FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038702953> ?p ?o ?g. }

• W2038702953 endingPage "e52331" @default.
• W2038702953 startingPage "e52331" @default.
• W2038702953 abstract "Brain-derived neurotropic factor (BDNF) was originally described in the nervous system but has been shown to be expressed in ovary tissues recently, acting as a paracrine/autocrine regulator required for developments of follicles and oocytes. Although it is generally accepted that chronic stress impairs female reproduction and decreases the expression of BDNF in limbic structures of central nervous system, which contributes to mood disorder. However, it is not known whether chronic stress affects oocytes developments, nor whether it affects expression of BDNF in ovary.Mice were randomly assigned into control group, stressed group, BDNF-treated group and BDNF-treated stressed group. The chronic unpredictable mild stress model was used to produce psychosocial stress in mice, and the model was verified by open field test and hypothalamic-pituitary-adrenal (HPA) axis activity. The methods of immunohistochemistry and western blotting were used to detect BDNF protein level and distribution. The number of retrieved oocytes, oocyte maturation, embryo cleavage and the rates of blastocyst formation after parthenogenetic activation were evaluated.Chronic unpredictable stress decreased the BDNF expression in antral follicles, but didn't affect the BDNF expression in primordial, primary and secondary follicles. Chronic unpredictable stress also decreased the number of retrieved oocytes and the rate of blastocyst formation, which was rescued by exogenous BDNF treatment.BDNF in mouse ovaries may be related to the decreased number of retrieved oocytes and impaired oocytes developmental potential induced by chronic unpredictable stress." @default.
• W2038702953 created "2016-06-24" @default.
• W2038702953 creator A5004733447 @default.
• W2038702953 creator A5010130989 @default.
• W2038702953 creator A5011692095 @default.
• W2038702953 creator A5013093316 @default.
• W2038702953 creator A5031528890 @default.
• W2038702953 creator A5035056540 @default.
• W2038702953 creator A5046597133 @default.
• W2038702953 creator A5064722818 @default.
• W2038702953 creator A5072836685 @default.
• W2038702953 creator A5082411086 @default.
• W2038702953 date "2012-12-20" @default.
• W2038702953 modified "2023-10-01" @default.
• W2038702953 title "Chronic Unpredictable Stress Decreases Expression of Brain-Derived Neurotrophic Factor (BDNF) in Mouse Ovaries: Relationship to Oocytes Developmental Potential" @default.
• W2038702953 cites W1775749144 @default.
• W2038702953 cites W1967075670 @default.
• W2038702953 cites W1969062959 @default.
• W2038702953 cites W1977430165 @default.
• W2038702953 cites W1992469404 @default.
• W2038702953 cites W1994017777 @default.
• W2038702953 cites W2008113854 @default.
• W2038702953 cites W2010621696 @default.
• W2038702953 cites W2014817906 @default.
• W2038702953 cites W2020990588 @default.
• W2038702953 cites W2025887442 @default.
• W2038702953 cites W2034141271 @default.
• W2038702953 cites W2044191023 @default.
• W2038702953 cites W2044464834 @default.
• W2038702953 cites W2058786533 @default.
• W2038702953 cites W2067847949 @default.
• W2038702953 cites W2078037269 @default.
• W2038702953 cites W2078116925 @default.
• W2038702953 cites W2080785485 @default.
• W2038702953 cites W2089198034 @default.
• W2038702953 cites W2108087762 @default.
• W2038702953 cites W2110074893 @default.
• W2038702953 cites W2114599730 @default.
• W2038702953 cites W2121178994 @default.
• W2038702953 cites W2126605121 @default.
• W2038702953 cites W2128560658 @default.
• W2038702953 cites W2129072528 @default.
• W2038702953 cites W2134222140 @default.
• W2038702953 cites W2152501253 @default.
• W2038702953 cites W2157449467 @default.
• W2038702953 cites W2182638746 @default.
• W2038702953 doi "https://doi.org/10.1371/journal.pone.0052331" @default.
• W2038702953 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3527516" @default.
• W2038702953 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23284991" @default.
• W2038702953 hasPublicationYear "2012" @default.
• W2038702953 type Work @default.
• W2038702953 sameAs 2038702953 @default.
• W2038702953 citedByCount "36" @default.
• W2038702953 countsByYear W20387029532014 @default.
• W2038702953 countsByYear W20387029532015 @default.
• W2038702953 countsByYear W20387029532016 @default.
• W2038702953 countsByYear W20387029532017 @default.
• W2038702953 countsByYear W20387029532019 @default.
• W2038702953 countsByYear W20387029532020 @default.
• W2038702953 countsByYear W20387029532021 @default.
• W2038702953 countsByYear W20387029532022 @default.
• W2038702953 countsByYear W20387029532023 @default.
• W2038702953 crossrefType "journal-article" @default.
• W2038702953 hasAuthorship W2038702953A5004733447 @default.
• W2038702953 hasAuthorship W2038702953A5010130989 @default.
• W2038702953 hasAuthorship W2038702953A5011692095 @default.
• W2038702953 hasAuthorship W2038702953A5013093316 @default.
• W2038702953 hasAuthorship W2038702953A5031528890 @default.
• W2038702953 hasAuthorship W2038702953A5035056540 @default.
• W2038702953 hasAuthorship W2038702953A5046597133 @default.
• W2038702953 hasAuthorship W2038702953A5064722818 @default.
• W2038702953 hasAuthorship W2038702953A5072836685 @default.
• W2038702953 hasAuthorship W2038702953A5082411086 @default.
• W2038702953 hasBestOaLocation W20387029531 @default.
• W2038702953 hasConcept C126322002 @default.
• W2038702953 hasConcept C128240485 @default.
• W2038702953 hasConcept C134018914 @default.
• W2038702953 hasConcept C160539049 @default.
• W2038702953 hasConcept C170493617 @default.
• W2038702953 hasConcept C196843134 @default.
• W2038702953 hasConcept C2776690073 @default.
• W2038702953 hasConcept C2778654844 @default.
• W2038702953 hasConcept C2778790584 @default.
• W2038702953 hasConcept C71924100 @default.
• W2038702953 hasConcept C86803240 @default.
• W2038702953 hasConcept C95444343 @default.
• W2038702953 hasConceptScore W2038702953C126322002 @default.
• W2038702953 hasConceptScore W2038702953C128240485 @default.
• W2038702953 hasConceptScore W2038702953C134018914 @default.
• W2038702953 hasConceptScore W2038702953C160539049 @default.
• W2038702953 hasConceptScore W2038702953C170493617 @default.
• W2038702953 hasConceptScore W2038702953C196843134 @default.
• W2038702953 hasConceptScore W2038702953C2776690073 @default.
• W2038702953 hasConceptScore W2038702953C2778654844 @default.
• W2038702953 hasConceptScore W2038702953C2778790584 @default.
• W2038702953 hasConceptScore W2038702953C71924100 @default.
• W2038702953 hasConceptScore W2038702953C86803240 @default.
• W2038702953 hasConceptScore W2038702953C95444343 @default.

• next