Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038561646> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2038561646 endingPage "195" @default.
- W2038561646 startingPage "191" @default.
- W2038561646 abstract "Fluorescent protein (FP)-based biosensors have revolutionized the ability of researchers to monitor enzyme activities in live cells. While the basic design principles for FP-based biosensors are well established, first-generation biosensor constructs typically suffer from relatively low fluorescence responses that limit their general applicability. The protein engineering efforts required to substantially improve the biosensor responses are often both labour and time intensive. Here we report the application of a high throughput bacterial colony screen for improving the response of kinase biosensors. This effort led to the development of a second-generation cyclin B1-CDK1 biosensor with a 4.5-fold greater response than the first-generation biosensor." @default.
- W2038561646 created "2016-06-24" @default.
- W2038561646 creator A5010299845 @default.
- W2038561646 creator A5032784090 @default.
- W2038561646 creator A5043340480 @default.
- W2038561646 creator A5074910375 @default.
- W2038561646 creator A5086659638 @default.
- W2038561646 date "2014-01-01" @default.
- W2038561646 modified "2023-10-12" @default.
- W2038561646 title "Optimization of a genetically encoded biosensor for cyclin B1-cyclin dependent kinase 1" @default.
- W2038561646 cites W1542263802 @default.
- W2038561646 cites W1726025741 @default.
- W2038561646 cites W1967224802 @default.
- W2038561646 cites W1976136773 @default.
- W2038561646 cites W1980726951 @default.
- W2038561646 cites W1990841830 @default.
- W2038561646 cites W1994667055 @default.
- W2038561646 cites W1995375772 @default.
- W2038561646 cites W2009834607 @default.
- W2038561646 cites W2016258157 @default.
- W2038561646 cites W2038596058 @default.
- W2038561646 cites W2040231021 @default.
- W2038561646 cites W2057553906 @default.
- W2038561646 cites W2059536603 @default.
- W2038561646 cites W2061137513 @default.
- W2038561646 cites W2061842603 @default.
- W2038561646 cites W2081852526 @default.
- W2038561646 cites W2082128798 @default.
- W2038561646 cites W2082770517 @default.
- W2038561646 cites W2083288707 @default.
- W2038561646 cites W2086310064 @default.
- W2038561646 cites W2113974479 @default.
- W2038561646 cites W2118726157 @default.
- W2038561646 cites W2160084442 @default.
- W2038561646 cites W2165402321 @default.
- W2038561646 cites W2171889714 @default.
- W2038561646 doi "https://doi.org/10.1039/c3mb70402e" @default.
- W2038561646 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24281384" @default.
- W2038561646 hasPublicationYear "2014" @default.
- W2038561646 type Work @default.
- W2038561646 sameAs 2038561646 @default.
- W2038561646 citedByCount "21" @default.
- W2038561646 countsByYear W20385616462014 @default.
- W2038561646 countsByYear W20385616462015 @default.
- W2038561646 countsByYear W20385616462016 @default.
- W2038561646 countsByYear W20385616462017 @default.
- W2038561646 countsByYear W20385616462018 @default.
- W2038561646 countsByYear W20385616462019 @default.
- W2038561646 countsByYear W20385616462021 @default.
- W2038561646 countsByYear W20385616462022 @default.
- W2038561646 countsByYear W20385616462023 @default.
- W2038561646 crossrefType "journal-article" @default.
- W2038561646 hasAuthorship W2038561646A5010299845 @default.
- W2038561646 hasAuthorship W2038561646A5032784090 @default.
- W2038561646 hasAuthorship W2038561646A5043340480 @default.
- W2038561646 hasAuthorship W2038561646A5074910375 @default.
- W2038561646 hasAuthorship W2038561646A5086659638 @default.
- W2038561646 hasBestOaLocation W20385616461 @default.
- W2038561646 hasConcept C120504264 @default.
- W2038561646 hasConcept C1491633281 @default.
- W2038561646 hasConcept C160756335 @default.
- W2038561646 hasConcept C184235292 @default.
- W2038561646 hasConcept C29537977 @default.
- W2038561646 hasConcept C55493867 @default.
- W2038561646 hasConcept C86803240 @default.
- W2038561646 hasConcept C95444343 @default.
- W2038561646 hasConceptScore W2038561646C120504264 @default.
- W2038561646 hasConceptScore W2038561646C1491633281 @default.
- W2038561646 hasConceptScore W2038561646C160756335 @default.
- W2038561646 hasConceptScore W2038561646C184235292 @default.
- W2038561646 hasConceptScore W2038561646C29537977 @default.
- W2038561646 hasConceptScore W2038561646C55493867 @default.
- W2038561646 hasConceptScore W2038561646C86803240 @default.
- W2038561646 hasConceptScore W2038561646C95444343 @default.
- W2038561646 hasIssue "2" @default.
- W2038561646 hasLocation W20385616461 @default.
- W2038561646 hasLocation W20385616462 @default.
- W2038561646 hasOpenAccess W2038561646 @default.
- W2038561646 hasPrimaryLocation W20385616461 @default.
- W2038561646 hasRelatedWork W14542710 @default.
- W2038561646 hasRelatedWork W1511369931 @default.
- W2038561646 hasRelatedWork W1517644997 @default.
- W2038561646 hasRelatedWork W2030313547 @default.
- W2038561646 hasRelatedWork W2038407368 @default.
- W2038561646 hasRelatedWork W2069939932 @default.
- W2038561646 hasRelatedWork W2070278756 @default.
- W2038561646 hasRelatedWork W2408072120 @default.
- W2038561646 hasRelatedWork W4255724027 @default.
- W2038561646 hasRelatedWork W4295346438 @default.
- W2038561646 hasVolume "10" @default.
- W2038561646 isParatext "false" @default.
- W2038561646 isRetracted "false" @default.
- W2038561646 magId "2038561646" @default.
- W2038561646 workType "article" @default.