FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038536497> ?p ?o ?g. }

• W2038536497 endingPage "109" @default.
• W2038536497 startingPage "101" @default.
• W2038536497 abstract "Nucleotide excision repair (NER) removes a wide variety of helix distorting DNA lesions. NER comprises two damage recognition sub-pathways: GG-NER operates genome wide, whereas TC-NER specifically removes transcription-blocking lesions from the transcribed strand of actively transcribed genes. NER is a multistep process, which requires the concerted action of 30 proteins that need to be tightly controlled at the right time and place for efficient repair. Post-translational protein modifications (PTMs) are common regulators of complex protein networks. Several NER factors were shown to be modified by ubiquitin, whereas others are actively involved in the ubiquitin–proteasome system itself. PTMs by ubiquitylation can be swiftly induced in a reversible manner and have the ability to regulate protein function, localization or stability. This makes the regulation by ubiquitin highly suitable for the coordination of the complex NER reaction. Accumulating evidence, including proteome wide quantitative proteomics approaches, showed that especially NER factors involved in the damage recognition are regulated by ubiquitin, emphasizing the high level of regulation during the initiation of the NER reaction. In this review we will therefore focus on the different functions of ubiquitylation during the DNA damage recognition steps of NER." @default.
• W2038536497 created "2016-06-24" @default.
• W2038536497 creator A5023539579 @default.
• W2038536497 creator A5045629892 @default.
• W2038536497 creator A5065375123 @default.
• W2038536497 date "2014-11-01" @default.
• W2038536497 modified "2023-09-23" @default.
• W2038536497 title "Ubiquitin at work: The ubiquitous regulation of the damage recognition step of NER" @default.
• W2038536497 cites W1977982042 @default.
• W2038536497 cites W1978590712 @default.
• W2038536497 cites W1979417055 @default.
• W2038536497 cites W1980468156 @default.
• W2038536497 cites W1984225002 @default.
• W2038536497 cites W1984866675 @default.
• W2038536497 cites W1987211450 @default.
• W2038536497 cites W1989208996 @default.
• W2038536497 cites W1989643386 @default.
• W2038536497 cites W1989829234 @default.
• W2038536497 cites W1990963600 @default.
• W2038536497 cites W1991793156 @default.
• W2038536497 cites W1994300590 @default.
• W2038536497 cites W1996516839 @default.
• W2038536497 cites W2002900988 @default.
• W2038536497 cites W2006863188 @default.
• W2038536497 cites W2009890510 @default.
• W2038536497 cites W2016874507 @default.
• W2038536497 cites W2028884100 @default.
• W2038536497 cites W2032739040 @default.
• W2038536497 cites W2033734580 @default.
• W2038536497 cites W2037936898 @default.
• W2038536497 cites W2038038813 @default.
• W2038536497 cites W2038616578 @default.
• W2038536497 cites W2040498703 @default.
• W2038536497 cites W2046727880 @default.
• W2038536497 cites W2047350942 @default.
• W2038536497 cites W2053699468 @default.
• W2038536497 cites W2066554319 @default.
• W2038536497 cites W2070594423 @default.
• W2038536497 cites W2070821144 @default.
• W2038536497 cites W2074536099 @default.
• W2038536497 cites W2076713615 @default.
• W2038536497 cites W2080605611 @default.
• W2038536497 cites W2084908485 @default.
• W2038536497 cites W2088423046 @default.
• W2038536497 cites W2089243923 @default.
• W2038536497 cites W2092104135 @default.
• W2038536497 cites W2094514843 @default.
• W2038536497 cites W2097124161 @default.
• W2038536497 cites W2103552916 @default.
• W2038536497 cites W2106443150 @default.
• W2038536497 cites W2108444625 @default.
• W2038536497 cites W2115576017 @default.
• W2038536497 cites W2116594363 @default.
• W2038536497 cites W2117546563 @default.
• W2038536497 cites W2123456626 @default.
• W2038536497 cites W2124322143 @default.
• W2038536497 cites W2124938253 @default.
• W2038536497 cites W2128552081 @default.
• W2038536497 cites W2129954781 @default.
• W2038536497 cites W2143989418 @default.
• W2038536497 cites W2151854650 @default.
• W2038536497 cites W2152645308 @default.
• W2038536497 cites W2154098640 @default.
• W2038536497 cites W2155420844 @default.
• W2038536497 cites W2157811245 @default.
• W2038536497 cites W2158534339 @default.
• W2038536497 cites W2162365619 @default.
• W2038536497 cites W2165912346 @default.
• W2038536497 cites W2166043527 @default.
• W2038536497 cites W2166987747 @default.
• W2038536497 cites W2170030890 @default.
• W2038536497 cites W2774864460 @default.
• W2038536497 doi "https://doi.org/10.1016/j.yexcr.2014.07.018" @default.
• W2038536497 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25062985" @default.
• W2038536497 hasPublicationYear "2014" @default.
• W2038536497 type Work @default.
• W2038536497 sameAs 2038536497 @default.
• W2038536497 citedByCount "28" @default.
• W2038536497 countsByYear W20385364972014 @default.
• W2038536497 countsByYear W20385364972015 @default.
• W2038536497 countsByYear W20385364972016 @default.
• W2038536497 countsByYear W20385364972017 @default.
• W2038536497 countsByYear W20385364972018 @default.
• W2038536497 countsByYear W20385364972019 @default.
• W2038536497 countsByYear W20385364972020 @default.
• W2038536497 countsByYear W20385364972021 @default.
• W2038536497 countsByYear W20385364972022 @default.
• W2038536497 countsByYear W20385364972023 @default.
• W2038536497 crossrefType "journal-article" @default.
• W2038536497 hasAuthorship W2038536497A5023539579 @default.
• W2038536497 hasAuthorship W2038536497A5045629892 @default.
• W2038536497 hasAuthorship W2038536497A5065375123 @default.
• W2038536497 hasConcept C104317684 @default.
• W2038536497 hasConcept C104397665 @default.
• W2038536497 hasConcept C104451858 @default.
• W2038536497 hasConcept C134459356 @default.
• W2038536497 hasConcept C134935766 @default.
• W2038536497 hasConcept C140248907 @default.

• next