Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038748154> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2038748154 abstract "With the advent of highly active antiretroviral therapy (HAART), HIV infection has become a chronic condition in children with improved survival and quality of life. Reports on long term effectiveness of non-nucleoside reverse transcriptase inhibitor based HAART in HIV-infected children in developing countries are limited. A chart review was conducted and children who received at least six months of HAART between 2004–2011 at All India Institute of Medical Sciences (AIIMS), Delhi were included. The clinical, immunological and virological responses to HAART were documented. Factors predicting non-adherence and non-response to treatment were described. One seventy five children (boys: 74.9%) were included in the study, with a median follow up of 43 (IQR:17, 68) months. The median age at diagnosis was 119 (IQR: 75, 156) months. The median CD4 count at start of HAART was 340 cells/μL (IQR: 185,704), which increased to 924 cells/μL (IQR:591,1278) at 48 months after HAART and plateaued at 749 (IQR: 542,1056) cells/ μL after 90 months of therapy. The weight for age (WAZ) and height for age (HAZ) z score both showed improvement with time after HAART initiation [baseline: WAZ −2.8 (IQR:-4,-1.6), HAZ −2.1 (IQR:-3.4,-0.69); at 42 months of therapy: WAZ −1.2 (IQR:-2.1, 0.01), HAZ −0.75(IQR:-1.6,-0.37)]. Adverse events were reported in 21 (12%) children. Non-adherence to therapy, treatment failure and death were noted in 35 (20%), 9 (5.1%) and 6 (3.4%) children respectively. Our experience shows that HAART in HIV-infected children is effective, safe and is associated with good immunological and virological response as well as improvement in growth parameters." @default.
- W2038748154 created "2016-06-24" @default.
- W2038748154 creator A5009761215 @default.
- W2038748154 creator A5034642104 @default.
- W2038748154 creator A5039572099 @default.
- W2038748154 creator A5052407990 @default.
- W2038748154 creator A5060490422 @default.
- W2038748154 creator A5061842330 @default.
- W2038748154 date "2014-12-01" @default.
- W2038748154 modified "2023-10-15" @default.
- W2038748154 title "Outcome of highly active antiretroviral therapy in HIV- infected Indian children" @default.
- W2038748154 cites W1484620035 @default.
- W2038748154 cites W1791774898 @default.
- W2038748154 cites W1967299169 @default.
- W2038748154 cites W1978255992 @default.
- W2038748154 cites W1989387083 @default.
- W2038748154 cites W2031551729 @default.
- W2038748154 cites W2050293156 @default.
- W2038748154 cites W2052226147 @default.
- W2038748154 cites W2061469087 @default.
- W2038748154 cites W2075790800 @default.
- W2038748154 cites W2096561020 @default.
- W2038748154 cites W2097345834 @default.
- W2038748154 cites W2127184526 @default.
- W2038748154 cites W2132247532 @default.
- W2038748154 cites W2132355267 @default.
- W2038748154 cites W2133652309 @default.
- W2038748154 cites W2141674158 @default.
- W2038748154 cites W2161603147 @default.
- W2038748154 cites W2162299988 @default.
- W2038748154 cites W2167840994 @default.
- W2038748154 cites W2282701858 @default.
- W2038748154 cites W2319708874 @default.
- W2038748154 cites W4205765964 @default.
- W2038748154 cites W4299119409 @default.
- W2038748154 doi "https://doi.org/10.1186/s12879-014-0701-2" @default.
- W2038748154 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4297378" @default.
- W2038748154 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25539905" @default.
- W2038748154 hasPublicationYear "2014" @default.
- W2038748154 type Work @default.
- W2038748154 sameAs 2038748154 @default.
- W2038748154 citedByCount "8" @default.
- W2038748154 countsByYear W20387481542015 @default.
- W2038748154 countsByYear W20387481542016 @default.
- W2038748154 countsByYear W20387481542018 @default.
- W2038748154 countsByYear W20387481542020 @default.
- W2038748154 countsByYear W20387481542022 @default.
- W2038748154 countsByYear W20387481542023 @default.
- W2038748154 crossrefType "journal-article" @default.
- W2038748154 hasAuthorship W2038748154A5009761215 @default.
- W2038748154 hasAuthorship W2038748154A5034642104 @default.
- W2038748154 hasAuthorship W2038748154A5039572099 @default.
- W2038748154 hasAuthorship W2038748154A5052407990 @default.
- W2038748154 hasAuthorship W2038748154A5060490422 @default.
- W2038748154 hasAuthorship W2038748154A5061842330 @default.
- W2038748154 hasBestOaLocation W20387481541 @default.
- W2038748154 hasConcept C119060515 @default.
- W2038748154 hasConcept C126322002 @default.
- W2038748154 hasConcept C142462285 @default.
- W2038748154 hasConcept C187212893 @default.
- W2038748154 hasConcept C197934379 @default.
- W2038748154 hasConcept C203014093 @default.
- W2038748154 hasConcept C2779130552 @default.
- W2038748154 hasConcept C2993143319 @default.
- W2038748154 hasConcept C3013748606 @default.
- W2038748154 hasConcept C71924100 @default.
- W2038748154 hasConceptScore W2038748154C119060515 @default.
- W2038748154 hasConceptScore W2038748154C126322002 @default.
- W2038748154 hasConceptScore W2038748154C142462285 @default.
- W2038748154 hasConceptScore W2038748154C187212893 @default.
- W2038748154 hasConceptScore W2038748154C197934379 @default.
- W2038748154 hasConceptScore W2038748154C203014093 @default.
- W2038748154 hasConceptScore W2038748154C2779130552 @default.
- W2038748154 hasConceptScore W2038748154C2993143319 @default.
- W2038748154 hasConceptScore W2038748154C3013748606 @default.
- W2038748154 hasConceptScore W2038748154C71924100 @default.
- W2038748154 hasIssue "1" @default.
- W2038748154 hasLocation W20387481541 @default.
- W2038748154 hasLocation W20387481542 @default.
- W2038748154 hasLocation W20387481543 @default.
- W2038748154 hasLocation W20387481544 @default.
- W2038748154 hasOpenAccess W2038748154 @default.
- W2038748154 hasPrimaryLocation W20387481541 @default.
- W2038748154 hasRelatedWork W2020624883 @default.
- W2038748154 hasRelatedWork W2047555579 @default.
- W2038748154 hasRelatedWork W2048864317 @default.
- W2038748154 hasRelatedWork W2105776266 @default.
- W2038748154 hasRelatedWork W2140384375 @default.
- W2038748154 hasRelatedWork W2603130550 @default.
- W2038748154 hasRelatedWork W4206018297 @default.
- W2038748154 hasRelatedWork W4250316256 @default.
- W2038748154 hasRelatedWork W4300351178 @default.
- W2038748154 hasRelatedWork W4301807426 @default.
- W2038748154 hasVolume "14" @default.
- W2038748154 isParatext "false" @default.
- W2038748154 isRetracted "false" @default.
- W2038748154 magId "2038748154" @default.
- W2038748154 workType "article" @default.