Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038664256> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2038664256 endingPage "376" @default.
- W2038664256 startingPage "369" @default.
- W2038664256 abstract "In adult male rats, injection of TRH into a lateral ventricle of the brain 5 min prior to pentobarbital (PB) administration caused a significant dose-related inhibition of prolactin (PRL) release, in doses ranging from 500 to 5 ng. Among 8 TRH analogues devoid of thyrotropin-releasing activity, 6 were found to significantly suppress PB-induced PRL secretion at an intraventricular dose level of 10 μg, and the 3 most effective in this respect were also able to counteract growth hormone (GH) release elicited by PB. The derivative [1,3′-DCM2]TRH was still potent enough to block PB-induced PRL secretion at an intraventricular dosage of 50 ng. The peptide ACTH 4–10 was ineffective, whereas another ACTH derivative H-Met(O2)-Glu-His-Phe-D-Lys-Phe-OH (Org 2766) reduced PRL release. TRH did not affect the increase of plasma PRL induced by acute stress. α-Methyl-p-tyrosine (α-MT) failed to influence the inhibiting effect of TRH on GH secretion but significantly reduced that on PRL release. p-Chlorophenylalanine (PCPA) completely blocked the antagonistic effect of TRH on all PB-induced hormonal changes, suggesting that serotoninergic mechanisms may be involved in the extra-pituitary effects of TRH." @default.
- W2038664256 created "2016-06-24" @default.
- W2038664256 creator A5010241733 @default.
- W2038664256 creator A5030957244 @default.
- W2038664256 creator A5050023199 @default.
- W2038664256 creator A5079472507 @default.
- W2038664256 date "1977-10-01" @default.
- W2038664256 modified "2023-10-03" @default.
- W2038664256 title "Antagonism of pentobarbital-induced hormonal changes by TRH in rats" @default.
- W2038664256 cites W1974741752 @default.
- W2038664256 cites W1994068597 @default.
- W2038664256 cites W1995124766 @default.
- W2038664256 cites W1997653766 @default.
- W2038664256 cites W1999393604 @default.
- W2038664256 cites W2008390160 @default.
- W2038664256 cites W2018830255 @default.
- W2038664256 cites W2020367384 @default.
- W2038664256 cites W2021189922 @default.
- W2038664256 cites W2027411819 @default.
- W2038664256 cites W2043193575 @default.
- W2038664256 cites W2045993936 @default.
- W2038664256 cites W2049690950 @default.
- W2038664256 cites W2064955150 @default.
- W2038664256 cites W2066966451 @default.
- W2038664256 cites W2077440438 @default.
- W2038664256 cites W2090363655 @default.
- W2038664256 cites W2091738619 @default.
- W2038664256 cites W2095388238 @default.
- W2038664256 cites W2096472505 @default.
- W2038664256 cites W2101924795 @default.
- W2038664256 cites W2149330955 @default.
- W2038664256 cites W2160801616 @default.
- W2038664256 cites W2164406177 @default.
- W2038664256 cites W2165406383 @default.
- W2038664256 cites W2286576779 @default.
- W2038664256 doi "https://doi.org/10.1016/0014-2999(77)90276-x" @default.
- W2038664256 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/200440" @default.
- W2038664256 hasPublicationYear "1977" @default.
- W2038664256 type Work @default.
- W2038664256 sameAs 2038664256 @default.
- W2038664256 citedByCount "8" @default.
- W2038664256 crossrefType "journal-article" @default.
- W2038664256 hasAuthorship W2038664256A5010241733 @default.
- W2038664256 hasAuthorship W2038664256A5030957244 @default.
- W2038664256 hasAuthorship W2038664256A5050023199 @default.
- W2038664256 hasAuthorship W2038664256A5079472507 @default.
- W2038664256 hasConcept C126322002 @default.
- W2038664256 hasConcept C134018914 @default.
- W2038664256 hasConcept C170493617 @default.
- W2038664256 hasConcept C185592680 @default.
- W2038664256 hasConcept C2775864247 @default.
- W2038664256 hasConcept C2776216936 @default.
- W2038664256 hasConcept C2776755955 @default.
- W2038664256 hasConcept C2777003273 @default.
- W2038664256 hasConcept C2779064019 @default.
- W2038664256 hasConcept C37000724 @default.
- W2038664256 hasConcept C49039625 @default.
- W2038664256 hasConcept C71315377 @default.
- W2038664256 hasConcept C71924100 @default.
- W2038664256 hasConcept C86803240 @default.
- W2038664256 hasConceptScore W2038664256C126322002 @default.
- W2038664256 hasConceptScore W2038664256C134018914 @default.
- W2038664256 hasConceptScore W2038664256C170493617 @default.
- W2038664256 hasConceptScore W2038664256C185592680 @default.
- W2038664256 hasConceptScore W2038664256C2775864247 @default.
- W2038664256 hasConceptScore W2038664256C2776216936 @default.
- W2038664256 hasConceptScore W2038664256C2776755955 @default.
- W2038664256 hasConceptScore W2038664256C2777003273 @default.
- W2038664256 hasConceptScore W2038664256C2779064019 @default.
- W2038664256 hasConceptScore W2038664256C37000724 @default.
- W2038664256 hasConceptScore W2038664256C49039625 @default.
- W2038664256 hasConceptScore W2038664256C71315377 @default.
- W2038664256 hasConceptScore W2038664256C71924100 @default.
- W2038664256 hasConceptScore W2038664256C86803240 @default.
- W2038664256 hasIssue "4" @default.
- W2038664256 hasLocation W20386642561 @default.
- W2038664256 hasLocation W20386642562 @default.
- W2038664256 hasOpenAccess W2038664256 @default.
- W2038664256 hasPrimaryLocation W20386642561 @default.
- W2038664256 hasRelatedWork W2031905651 @default.
- W2038664256 hasRelatedWork W2033209790 @default.
- W2038664256 hasRelatedWork W2033668374 @default.
- W2038664256 hasRelatedWork W2062579683 @default.
- W2038664256 hasRelatedWork W2080367469 @default.
- W2038664256 hasRelatedWork W2161296685 @default.
- W2038664256 hasRelatedWork W2163744984 @default.
- W2038664256 hasRelatedWork W2417077803 @default.
- W2038664256 hasRelatedWork W2429164444 @default.
- W2038664256 hasRelatedWork W3166306376 @default.
- W2038664256 hasVolume "45" @default.
- W2038664256 isParatext "false" @default.
- W2038664256 isRetracted "false" @default.
- W2038664256 magId "2038664256" @default.
- W2038664256 workType "article" @default.