Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038608420> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2038608420 endingPage "340" @default.
- W2038608420 startingPage "337" @default.
- W2038608420 abstract "OBJECTIVE: The neurotrophins, antioxidant enzymes and oxidative markers have reciprocal interactions. This report verified in chronically stable medicated schizophrenic patients whether there are correlations between the serum levels of superoxide dismutase, a key enzyme in the antioxidant defense, thiobarbituric acid reactive substances, a direct index of lipid peroxidation, and brain-derived neurotrophic factor, the most widely distributed neurotrophin. METHOD: Sixty DSM-IV schizophrenic patients were included (43 males, 17 females). Mean age was 34.7 ± 10.8 years, mean age at first episode was 19.8 ± 7.9 years, and mean illness duration was 14.9 ± 8.5 years. Each subject had a blood sample collected for the determination of serum levels of brain-derived neurotrophic factor, thiobarbituric acid reactive substances and superoxide dismutase. RESULTS: Brain-derived neurotrophic factor levels showed a positive correlation with thiobarbituric acid reactive substances levels (r = 0.333, p = 0.009). Brain-derived neurotrophic factor levels were not correlated with superoxide dismutase levels (r = - 0.181, p = 0.166), and superoxide dismutase levels were not correlated with thiobarbituric acid reactive substances levels (r = 0.141, p = 0.284). CONCLUSIONS: The positive correlation between brain-derived neurotrophic factor and thiobarbituric acid reactive substances suggests the need of further investigation on intracellular interactions of neurotrophins, antioxidant enzymes and oxidative markers. In addition, this opens a venue for investigation on treatments for the prevention of neurotoxicity along the course of schizophrenia." @default.
- W2038608420 created "2016-06-24" @default.
- W2038608420 creator A5001223332 @default.
- W2038608420 creator A5004564167 @default.
- W2038608420 creator A5020318192 @default.
- W2038608420 creator A5066511141 @default.
- W2038608420 creator A5078882374 @default.
- W2038608420 date "2008-12-01" @default.
- W2038608420 modified "2023-10-14" @default.
- W2038608420 title "Serum levels of brain-derived neurotrophic factor and thiobarbituric acid reactive substances in chronically medicated schizophrenic patients: a positive correlation" @default.
- W2038608420 cites W1825808183 @default.
- W2038608420 cites W1975098857 @default.
- W2038608420 cites W1976969521 @default.
- W2038608420 cites W1997585036 @default.
- W2038608420 cites W2011152776 @default.
- W2038608420 cites W2024851966 @default.
- W2038608420 cites W2039403132 @default.
- W2038608420 cites W2039636801 @default.
- W2038608420 cites W2054985002 @default.
- W2038608420 cites W2070947242 @default.
- W2038608420 cites W2093015590 @default.
- W2038608420 cites W2129695795 @default.
- W2038608420 cites W2131671310 @default.
- W2038608420 doi "https://doi.org/10.1590/s1516-44462008000400006" @default.
- W2038608420 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19142408" @default.
- W2038608420 hasPublicationYear "2008" @default.
- W2038608420 type Work @default.
- W2038608420 sameAs 2038608420 @default.
- W2038608420 citedByCount "29" @default.
- W2038608420 countsByYear W20386084202012 @default.
- W2038608420 countsByYear W20386084202013 @default.
- W2038608420 countsByYear W20386084202014 @default.
- W2038608420 countsByYear W20386084202015 @default.
- W2038608420 countsByYear W20386084202016 @default.
- W2038608420 countsByYear W20386084202020 @default.
- W2038608420 countsByYear W20386084202021 @default.
- W2038608420 countsByYear W20386084202022 @default.
- W2038608420 crossrefType "journal-article" @default.
- W2038608420 hasAuthorship W2038608420A5001223332 @default.
- W2038608420 hasAuthorship W2038608420A5004564167 @default.
- W2038608420 hasAuthorship W2038608420A5020318192 @default.
- W2038608420 hasAuthorship W2038608420A5066511141 @default.
- W2038608420 hasAuthorship W2038608420A5078882374 @default.
- W2038608420 hasBestOaLocation W20386084201 @default.
- W2038608420 hasConcept C126322002 @default.
- W2038608420 hasConcept C134018914 @default.
- W2038608420 hasConcept C160539049 @default.
- W2038608420 hasConcept C170493617 @default.
- W2038608420 hasConcept C185592680 @default.
- W2038608420 hasConcept C2775838275 @default.
- W2038608420 hasConcept C2776151105 @default.
- W2038608420 hasConcept C2777352226 @default.
- W2038608420 hasConcept C2777504301 @default.
- W2038608420 hasConcept C2778004101 @default.
- W2038608420 hasConcept C2778790584 @default.
- W2038608420 hasConcept C2780829032 @default.
- W2038608420 hasConcept C55493867 @default.
- W2038608420 hasConcept C71924100 @default.
- W2038608420 hasConceptScore W2038608420C126322002 @default.
- W2038608420 hasConceptScore W2038608420C134018914 @default.
- W2038608420 hasConceptScore W2038608420C160539049 @default.
- W2038608420 hasConceptScore W2038608420C170493617 @default.
- W2038608420 hasConceptScore W2038608420C185592680 @default.
- W2038608420 hasConceptScore W2038608420C2775838275 @default.
- W2038608420 hasConceptScore W2038608420C2776151105 @default.
- W2038608420 hasConceptScore W2038608420C2777352226 @default.
- W2038608420 hasConceptScore W2038608420C2777504301 @default.
- W2038608420 hasConceptScore W2038608420C2778004101 @default.
- W2038608420 hasConceptScore W2038608420C2778790584 @default.
- W2038608420 hasConceptScore W2038608420C2780829032 @default.
- W2038608420 hasConceptScore W2038608420C55493867 @default.
- W2038608420 hasConceptScore W2038608420C71924100 @default.
- W2038608420 hasIssue "4" @default.
- W2038608420 hasLocation W20386084201 @default.
- W2038608420 hasLocation W20386084202 @default.
- W2038608420 hasLocation W20386084203 @default.
- W2038608420 hasLocation W20386084204 @default.
- W2038608420 hasOpenAccess W2038608420 @default.
- W2038608420 hasPrimaryLocation W20386084201 @default.
- W2038608420 hasRelatedWork W1566607623 @default.
- W2038608420 hasRelatedWork W1987505311 @default.
- W2038608420 hasRelatedWork W2021584934 @default.
- W2038608420 hasRelatedWork W2038608420 @default.
- W2038608420 hasRelatedWork W2113027094 @default.
- W2038608420 hasRelatedWork W2186050858 @default.
- W2038608420 hasRelatedWork W1932750572 @default.
- W2038608420 hasRelatedWork W2188195501 @default.
- W2038608420 hasRelatedWork W2608151465 @default.
- W2038608420 hasRelatedWork W2994394112 @default.
- W2038608420 hasVolume "30" @default.
- W2038608420 isParatext "false" @default.
- W2038608420 isRetracted "false" @default.
- W2038608420 magId "2038608420" @default.
- W2038608420 workType "article" @default.