FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038588512> ?p ?o ?g. }

• W2038588512 endingPage "1559" @default.
• W2038588512 startingPage "1554" @default.
• W2038588512 abstract "Lung transplantation impairs surfactant activity, which may contribute to primary graft dysfunction (PGD). Prompted by studies in animals and a few reports in humans, this study sought to determine if the administration of surfactant during transplantation serves as an effective preventive measure.An open, randomized, controlled prospective design was used. Forty-two patients scheduled for single (n=38) or double (n=4) lung transplantation at a major tertiary medical center were randomly assigned to receive, or not, intraoperative surfactant treatment. In the treated group, bovine surfactant was administered at a dose of 20 mg phospholipids/kg through bronchoscope after the establishment of bronchial anastomosis. The groups were compared for oxygenation (PaO2/FiO2), chest X-ray findings, PGD grade, and outcome.Compared with the untreated group, the patients who received surfactant were characterized by better postoperative oxygenation mean PaO2/FiO2 (418.8+/-123.8 vs. 277.9+/-165 mm Hg, P=0.004), better chest radiograph score, a lower PGD grade (0.66 vs. 1.86, P=0.005), fewer cases of severe PGD (1 patient vs. 12, P<0.05), earlier extubation (by 2.2 hr; 95% CI 1.1-4.3 hr, P=0.027), shorter intensive care unit stay (by 2.3 days; 95% CI 1.47-3.74 days, P=0.001), and better vital capacity at 1 month (61% vs. 50%, P=0.022). One treated and 2 untreated patients died during the first postoperative month.Surfactant instillation during lung transplantation improves oxygenation, prevents PGD, shortens intubation time, and enhances early posttransplantation recovery. Further, larger studies are needed to assess whether surfactant should be used routinely in lung transplantation." @default.
• W2038588512 created "2016-06-24" @default.
• W2038588512 creator A5029439315 @default.
• W2038588512 creator A5033863532 @default.
• W2038588512 creator A5043933608 @default.
• W2038588512 creator A5046803053 @default.
• W2038588512 creator A5051629469 @default.
• W2038588512 creator A5086193526 @default.
• W2038588512 creator A5089438028 @default.
• W2038588512 date "2008-12-15" @default.
• W2038588512 modified "2023-09-26" @default.
• W2038588512 title "The Use of Surfactant in Lung Transplantation" @default.
• W2038588512 cites W1830425508 @default.
• W2038588512 cites W1969229405 @default.
• W2038588512 cites W1970200006 @default.
• W2038588512 cites W1980536166 @default.
• W2038588512 cites W1983688860 @default.
• W2038588512 cites W2000267911 @default.
• W2038588512 cites W2000549992 @default.
• W2038588512 cites W2023700096 @default.
• W2038588512 cites W2054143887 @default.
• W2038588512 cites W2057256800 @default.
• W2038588512 cites W2063701339 @default.
• W2038588512 cites W2066992732 @default.
• W2038588512 cites W2078687096 @default.
• W2038588512 cites W2080903862 @default.
• W2038588512 cites W2082920253 @default.
• W2038588512 cites W2083793991 @default.
• W2038588512 cites W2085461684 @default.
• W2038588512 cites W2096783798 @default.
• W2038588512 cites W2100148817 @default.
• W2038588512 cites W2104037780 @default.
• W2038588512 cites W2110023782 @default.
• W2038588512 cites W2116469597 @default.
• W2038588512 cites W2125078269 @default.
• W2038588512 cites W2130870749 @default.
• W2038588512 cites W2137731450 @default.
• W2038588512 cites W2139305884 @default.
• W2038588512 cites W2142358723 @default.
• W2038588512 cites W2152076473 @default.
• W2038588512 cites W2165305878 @default.
• W2038588512 cites W2335075431 @default.
• W2038588512 cites W2414350926 @default.
• W2038588512 cites W3022308733 @default.
• W2038588512 cites W4231860663 @default.
• W2038588512 doi "https://doi.org/10.1097/tp.0b013e31818a8418" @default.
• W2038588512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19077889" @default.
• W2038588512 hasPublicationYear "2008" @default.
• W2038588512 type Work @default.
• W2038588512 sameAs 2038588512 @default.
• W2038588512 citedByCount "26" @default.
• W2038588512 countsByYear W20385885122012 @default.
• W2038588512 countsByYear W20385885122013 @default.
• W2038588512 countsByYear W20385885122014 @default.
• W2038588512 countsByYear W20385885122015 @default.
• W2038588512 countsByYear W20385885122017 @default.
• W2038588512 countsByYear W20385885122018 @default.
• W2038588512 countsByYear W20385885122019 @default.
• W2038588512 countsByYear W20385885122020 @default.
• W2038588512 countsByYear W20385885122021 @default.
• W2038588512 countsByYear W20385885122022 @default.
• W2038588512 countsByYear W20385885122023 @default.
• W2038588512 crossrefType "journal-article" @default.
• W2038588512 hasAuthorship W2038588512A5029439315 @default.
• W2038588512 hasAuthorship W2038588512A5033863532 @default.
• W2038588512 hasAuthorship W2038588512A5043933608 @default.
• W2038588512 hasAuthorship W2038588512A5046803053 @default.
• W2038588512 hasAuthorship W2038588512A5051629469 @default.
• W2038588512 hasAuthorship W2038588512A5086193526 @default.
• W2038588512 hasAuthorship W2038588512A5089438028 @default.
• W2038588512 hasBestOaLocation W20385885121 @default.
• W2038588512 hasConcept C121332964 @default.
• W2038588512 hasConcept C126322002 @default.
• W2038588512 hasConcept C141071460 @default.
• W2038588512 hasConcept C2776376669 @default.
• W2038588512 hasConcept C2777714996 @default.
• W2038588512 hasConcept C2778716859 @default.
• W2038588512 hasConcept C2781137159 @default.
• W2038588512 hasConcept C2781448352 @default.
• W2038588512 hasConcept C2911091166 @default.
• W2038588512 hasConcept C42219234 @default.
• W2038588512 hasConcept C58226133 @default.
• W2038588512 hasConcept C70289976 @default.
• W2038588512 hasConcept C71924100 @default.
• W2038588512 hasConcept C90924648 @default.
• W2038588512 hasConcept C97355855 @default.
• W2038588512 hasConceptScore W2038588512C121332964 @default.
• W2038588512 hasConceptScore W2038588512C126322002 @default.
• W2038588512 hasConceptScore W2038588512C141071460 @default.
• W2038588512 hasConceptScore W2038588512C2776376669 @default.
• W2038588512 hasConceptScore W2038588512C2777714996 @default.
• W2038588512 hasConceptScore W2038588512C2778716859 @default.
• W2038588512 hasConceptScore W2038588512C2781137159 @default.
• W2038588512 hasConceptScore W2038588512C2781448352 @default.
• W2038588512 hasConceptScore W2038588512C2911091166 @default.
• W2038588512 hasConceptScore W2038588512C42219234 @default.
• W2038588512 hasConceptScore W2038588512C58226133 @default.
• W2038588512 hasConceptScore W2038588512C70289976 @default.

• next