FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038563353> ?p ?o ?g. }

• W2038563353 endingPage "579" @default.
• W2038563353 startingPage "567" @default.
• W2038563353 abstract "A series of 23 new 1-methyl-2-alkenyl-4(1H)quinolones have been synthesized and evaluated in vitro for their antimycobacterial activities against fast growing species of mycobacteria, such as Mycobacterium fortuitum, M. smegmatis and M. phlei. The compounds displayed good to excellent inhibition of the growth of the mycobacterial test strains with improved antimycobacterial activity compared to the hit compound, evocarpine. The most active compounds, which possessed chain length of 11–13 carbons at position-2 displayed potent inhibitory effects with an MIC value of 1.0 mg/L. In a human diploid embryonic lung cell line, MRC-5 cytotoxicity assay, the alkaloids showed weak to moderate cytotoxic activity. Biological evaluation of these evocarpine analogues on the less pathogenic fast growing strains of mycobacteria showed an interesting antimycobacterial profile and provided significant insight into the structure–activity relationships." @default.
• W2038563353 created "2016-06-24" @default.
• W2038563353 creator A5012672741 @default.
• W2038563353 creator A5016219933 @default.
• W2038563353 creator A5027041544 @default.
• W2038563353 creator A5028569456 @default.
• W2038563353 creator A5057895676 @default.
• W2038563353 creator A5072105385 @default.
• W2038563353 creator A5089800381 @default.
• W2038563353 date "2011-01-01" @default.
• W2038563353 modified "2023-09-23" @default.
• W2038563353 title "Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl-4(1H)-quinolones" @default.
• W2038563353 cites W1827264465 @default.
• W2038563353 cites W1974554226 @default.
• W2038563353 cites W1982805048 @default.
• W2038563353 cites W1986061180 @default.
• W2038563353 cites W1996569320 @default.
• W2038563353 cites W2002649699 @default.
• W2038563353 cites W2006902431 @default.
• W2038563353 cites W2009488821 @default.
• W2038563353 cites W2013299486 @default.
• W2038563353 cites W2019123088 @default.
• W2038563353 cites W2060540282 @default.
• W2038563353 cites W2122798739 @default.
• W2038563353 cites W2949345764 @default.
• W2038563353 doi "https://doi.org/10.1016/j.bmc.2010.10.060" @default.
• W2038563353 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3268452" @default.
• W2038563353 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21106378" @default.
• W2038563353 hasPublicationYear "2011" @default.
• W2038563353 type Work @default.
• W2038563353 sameAs 2038563353 @default.
• W2038563353 citedByCount "60" @default.
• W2038563353 countsByYear W20385633532012 @default.
• W2038563353 countsByYear W20385633532013 @default.
• W2038563353 countsByYear W20385633532014 @default.
• W2038563353 countsByYear W20385633532015 @default.
• W2038563353 countsByYear W20385633532016 @default.
• W2038563353 countsByYear W20385633532017 @default.
• W2038563353 countsByYear W20385633532018 @default.
• W2038563353 countsByYear W20385633532019 @default.
• W2038563353 countsByYear W20385633532020 @default.
• W2038563353 countsByYear W20385633532021 @default.
• W2038563353 countsByYear W20385633532022 @default.
• W2038563353 countsByYear W20385633532023 @default.
• W2038563353 crossrefType "journal-article" @default.
• W2038563353 hasAuthorship W2038563353A5012672741 @default.
• W2038563353 hasAuthorship W2038563353A5016219933 @default.
• W2038563353 hasAuthorship W2038563353A5027041544 @default.
• W2038563353 hasAuthorship W2038563353A5028569456 @default.
• W2038563353 hasAuthorship W2038563353A5057895676 @default.
• W2038563353 hasAuthorship W2038563353A5072105385 @default.
• W2038563353 hasAuthorship W2038563353A5089800381 @default.
• W2038563353 hasBestOaLocation W20385633531 @default.
• W2038563353 hasConcept C109316439 @default.
• W2038563353 hasConcept C116073593 @default.
• W2038563353 hasConcept C142724271 @default.
• W2038563353 hasConcept C176947019 @default.
• W2038563353 hasConcept C185592680 @default.
• W2038563353 hasConcept C202751555 @default.
• W2038563353 hasConcept C2777204207 @default.
• W2038563353 hasConcept C2777931070 @default.
• W2038563353 hasConcept C2777975735 @default.
• W2038563353 hasConcept C2779317461 @default.
• W2038563353 hasConcept C2779685592 @default.
• W2038563353 hasConcept C2780104969 @default.
• W2038563353 hasConcept C2780374374 @default.
• W2038563353 hasConcept C2781069245 @default.
• W2038563353 hasConcept C3019249092 @default.
• W2038563353 hasConcept C501593827 @default.
• W2038563353 hasConcept C523546767 @default.
• W2038563353 hasConcept C54355233 @default.
• W2038563353 hasConcept C55493867 @default.
• W2038563353 hasConcept C71240020 @default.
• W2038563353 hasConcept C71924100 @default.
• W2038563353 hasConcept C86803240 @default.
• W2038563353 hasConcept C89423630 @default.
• W2038563353 hasConceptScore W2038563353C109316439 @default.
• W2038563353 hasConceptScore W2038563353C116073593 @default.
• W2038563353 hasConceptScore W2038563353C142724271 @default.
• W2038563353 hasConceptScore W2038563353C176947019 @default.
• W2038563353 hasConceptScore W2038563353C185592680 @default.
• W2038563353 hasConceptScore W2038563353C202751555 @default.
• W2038563353 hasConceptScore W2038563353C2777204207 @default.
• W2038563353 hasConceptScore W2038563353C2777931070 @default.
• W2038563353 hasConceptScore W2038563353C2777975735 @default.
• W2038563353 hasConceptScore W2038563353C2779317461 @default.
• W2038563353 hasConceptScore W2038563353C2779685592 @default.
• W2038563353 hasConceptScore W2038563353C2780104969 @default.
• W2038563353 hasConceptScore W2038563353C2780374374 @default.
• W2038563353 hasConceptScore W2038563353C2781069245 @default.
• W2038563353 hasConceptScore W2038563353C3019249092 @default.
• W2038563353 hasConceptScore W2038563353C501593827 @default.
• W2038563353 hasConceptScore W2038563353C523546767 @default.
• W2038563353 hasConceptScore W2038563353C54355233 @default.
• W2038563353 hasConceptScore W2038563353C55493867 @default.
• W2038563353 hasConceptScore W2038563353C71240020 @default.
• W2038563353 hasConceptScore W2038563353C71924100 @default.
• W2038563353 hasConceptScore W2038563353C86803240 @default.

• next