Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038672807> ?p ?o ?g. }
- W2038672807 endingPage "447" @default.
- W2038672807 startingPage "438" @default.
- W2038672807 abstract "The manifestation of tumor lysis syndrome (TLS) occurs when the destruction of tumor cells releases breakdown products that overwhelm the excretory mechanisms of the body. A cardinal sign is hyperuricemia, leading to uric acid nephropathy. Other signs are hyperkalemia, hyperphosphatemia and secondary hypocalcemia. Conventional management of TLS consists of aggressive intravenous hydration, diuretic therapy, urinary alkalization, and inhibition of urate production by high-dose allopurinol. Urate oxidase has been used in the management of patients at risk for TLS and recently the recombinant urate oxidase rasburicase was developed. Several data indicate that rasburicase is effective and well tolerated in the prevention and treatment of chemotherapy-induced hyperuricemia. Treatment options of hyperkalemia include sodium polystyrene sulfonate, hypertonic glucose and insulin, loop diuretics, and bicarbonate. Treatment of hyperphosphatemia reduces dietary phosphate intake and includes phosphate binders such as aluminum hydroxide and aluminum carbonate. When recurrent hypocalcemia is present, a continuous intravenous infusion of calcium gluconate can be initiated. Hemodialysis should be considered for every patient with excessively elevated uric acid, phosphate and/or potassium and in those patients with acute renal failure to control urinary volume and manage uremia." @default.
- W2038672807 created "2016-06-24" @default.
- W2038672807 creator A5023822012 @default.
- W2038672807 creator A5053067949 @default.
- W2038672807 creator A5054291981 @default.
- W2038672807 date "2006-08-01" @default.
- W2038672807 modified "2023-10-16" @default.
- W2038672807 title "The management of tumor lysis syndrome" @default.
- W2038672807 cites W1483901766 @default.
- W2038672807 cites W1605032945 @default.
- W2038672807 cites W1754054048 @default.
- W2038672807 cites W1965099310 @default.
- W2038672807 cites W1965528254 @default.
- W2038672807 cites W1966551456 @default.
- W2038672807 cites W1968008584 @default.
- W2038672807 cites W1969854740 @default.
- W2038672807 cites W1971079475 @default.
- W2038672807 cites W1984261114 @default.
- W2038672807 cites W1985604311 @default.
- W2038672807 cites W1986453845 @default.
- W2038672807 cites W2000678469 @default.
- W2038672807 cites W2002189955 @default.
- W2038672807 cites W2004286802 @default.
- W2038672807 cites W2005472750 @default.
- W2038672807 cites W2006219673 @default.
- W2038672807 cites W2012796352 @default.
- W2038672807 cites W2015683713 @default.
- W2038672807 cites W2019458594 @default.
- W2038672807 cites W2020473773 @default.
- W2038672807 cites W2023127465 @default.
- W2038672807 cites W2029370731 @default.
- W2038672807 cites W2031528608 @default.
- W2038672807 cites W2033941212 @default.
- W2038672807 cites W2038277986 @default.
- W2038672807 cites W2039891689 @default.
- W2038672807 cites W2044527405 @default.
- W2038672807 cites W2048993523 @default.
- W2038672807 cites W2050000571 @default.
- W2038672807 cites W2052142040 @default.
- W2038672807 cites W2053406788 @default.
- W2038672807 cites W2054152447 @default.
- W2038672807 cites W2054598042 @default.
- W2038672807 cites W2055686397 @default.
- W2038672807 cites W2071337636 @default.
- W2038672807 cites W2071958183 @default.
- W2038672807 cites W2072723458 @default.
- W2038672807 cites W2074673300 @default.
- W2038672807 cites W2075536073 @default.
- W2038672807 cites W2076654890 @default.
- W2038672807 cites W2094679036 @default.
- W2038672807 cites W2094941986 @default.
- W2038672807 cites W2095026923 @default.
- W2038672807 cites W2095331188 @default.
- W2038672807 cites W2098453700 @default.
- W2038672807 cites W2123530845 @default.
- W2038672807 cites W2129876366 @default.
- W2038672807 cites W2134138207 @default.
- W2038672807 cites W2135955308 @default.
- W2038672807 cites W2154947537 @default.
- W2038672807 cites W2155080284 @default.
- W2038672807 cites W2155880198 @default.
- W2038672807 cites W2161444726 @default.
- W2038672807 cites W2165447689 @default.
- W2038672807 cites W2167654982 @default.
- W2038672807 cites W2167774253 @default.
- W2038672807 cites W2260803760 @default.
- W2038672807 cites W2332209737 @default.
- W2038672807 cites W2335021499 @default.
- W2038672807 cites W2336623503 @default.
- W2038672807 cites W2341370931 @default.
- W2038672807 cites W2399885082 @default.
- W2038672807 cites W2463183114 @default.
- W2038672807 cites W4238768696 @default.
- W2038672807 cites W4240456779 @default.
- W2038672807 doi "https://doi.org/10.1038/ncponc0581" @default.
- W2038672807 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16894389" @default.
- W2038672807 hasPublicationYear "2006" @default.
- W2038672807 type Work @default.
- W2038672807 sameAs 2038672807 @default.
- W2038672807 citedByCount "106" @default.
- W2038672807 countsByYear W20386728072012 @default.
- W2038672807 countsByYear W20386728072013 @default.
- W2038672807 countsByYear W20386728072014 @default.
- W2038672807 countsByYear W20386728072015 @default.
- W2038672807 countsByYear W20386728072016 @default.
- W2038672807 countsByYear W20386728072017 @default.
- W2038672807 countsByYear W20386728072018 @default.
- W2038672807 countsByYear W20386728072019 @default.
- W2038672807 countsByYear W20386728072020 @default.
- W2038672807 countsByYear W20386728072021 @default.
- W2038672807 countsByYear W20386728072022 @default.
- W2038672807 countsByYear W20386728072023 @default.
- W2038672807 crossrefType "journal-article" @default.
- W2038672807 hasAuthorship W2038672807A5023822012 @default.
- W2038672807 hasAuthorship W2038672807A5053067949 @default.
- W2038672807 hasAuthorship W2038672807A5054291981 @default.
- W2038672807 hasBestOaLocation W20386728071 @default.
- W2038672807 hasConcept C126322002 @default.