cites W2094597903 @default.
- W2038491674 cites W2096920000 @default.
- W2038491674 cites W2333505089 @default.
- W2038491674 cites W2423922183 @default.
- W2038491674 cites W3161443624 @default.
- W2038491674 cites W596813253 @default.
- W2038491674 cites W2337226758 @default.
- W2038491674 doi "https://doi.org/10.4236/abb.2014.55055" @default.
- W2038491674 hasPublicationYear "2014" @default.
- W2038491674 type Work @default.
- W2038491674 sameAs 2038491674 @default.
- W2038491674 citedByCount "1" @default.
- W2038491674 countsByYear W20384916742015 @default.
- W2038491674 crossrefType "journal-article" @default.
- W2038491674 hasAuthorship W2038491674A5020639888 @default.
- W2038491674 hasAuthorship W2038491674A5059423789 @default.
- W2038491674 hasAuthorship W2038491674A5089196941 @default.
- W2038491674 hasBestOaLocation W20384916741 @default.
- W2038491674 hasConcept C120665830 @default.
- W2038491674 hasConcept C121332964 @default.
- W2038491674 hasConcept C126322002 @default.
- W2038491674 hasConcept C141071460 @default.
- W2038491674 hasConcept C2778575482 @default.
- W2038491674 hasConcept C2779949491 @default.
- W2038491674 hasConcept C42219234 @default.
- W2038491674 hasConcept C61511704 @default.
- W2038491674 hasConcept C71924100 @default.
- W2038491674 hasConceptScore W2038491674C120665830 @default.
- W2038491674 hasConceptScore W2038491674C121332964 @default.
- W2038491674 hasConceptScore W2038491674C126322002 @default.
- W2038491674 hasConceptScore W2038491674C141071460 @default.
- W2038491674 hasConceptScore W2038491674C2778575482 @default.
- W2038491674 hasConceptScore W2038491674C2779949491 @default.
- W2038491674 hasConceptScore W2038491674C42219234 @default.
- W2038491674 hasConceptScore W2038491674C61511704 @default.
- W2038491674 hasConceptScore W2038491674C71924100 @default.
- W2038491674 hasIssue "05" @default.
- W2038491674 hasLocation W20384916741 @default.
- W2038491674 hasOpenAccess W2038491674 @default.
- W2038491674 hasPrimaryLocation W20384916741 @default.
- W2038491674 hasRelatedWork W1571555654 @default.
- W2038491674 hasRelatedWork W174726926 @default.
- W2038491674 hasRelatedWork W1970518314 @default.
- W2038491674 hasRelatedWork W2008562123 @default.
- W2038491674 hasRelatedWork W2323614551 @default.
- W2038491674 hasRelatedWork W2404104792 @default.
- W2038491674 hasRelatedWork W2405909540 @default.
- W2038491674 hasRelatedWork W2406906648 @default.
- W2038491674 hasRelatedWork W2424599534 @default.
- W2038491674 hasRelatedWork W4249116296 @default.
- W2038491674 hasVolume "05" @default.
- W2038491674 isParatext "false" @default.
- W2038491674 isRetracted "false" @default.
- W2038491674 magId "2038491674" @default.
- W2038491674 workType "article" @default.