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• W2038577032 endingPage "20" @default.
• W2038577032 startingPage "7" @default.
• W2038577032 abstract "A method is presented for the two-dimensional thin-layer Chromatographie screening of purines, pyrimidines and their nucleosides in the urine. Prior to chromatography, isolation of these substances from the urine is performed by anion-exchange column chromatography. Purines and pyrimidines are quantitively eluted with formic acid 0.01 M and 4 M respectively. The results of recovery and stability experiments are given. Normal excretory patterns are presented. Also results in patients with various diseases are shown: ornithine transcarbamylase deficiency, adenosine deaminase deficiency, purine nucleoside phosphorylase deficiency, adenine phosphoribosyltransferase deficiency, xanthine oxidase deficiency and hypoxanthine-guanine] phosphoribosyltransferase deficiency. Finally the pattern of a patient on treatment with allopurinol is given." @default.
• W2038577032 created "2016-06-24" @default.
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• W2038577032 date "1978-05-01" @default.
• W2038577032 modified "2023-10-07" @default.
• W2038577032 title "Two-dimensional thin-layer chromatography for the screening of disorders of purine and pyrimidine metabolism" @default.
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• W2038577032 doi "https://doi.org/10.1016/0009-8981(78)90452-7" @default.
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