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• W2038606471 abstract "A series of cationic porphyrins carrying 1–3 meso-N-pyridinium groups has been synthesised, and their binding to G-quadruplex DNA has been explored by surface plasmon resonance (SPR) and circular dichroism spectroscopy. Two trans substituents appear to be sufficient for tight binding; preferential binding to the anti-parallel intramolecular human telomeric DNA was observed for the A2trans and A3 porphyrins. The A2trans is able to induce the formation of an anti-parallel G-quadruplex in a K+ free solution, mimicking the effect of a molecular chaperone." @default.
• W2038606471 created "2016-06-24" @default.
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• W2038606471 date "2006-01-01" @default.
• W2038606471 modified "2023-09-26" @default.
• W2038606471 title "Synthesis and G-quadruplex binding studies of new 4-N-methylpyridinium porphyrins" @default.
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• W2038606471 doi "https://doi.org/10.1039/b608494j" @default.
• W2038606471 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2195891" @default.
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