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- W2038527905 abstract "I N CLINICS such as our own where there is a considerable Negro population, the problem of differentiating between rheumatic heart disease and the cardiac manifestations of sickle cell anemia is often troublesome. Accurate distinction between the two diseases is important in deciding upon the proper management of the individual case. The literature on heart disturbances in sickle cell anemia was reviewed in 1942 by Klinefelter, I who added twelve eases of his own. Klinefelter pointed out certain peculiarities of the disorder which serve to distinguish it not only from rheumatic carditis, but also from the changes found in other forms of anemia. Wintrobe, 2 on the other hand. fee]s that the changes are similar to, if not identical with, those found in other chronic anemias. In relation to diagnosis, perhaps the most important of Klinefelter's conclusions is that rheumatic fever and sickle cell anemia do not coincide in the same patient. While he apparently overlooked Walker and Murphy's report '~ in which both conditions were found at autopsy, proved exceptions to the rule appear to be exceedingly rare. Nearly all reported cases of cardiopathy in sickle cell anemia have been in adults. In children, IIamman 4 reported a case in 1933, and King and Janeway 5 another in 1937. The following case is reported because of the apparent infrequency of the disorder in children and because it illustrates the diagnostic difficulties. CASE REPORT" @default.
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- W2038527905 date "1947-03-01" @default.
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- W2038527905 title "The cardiopathy of sickle cell anemia and itsdifferentiation from rheumatic carditis" @default.
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- W2038527905 doi "https://doi.org/10.1016/s0022-3476(47)80163-5" @default.
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