Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038551359> ?p ?o ?g. }
- W2038551359 endingPage "2691" @default.
- W2038551359 startingPage "2683" @default.
- W2038551359 abstract "Proton magnetic resonance spectroscopy was used at 3T to measure the uptake and clearance of brain ethanol in rats after bolus intraperitoneal (i.p.) or intragastric (i.g.) alcohol injection, and to estimate the effects of acute alcohol on brain metabolites. The observation duration was 1-1.5 h with temporal resolution of alcohol sampling ranging from 4 s-4 min. The observed time course of alcohol brain concentration followed a consistent pattern characterized by a rapid absorption, an intermediate distribution, and a slower clearance that approached a linear decay. In a sample of eight healthy Wistar rats, the intercept of the linear clearance term, extrapolated back to the time of injection, correlated well with the administered dose per unit of lean body mass. Alcohol concentration estimation based on spectroscopically measured clearance was compared with blood alcohol levels from blood samples at the end of observation, and were in good agreement with the administered dose. Serial proton spectroscopy measurements provide a valid in vivo method for quantifying brain alcohol uptake and elimination kinetics in real time." @default.
- W2038551359 created "2016-06-24" @default.
- W2038551359 creator A5004843559 @default.
- W2038551359 creator A5021214192 @default.
- W2038551359 creator A5065022341 @default.
- W2038551359 creator A5086406917 @default.
- W2038551359 date "2006-01-11" @default.
- W2038551359 modified "2023-10-05" @default.
- W2038551359 title "In Vivo Quantification of Ethanol Kinetics in Rat Brain" @default.
- W2038551359 cites W1965051624 @default.
- W2038551359 cites W1975137667 @default.
- W2038551359 cites W1978675675 @default.
- W2038551359 cites W1980714268 @default.
- W2038551359 cites W1985347928 @default.
- W2038551359 cites W1986621423 @default.
- W2038551359 cites W1986903834 @default.
- W2038551359 cites W1995865564 @default.
- W2038551359 cites W1996448919 @default.
- W2038551359 cites W2000075653 @default.
- W2038551359 cites W2000229085 @default.
- W2038551359 cites W2000796770 @default.
- W2038551359 cites W2005113925 @default.
- W2038551359 cites W2007428718 @default.
- W2038551359 cites W2008943000 @default.
- W2038551359 cites W2014479855 @default.
- W2038551359 cites W2019242961 @default.
- W2038551359 cites W2021716111 @default.
- W2038551359 cites W2022442211 @default.
- W2038551359 cites W2032563329 @default.
- W2038551359 cites W2035188563 @default.
- W2038551359 cites W2037627859 @default.
- W2038551359 cites W2044754726 @default.
- W2038551359 cites W2045165595 @default.
- W2038551359 cites W2045296942 @default.
- W2038551359 cites W2054487801 @default.
- W2038551359 cites W2062239429 @default.
- W2038551359 cites W2062311136 @default.
- W2038551359 cites W2064205606 @default.
- W2038551359 cites W2065906875 @default.
- W2038551359 cites W2068271734 @default.
- W2038551359 cites W2082688434 @default.
- W2038551359 cites W2083489375 @default.
- W2038551359 cites W2083865676 @default.
- W2038551359 cites W2087124149 @default.
- W2038551359 cites W2093552836 @default.
- W2038551359 cites W2096402828 @default.
- W2038551359 cites W2099473986 @default.
- W2038551359 cites W2106946087 @default.
- W2038551359 cites W2114064853 @default.
- W2038551359 cites W2124587548 @default.
- W2038551359 cites W2127319153 @default.
- W2038551359 cites W2127564371 @default.
- W2038551359 cites W2138524791 @default.
- W2038551359 cites W2142509412 @default.
- W2038551359 cites W2145044067 @default.
- W2038551359 cites W2153120191 @default.
- W2038551359 cites W2156390142 @default.
- W2038551359 cites W2160857798 @default.
- W2038551359 doi "https://doi.org/10.1038/sj.npp.1301023" @default.
- W2038551359 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16407891" @default.
- W2038551359 hasPublicationYear "2006" @default.
- W2038551359 type Work @default.
- W2038551359 sameAs 2038551359 @default.
- W2038551359 citedByCount "35" @default.
- W2038551359 countsByYear W20385513592012 @default.
- W2038551359 countsByYear W20385513592013 @default.
- W2038551359 countsByYear W20385513592014 @default.
- W2038551359 countsByYear W20385513592015 @default.
- W2038551359 countsByYear W20385513592016 @default.
- W2038551359 countsByYear W20385513592017 @default.
- W2038551359 countsByYear W20385513592019 @default.
- W2038551359 countsByYear W20385513592020 @default.
- W2038551359 countsByYear W20385513592022 @default.
- W2038551359 crossrefType "journal-article" @default.
- W2038551359 hasAuthorship W2038551359A5004843559 @default.
- W2038551359 hasAuthorship W2038551359A5021214192 @default.
- W2038551359 hasAuthorship W2038551359A5065022341 @default.
- W2038551359 hasAuthorship W2038551359A5086406917 @default.
- W2038551359 hasBestOaLocation W20385513591 @default.
- W2038551359 hasConcept C112705442 @default.
- W2038551359 hasConcept C121332964 @default.
- W2038551359 hasConcept C126322002 @default.
- W2038551359 hasConcept C148898269 @default.
- W2038551359 hasConcept C150903083 @default.
- W2038551359 hasConcept C185592680 @default.
- W2038551359 hasConcept C207001950 @default.
- W2038551359 hasConcept C2780159080 @default.
- W2038551359 hasConcept C2780161600 @default.
- W2038551359 hasConcept C2781066024 @default.
- W2038551359 hasConcept C2988731192 @default.
- W2038551359 hasConcept C43376680 @default.
- W2038551359 hasConcept C55493867 @default.
- W2038551359 hasConcept C62520636 @default.
- W2038551359 hasConcept C71924100 @default.
- W2038551359 hasConcept C86803240 @default.
- W2038551359 hasConcept C98274493 @default.
- W2038551359 hasConceptScore W2038551359C112705442 @default.
- W2038551359 hasConceptScore W2038551359C121332964 @default.