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• W2038748372 abstract "This study addresses the problem of antibiotic resistance in adhesive, biomaterial-centred infections. It is suggested that this anionic, extracapsular, polysaccharide slime produced by bacteria protects them from antibiotics and sequesters critical ions from the surface of biomaterials. Biofilm-enclosed bacteria on the surface of stainless steel substrata in a test chamber were challenged with incremental levels of tobramycin. In this setting, the minimum inhibitory concentration and minimum bactericidal level of tobramycin for Staphylococcus epidermis were well above normal." @default.
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• W2038748372 date "1987-11-01" @default.
• W2038748372 modified "2023-10-14" @default.
• W2038748372 title "Adhesive colonization of biomaterials and antibiotic resistance" @default.
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• W2038748372 doi "https://doi.org/10.1016/0142-9612(87)90077-9" @default.
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