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• W2038636697 abstract "It is becoming increasingly apparent that natural killer (NK) cells play a crucial role in innate defense mechanisms against Mycobacterium tuberculosis infection. Furthermore, NK cell functions are dependent on adequate levels of glutathione. In this study, we examined whether the NK cell-mediated growth control of intracellular M. tuberculosis is dependent on adequate levels of glutathione. We investigated the effects of glutathione both alone and in combination with interleukin-2 (IL-2) or IL-12 or both in modulating NK cell functions, such as cytolytic activity, activating receptor expression, induction of apoptosis, and cytokine synthesis. Our results strongly indicate that glutathione in combination with IL-2+IL-12 augments NK cell functions, leading to control M. tuberculosis infection." @default.
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• W2038636697 date "2008-03-01" @default.
• W2038636697 modified "2023-10-14" @default.
• W2038636697 title "Natural Killer Cells, Glutathione, Cytokines, and Innate Immunity Against<i>Mycobacterium tuberculosis</i>" @default.
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• W2038636697 doi "https://doi.org/10.1089/jir.2007.0095" @default.
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