Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038742017> ?p ?o ?g. }
- W2038742017 endingPage "21" @default.
- W2038742017 startingPage "14" @default.
- W2038742017 abstract "Chitin oligosaccharides (NA–COS) of two different molecular weight ranges (below 1 and 1–3 kDa) were examined for their capabilities against lipopolysaccharide-induced inflammatory responses in BV-2 murine microglia. It was found that NA–COS reduced the level of nitric oxide (NO) and prostaglandin E2 (PGE2) production by suppressing the expression of NO synthase (iNOS) and cyclooxygenase (COX)-2 without significant cytotoxicity. Furthermore, the inhibitory effects of NA–COS on generation of interleukin (IL)-1β, IL-6, and tumor necrosis factor (TNF)-α were determined. Notably, NA–COS exerted anti-inflammatory activities via blocking degradation of inhibitor of kappaB-alpha (IκB-α), translocation of nuclear factor (NF)-κB, and phosphorylation of mitogen-activated protein kinases (MAPKs) in a dose-dependent manner. These findings provide mechanistic insights into the anti-inflammatory and neuroprotective actions of NA–COS in BV-2 microglia." @default.
- W2038742017 created "2016-06-24" @default.
- W2038742017 creator A5029208692 @default.
- W2038742017 creator A5034973872 @default.
- W2038742017 creator A5037284987 @default.
- W2038742017 creator A5055141718 @default.
- W2038742017 creator A5055296388 @default.
- W2038742017 creator A5057057975 @default.
- W2038742017 date "2012-05-01" @default.
- W2038742017 modified "2023-10-14" @default.
- W2038742017 title "Protective effect of chitin oligosaccharides against lipopolysaccharide-induced inflammatory response in BV-2 microglia" @default.
- W2038742017 cites W1482019136 @default.
- W2038742017 cites W1975331070 @default.
- W2038742017 cites W1980452558 @default.
- W2038742017 cites W1980969896 @default.
- W2038742017 cites W1981711366 @default.
- W2038742017 cites W1995193883 @default.
- W2038742017 cites W1998849703 @default.
- W2038742017 cites W2000964873 @default.
- W2038742017 cites W2012347071 @default.
- W2038742017 cites W2017081112 @default.
- W2038742017 cites W2018831724 @default.
- W2038742017 cites W2033082385 @default.
- W2038742017 cites W2037747961 @default.
- W2038742017 cites W2043290296 @default.
- W2038742017 cites W2047075715 @default.
- W2038742017 cites W2055163087 @default.
- W2038742017 cites W2063774153 @default.
- W2038742017 cites W2064437259 @default.
- W2038742017 cites W2068504832 @default.
- W2038742017 cites W2074939616 @default.
- W2038742017 cites W2077346158 @default.
- W2038742017 cites W2089039364 @default.
- W2038742017 cites W2105924651 @default.
- W2038742017 cites W2110777046 @default.
- W2038742017 cites W2111425451 @default.
- W2038742017 cites W2112736681 @default.
- W2038742017 cites W2116605894 @default.
- W2038742017 cites W2127209631 @default.
- W2038742017 cites W2134673353 @default.
- W2038742017 cites W2142023329 @default.
- W2038742017 cites W2145016962 @default.
- W2038742017 cites W2146798875 @default.
- W2038742017 cites W2147457499 @default.
- W2038742017 cites W2157137975 @default.
- W2038742017 cites W2160399092 @default.
- W2038742017 cites W2163751922 @default.
- W2038742017 cites W2165092386 @default.
- W2038742017 cites W2331176038 @default.
- W2038742017 doi "https://doi.org/10.1016/j.cellimm.2012.06.005" @default.
- W2038742017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22763270" @default.
- W2038742017 hasPublicationYear "2012" @default.
- W2038742017 type Work @default.
- W2038742017 sameAs 2038742017 @default.
- W2038742017 citedByCount "30" @default.
- W2038742017 countsByYear W20387420172014 @default.
- W2038742017 countsByYear W20387420172015 @default.
- W2038742017 countsByYear W20387420172016 @default.
- W2038742017 countsByYear W20387420172017 @default.
- W2038742017 countsByYear W20387420172018 @default.
- W2038742017 countsByYear W20387420172019 @default.
- W2038742017 countsByYear W20387420172020 @default.
- W2038742017 countsByYear W20387420172021 @default.
- W2038742017 countsByYear W20387420172022 @default.
- W2038742017 countsByYear W20387420172023 @default.
- W2038742017 crossrefType "journal-article" @default.
- W2038742017 hasAuthorship W2038742017A5029208692 @default.
- W2038742017 hasAuthorship W2038742017A5034973872 @default.
- W2038742017 hasAuthorship W2038742017A5037284987 @default.
- W2038742017 hasAuthorship W2038742017A5055141718 @default.
- W2038742017 hasAuthorship W2038742017A5055296388 @default.
- W2038742017 hasAuthorship W2038742017A5057057975 @default.
- W2038742017 hasConcept C109316439 @default.
- W2038742017 hasConcept C11960822 @default.
- W2038742017 hasConcept C134018914 @default.
- W2038742017 hasConcept C153911025 @default.
- W2038742017 hasConcept C17991360 @default.
- W2038742017 hasConcept C184235292 @default.
- W2038742017 hasConcept C185592680 @default.
- W2038742017 hasConcept C202751555 @default.
- W2038742017 hasConcept C203014093 @default.
- W2038742017 hasConcept C25498285 @default.
- W2038742017 hasConcept C2776914184 @default.
- W2038742017 hasConcept C2777622882 @default.
- W2038742017 hasConcept C2777956040 @default.
- W2038742017 hasConcept C2778754761 @default.
- W2038742017 hasConcept C2779830541 @default.
- W2038742017 hasConcept C519581460 @default.
- W2038742017 hasConcept C55493867 @default.
- W2038742017 hasConcept C86803240 @default.
- W2038742017 hasConcept C87753298 @default.
- W2038742017 hasConcept C98274493 @default.
- W2038742017 hasConceptScore W2038742017C109316439 @default.
- W2038742017 hasConceptScore W2038742017C11960822 @default.
- W2038742017 hasConceptScore W2038742017C134018914 @default.
- W2038742017 hasConceptScore W2038742017C153911025 @default.
- W2038742017 hasConceptScore W2038742017C17991360 @default.
- W2038742017 hasConceptScore W2038742017C184235292 @default.