Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038726489> ?p ?o ?g. }
- W2038726489 endingPage "2699" @default.
- W2038726489 startingPage "2692" @default.
- W2038726489 abstract "Synthetic studies directed toward a total synthesis of clavulactone are reported. In light of the analysis made in our previous work, cyclopentane 4a (a key intermediate in the present work) was synthesized through a radical-mediated ring closure of a rationally designed substrate 25. Using HWE reactions, the lower and upper side-chains of 4a were converted into an allyl chloride and an allyl cyanohydrin, respectively. Subsequent treatment of the allyl chloride/cyanohydrin in a highly diluted THF solution with sodium bis(trimethylsiliyl)amide led to intramolecular alkylation and thus completed a major endeavor in synthesizing the dolabellane framework, construction of the eleven-membered ring. SmI(2)-mediated lactonization as a model reaction for the formation of the alpha,beta-unsaturated delta-lactone segment of clavulactone is also described." @default.
- W2038726489 created "2016-06-24" @default.
- W2038726489 creator A5030057165 @default.
- W2038726489 creator A5036743939 @default.
- W2038726489 creator A5066599544 @default.
- W2038726489 creator A5078471037 @default.
- W2038726489 date "2001-03-20" @default.
- W2038726489 modified "2023-10-09" @default.
- W2038726489 title "Studies toward the Total Synthesis of Clavulactone" @default.
- W2038726489 cites W1968360823 @default.
- W2038726489 cites W1982316932 @default.
- W2038726489 cites W1985997458 @default.
- W2038726489 cites W1988565581 @default.
- W2038726489 cites W1996604847 @default.
- W2038726489 cites W1999139342 @default.
- W2038726489 cites W2024437471 @default.
- W2038726489 cites W2030930300 @default.
- W2038726489 cites W2033393782 @default.
- W2038726489 cites W2049897244 @default.
- W2038726489 cites W2062346383 @default.
- W2038726489 cites W2063222716 @default.
- W2038726489 cites W2089155442 @default.
- W2038726489 cites W2159293324 @default.
- W2038726489 cites W2883223019 @default.
- W2038726489 cites W2951054370 @default.
- W2038726489 cites W2951997472 @default.
- W2038726489 cites W2952598217 @default.
- W2038726489 cites W2952899373 @default.
- W2038726489 cites W2953288619 @default.
- W2038726489 cites W3005275105 @default.
- W2038726489 cites W4240392186 @default.
- W2038726489 doi "https://doi.org/10.1021/jo005683f" @default.
- W2038726489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11304189" @default.
- W2038726489 hasPublicationYear "2001" @default.
- W2038726489 type Work @default.
- W2038726489 sameAs 2038726489 @default.
- W2038726489 citedByCount "21" @default.
- W2038726489 countsByYear W20387264892012 @default.
- W2038726489 countsByYear W20387264892013 @default.
- W2038726489 countsByYear W20387264892014 @default.
- W2038726489 countsByYear W20387264892015 @default.
- W2038726489 countsByYear W20387264892017 @default.
- W2038726489 countsByYear W20387264892019 @default.
- W2038726489 crossrefType "journal-article" @default.
- W2038726489 hasAuthorship W2038726489A5030057165 @default.
- W2038726489 hasAuthorship W2038726489A5036743939 @default.
- W2038726489 hasAuthorship W2038726489A5066599544 @default.
- W2038726489 hasAuthorship W2038726489A5078471037 @default.
- W2038726489 hasConcept C111368507 @default.
- W2038726489 hasConcept C127313418 @default.
- W2038726489 hasConcept C155647269 @default.
- W2038726489 hasConcept C161790260 @default.
- W2038726489 hasConcept C164361826 @default.
- W2038726489 hasConcept C178790620 @default.
- W2038726489 hasConcept C185592680 @default.
- W2038726489 hasConcept C2776612806 @default.
- W2038726489 hasConcept C2777289219 @default.
- W2038726489 hasConcept C2778439535 @default.
- W2038726489 hasConcept C2778556512 @default.
- W2038726489 hasConcept C2778910044 @default.
- W2038726489 hasConcept C2780352964 @default.
- W2038726489 hasConcept C2780378348 @default.
- W2038726489 hasConcept C35753019 @default.
- W2038726489 hasConcept C75079739 @default.
- W2038726489 hasConceptScore W2038726489C111368507 @default.
- W2038726489 hasConceptScore W2038726489C127313418 @default.
- W2038726489 hasConceptScore W2038726489C155647269 @default.
- W2038726489 hasConceptScore W2038726489C161790260 @default.
- W2038726489 hasConceptScore W2038726489C164361826 @default.
- W2038726489 hasConceptScore W2038726489C178790620 @default.
- W2038726489 hasConceptScore W2038726489C185592680 @default.
- W2038726489 hasConceptScore W2038726489C2776612806 @default.
- W2038726489 hasConceptScore W2038726489C2777289219 @default.
- W2038726489 hasConceptScore W2038726489C2778439535 @default.
- W2038726489 hasConceptScore W2038726489C2778556512 @default.
- W2038726489 hasConceptScore W2038726489C2778910044 @default.
- W2038726489 hasConceptScore W2038726489C2780352964 @default.
- W2038726489 hasConceptScore W2038726489C2780378348 @default.
- W2038726489 hasConceptScore W2038726489C35753019 @default.
- W2038726489 hasConceptScore W2038726489C75079739 @default.
- W2038726489 hasIssue "8" @default.
- W2038726489 hasLocation W20387264891 @default.
- W2038726489 hasLocation W20387264892 @default.
- W2038726489 hasOpenAccess W2038726489 @default.
- W2038726489 hasPrimaryLocation W20387264891 @default.
- W2038726489 hasRelatedWork W1976215611 @default.
- W2038726489 hasRelatedWork W2009696536 @default.
- W2038726489 hasRelatedWork W2021649219 @default.
- W2038726489 hasRelatedWork W2024347016 @default.
- W2038726489 hasRelatedWork W2038726489 @default.
- W2038726489 hasRelatedWork W214349708 @default.
- W2038726489 hasRelatedWork W2362162061 @default.
- W2038726489 hasRelatedWork W2370963446 @default.
- W2038726489 hasRelatedWork W2890877707 @default.
- W2038726489 hasRelatedWork W4317823539 @default.
- W2038726489 hasVolume "66" @default.
- W2038726489 isParatext "false" @default.
- W2038726489 isRetracted "false" @default.