FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038605906> ?p ?o ?g. }

• W2038605906 endingPage "1399" @default.
• W2038605906 startingPage "1392" @default.
• W2038605906 abstract "IgE antibodies specific for the major birch-pollen allergen, Bet v 1, cross-react with homologous allergens in particular foods, e.g. apples, carrots and hazelnuts. In a high number of tree pollen-allergic individuals, this cross-reactivity causes clinical symptoms, commonly known as the 'birch-fruit-syndrome'.To characterize the T cell response to the Bet v 1-related major allergen in hazelnuts, Cor a 1.04, and its cellular cross-reactivity with Bet v 1 and the homologous hazel pollen allergen, Cor a 1.Using recombinant Cor a 1.04, T cell lines (TCL) and T cell clones (TCC) were established from peripheral blood mononuclear cells of tree pollen-allergic patients with associated food allergy. T cell epitopes were determined using overlapping synthetic peptides in Cor a 1.04-reactive TCL and TCC. In parallel, reactivity to Bet v 1 and Cor a 1 was tested.In total, 20 distinct T cell epitopes on the hazelnut allergen were identified. Several Cor a 1.04-specific TCL and TCC reacted with pollen allergens albeit less pronounced than with the hazelnut allergen. Several Cor a 1.04-specific TCC did not react with pollen allergens. Interestingly, these clones were found to react with the Bet v 1-related major allergen in carrots, Dau c 1. The cellular cross-reactivity between both food allergens could be associated with the most frequently recognized T cell epitope of Cor a 1.04, Cor a 1.04(142-153).The major hazelnut allergen cross-reacts with the major allergens of birch and hazel pollen but apparently contains a relevant T cell epitope not shared with pollen allergens. Our finding may have important implications for the specific immunotherapy of tree pollen-allergic patients suffering from concomitant hazelnut allergy." @default.
• W2038605906 created "2016-06-24" @default.
• W2038605906 creator A5006758370 @default.
• W2038605906 creator A5019539923 @default.
• W2038605906 creator A5026230972 @default.
• W2038605906 creator A5051906875 @default.
• W2038605906 creator A5070189560 @default.
• W2038605906 creator A5081407448 @default.
• W2038605906 date "2005-10-01" @default.
• W2038605906 modified "2023-09-27" @default.
• W2038605906 title "Characterization of the T cell response to the major hazelnut allergen, Cor a 1.04: evidence for a relevant T cell epitope not cross-reactive with homologous pollen allergens" @default.
• W2038605906 cites W135930570 @default.
• W2038605906 cites W1480346494 @default.
• W2038605906 cites W1537072931 @default.
• W2038605906 cites W1554768670 @default.
• W2038605906 cites W1605338221 @default.
• W2038605906 cites W1967906336 @default.
• W2038605906 cites W1968323951 @default.
• W2038605906 cites W1969754518 @default.
• W2038605906 cites W1970672159 @default.
• W2038605906 cites W1971596331 @default.
• W2038605906 cites W1972513797 @default.
• W2038605906 cites W1976176385 @default.
• W2038605906 cites W1990253099 @default.
• W2038605906 cites W1998418938 @default.
• W2038605906 cites W2000279446 @default.
• W2038605906 cites W2000831686 @default.
• W2038605906 cites W2003902333 @default.
• W2038605906 cites W2007719882 @default.
• W2038605906 cites W2008921531 @default.
• W2038605906 cites W2018282794 @default.
• W2038605906 cites W2018514098 @default.
• W2038605906 cites W2024954306 @default.
• W2038605906 cites W2034740531 @default.
• W2038605906 cites W2039737010 @default.
• W2038605906 cites W2045927667 @default.
• W2038605906 cites W2046759597 @default.
• W2038605906 cites W2047172463 @default.
• W2038605906 cites W2051276205 @default.
• W2038605906 cites W2051378111 @default.
• W2038605906 cites W2079547247 @default.
• W2038605906 cites W2079557289 @default.
• W2038605906 cites W2086413751 @default.
• W2038605906 cites W2089657316 @default.
• W2038605906 cites W2090667820 @default.
• W2038605906 cites W2104042418 @default.
• W2038605906 cites W2105855231 @default.
• W2038605906 cites W2109593104 @default.
• W2038605906 cites W2119853022 @default.
• W2038605906 cites W2127092918 @default.
• W2038605906 cites W2130886030 @default.
• W2038605906 cites W2140806800 @default.
• W2038605906 cites W2157119191 @default.
• W2038605906 cites W2170036507 @default.
• W2038605906 cites W2171058206 @default.
• W2038605906 doi "https://doi.org/10.1111/j.1365-2222.2005.02332.x" @default.
• W2038605906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16238801" @default.
• W2038605906 hasPublicationYear "2005" @default.
• W2038605906 type Work @default.
• W2038605906 sameAs 2038605906 @default.
• W2038605906 citedByCount "42" @default.
• W2038605906 countsByYear W20386059062012 @default.
• W2038605906 countsByYear W20386059062013 @default.
• W2038605906 countsByYear W20386059062015 @default.
• W2038605906 countsByYear W20386059062016 @default.
• W2038605906 countsByYear W20386059062017 @default.
• W2038605906 countsByYear W20386059062018 @default.
• W2038605906 countsByYear W20386059062020 @default.
• W2038605906 countsByYear W20386059062021 @default.
• W2038605906 countsByYear W20386059062022 @default.
• W2038605906 countsByYear W20386059062023 @default.
• W2038605906 crossrefType "journal-article" @default.
• W2038605906 hasAuthorship W2038605906A5006758370 @default.
• W2038605906 hasAuthorship W2038605906A5019539923 @default.
• W2038605906 hasAuthorship W2038605906A5026230972 @default.
• W2038605906 hasAuthorship W2038605906A5051906875 @default.
• W2038605906 hasAuthorship W2038605906A5070189560 @default.
• W2038605906 hasAuthorship W2038605906A5081407448 @default.
• W2038605906 hasConcept C104317684 @default.
• W2038605906 hasConcept C141105273 @default.
• W2038605906 hasConcept C159654299 @default.
• W2038605906 hasConcept C185592680 @default.
• W2038605906 hasConcept C195616568 @default.
• W2038605906 hasConcept C203014093 @default.
• W2038605906 hasConcept C207480886 @default.
• W2038605906 hasConcept C2776090121 @default.
• W2038605906 hasConcept C2779142602 @default.
• W2038605906 hasConcept C2780510475 @default.
• W2038605906 hasConcept C2780618852 @default.
• W2038605906 hasConcept C3020064264 @default.
• W2038605906 hasConcept C40767141 @default.
• W2038605906 hasConcept C55493867 @default.
• W2038605906 hasConcept C59822182 @default.
• W2038605906 hasConcept C86803240 @default.
• W2038605906 hasConcept C8891405 @default.
• W2038605906 hasConceptScore W2038605906C104317684 @default.
• W2038605906 hasConceptScore W2038605906C141105273 @default.
• W2038605906 hasConceptScore W2038605906C159654299 @default.

• next