FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038730113> ?p ?o ?g. }

• W2038730113 endingPage "985" @default.
• W2038730113 startingPage "979" @default.
• W2038730113 abstract "Both acute and chronic graft-versus-host disease (GVHD) are major causes of morbidity and mortality in patients undergoing allogeneic hematopoietic stem cell transplantation (AHSCT). The optimal pharmacological regimen for GVHD prophylaxis is unclear, but combinations of a calcineurin inhibitor (cyclosporin or tacrolimus [Tac]) and an antimetabolite (methotrexate or mycophenolate mofetil [MMF]) are typically used. We retrospectively evaluated the clinical outcomes of 414 consecutive patients who underwent AHSCT from sibling (SD) or unrelated donors (UD) with Tac/MMF combination, between January 2005 and August 2010. The median follow-up was 60 months. Less than one third of the patients received a reduced-intensity chemoregimen. The incidence of grades III and IV acute GVHD was 22.3% and 36.5% in SD and UD groups, respectively (P = .0007). The incidence of chronic GVHD was 47.1% and 52.7% in the SD and UD groups, respectively. Nonrelapse mortality (NRM) at 60 months was 33.3% and 46.5% in the SD and UD groups, respectively (P = .0016). The incidence of relapse was 22.4% for UD and 28.8% for SD. Five-year overall survival was 43% and 34% in the SD and UD groups, respectively (P = .0183). GVHD was the leading cause of death for the entire cohort. Multivariable analysis showed that 8/8 HLA match, patient's age < 60, and low-risk disease were associated with better survival. The use of Tac/MMF for GVHD prophylaxis was associated with a relatively high incidence of severe acute GVHD and NRM in AHSCT from sibling and unrelated donors." @default.
• W2038730113 created "2016-06-24" @default.
• W2038730113 creator A5005086749 @default.
• W2038730113 creator A5011386306 @default.
• W2038730113 creator A5027863398 @default.
• W2038730113 creator A5042677328 @default.
• W2038730113 creator A5045603763 @default.
• W2038730113 creator A5046786751 @default.
• W2038730113 creator A5051092535 @default.
• W2038730113 creator A5055027283 @default.
• W2038730113 creator A5055577800 @default.
• W2038730113 creator A5086538924 @default.
• W2038730113 creator A5091089490 @default.
• W2038730113 date "2014-07-01" @default.
• W2038730113 modified "2023-10-18" @default.
• W2038730113 title "High Incidence of Severe Acute Graft-Versus-Host Disease with Tacrolimus and Mycophenolate Mofetil in a Large Cohort of Related and Unrelated Allogeneic Transplantation Patients" @default.
• W2038730113 cites W1611277150 @default.
• W2038730113 cites W1887371789 @default.
• W2038730113 cites W1968998293 @default.
• W2038730113 cites W1972263355 @default.
• W2038730113 cites W1974030738 @default.
• W2038730113 cites W1974172212 @default.
• W2038730113 cites W1977086270 @default.
• W2038730113 cites W1978288530 @default.
• W2038730113 cites W1988769943 @default.
• W2038730113 cites W1994520227 @default.
• W2038730113 cites W2001895625 @default.
• W2038730113 cites W2022940423 @default.
• W2038730113 cites W2023971040 @default.
• W2038730113 cites W2024037242 @default.
• W2038730113 cites W2029921434 @default.
• W2038730113 cites W2034208644 @default.
• W2038730113 cites W2036170089 @default.
• W2038730113 cites W2039808932 @default.
• W2038730113 cites W2044061245 @default.
• W2038730113 cites W2044560944 @default.
• W2038730113 cites W2045254759 @default.
• W2038730113 cites W2045456189 @default.
• W2038730113 cites W2054075974 @default.
• W2038730113 cites W2055468114 @default.
• W2038730113 cites W2061069485 @default.
• W2038730113 cites W2061117723 @default.
• W2038730113 cites W2061458797 @default.
• W2038730113 cites W2080200044 @default.
• W2038730113 cites W2083436670 @default.
• W2038730113 cites W2088211433 @default.
• W2038730113 cites W2090823852 @default.
• W2038730113 cites W2101802089 @default.
• W2038730113 cites W2122645489 @default.
• W2038730113 cites W2127036836 @default.
• W2038730113 cites W2129789149 @default.
• W2038730113 cites W2131706663 @default.
• W2038730113 cites W2133072316 @default.
• W2038730113 cites W2137022752 @default.
• W2038730113 cites W2140143467 @default.
• W2038730113 cites W2144789671 @default.
• W2038730113 cites W2153643980 @default.
• W2038730113 cites W2164885965 @default.
• W2038730113 cites W2313376640 @default.
• W2038730113 cites W2323935864 @default.
• W2038730113 cites W2618073389 @default.
• W2038730113 cites W4256106911 @default.
• W2038730113 doi "https://doi.org/10.1016/j.bbmt.2014.03.016" @default.
• W2038730113 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4110977" @default.
• W2038730113 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24709007" @default.
• W2038730113 hasPublicationYear "2014" @default.
• W2038730113 type Work @default.
• W2038730113 sameAs 2038730113 @default.
• W2038730113 citedByCount "36" @default.
• W2038730113 countsByYear W20387301132014 @default.
• W2038730113 countsByYear W20387301132015 @default.
• W2038730113 countsByYear W20387301132016 @default.
• W2038730113 countsByYear W20387301132017 @default.
• W2038730113 countsByYear W20387301132018 @default.
• W2038730113 countsByYear W20387301132019 @default.
• W2038730113 countsByYear W20387301132020 @default.
• W2038730113 countsByYear W20387301132021 @default.
• W2038730113 countsByYear W20387301132022 @default.
• W2038730113 countsByYear W20387301132023 @default.
• W2038730113 crossrefType "journal-article" @default.
• W2038730113 hasAuthorship W2038730113A5005086749 @default.
• W2038730113 hasAuthorship W2038730113A5011386306 @default.
• W2038730113 hasAuthorship W2038730113A5027863398 @default.
• W2038730113 hasAuthorship W2038730113A5042677328 @default.
• W2038730113 hasAuthorship W2038730113A5045603763 @default.
• W2038730113 hasAuthorship W2038730113A5046786751 @default.
• W2038730113 hasAuthorship W2038730113A5051092535 @default.
• W2038730113 hasAuthorship W2038730113A5055027283 @default.
• W2038730113 hasAuthorship W2038730113A5055577800 @default.
• W2038730113 hasAuthorship W2038730113A5086538924 @default.
• W2038730113 hasAuthorship W2038730113A5091089490 @default.
• W2038730113 hasBestOaLocation W20387301131 @default.
• W2038730113 hasConcept C120665830 @default.
• W2038730113 hasConcept C121332964 @default.
• W2038730113 hasConcept C126322002 @default.
• W2038730113 hasConcept C128057223 @default.
• W2038730113 hasConcept C141071460 @default.
• W2038730113 hasConcept C167135981 @default.

• next