Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038832783> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2038832783 endingPage "65" @default.
- W2038832783 startingPage "61" @default.
- W2038832783 abstract "An electrochemical in vivo flow-injection system with an on-line microdialysis sampling is proposed for the simultaneous monitoring of l-lactate and glucose in rat brain. In the first stage of the operation, the dialysate from the microdialysis probe is delivered to a sample loop of the six-way autoinjector by perfusing Ringer’s solution for 80 s at 5 µl min–1. In the second stage, the dialysate collected in the sample loop is automatically injected for 10 s into the flow-injection line. Injected dialysate is split into two streams and two portions pass through two channels with two different immobilized enzyme reactors (glucose oxidase and lactate oxidase immobilized reactors) to produce hydrogen peroxide from glucose and l-lactate in the dialysate. After a subsequent confluence of the streams, produced hydrogen peroxide can be detected amperometrically at a downstream poly(1,2-diaminobenzene) film-coated platinum electrode, without any interference from oxidizable species and proteins present in the dialysate. Because each channel has a different residence time, two peaks are obtained. The first peak corresponds to l-lactate and the second peak to glucose. The peak current is linearly related to the concentrations of l-lactate between 0.2 and 10 mM and glucose between 0.1 and 20 mM. The present method can be successfully applied to the simultaneous in vivo monitoring of l-lactate and glucose in rat brain. The analytical speed is 45 dialysates h–1." @default.
- W2038832783 created "2016-06-24" @default.
- W2038832783 creator A5048396593 @default.
- W2038832783 creator A5065867426 @default.
- W2038832783 creator A5073368369 @default.
- W2038832783 creator A5084634593 @default.
- W2038832783 date "2003-01-01" @default.
- W2038832783 modified "2023-10-04" @default.
- W2038832783 title "Simultaneous Determination of Glucose and l-Lactate in Rat Brain by an Electrochemical in vivo Flow-Injection System with an On-line Microdialysis Sampling" @default.
- W2038832783 cites W1979387706 @default.
- W2038832783 cites W1982000903 @default.
- W2038832783 cites W1989562548 @default.
- W2038832783 cites W1989918294 @default.
- W2038832783 cites W1993637583 @default.
- W2038832783 cites W2000544932 @default.
- W2038832783 cites W2001542494 @default.
- W2038832783 cites W2001931352 @default.
- W2038832783 cites W2012389161 @default.
- W2038832783 cites W2015165486 @default.
- W2038832783 cites W2017503273 @default.
- W2038832783 cites W2019208876 @default.
- W2038832783 cites W2021819567 @default.
- W2038832783 cites W2022080565 @default.
- W2038832783 cites W2027248446 @default.
- W2038832783 cites W2031139568 @default.
- W2038832783 cites W2054931155 @default.
- W2038832783 cites W2066266085 @default.
- W2038832783 cites W2074083279 @default.
- W2038832783 cites W2093434531 @default.
- W2038832783 cites W2095360471 @default.
- W2038832783 cites W2144499458 @default.
- W2038832783 cites W2146533847 @default.
- W2038832783 cites W2164860619 @default.
- W2038832783 doi "https://doi.org/10.2116/analsci.19.61" @default.
- W2038832783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12558025" @default.
- W2038832783 hasPublicationYear "2003" @default.
- W2038832783 type Work @default.
- W2038832783 sameAs 2038832783 @default.
- W2038832783 citedByCount "18" @default.
- W2038832783 countsByYear W20388327832012 @default.
- W2038832783 countsByYear W20388327832013 @default.
- W2038832783 countsByYear W20388327832014 @default.
- W2038832783 crossrefType "journal-article" @default.
- W2038832783 hasAuthorship W2038832783A5048396593 @default.
- W2038832783 hasAuthorship W2038832783A5065867426 @default.
- W2038832783 hasAuthorship W2038832783A5073368369 @default.
- W2038832783 hasAuthorship W2038832783A5084634593 @default.
- W2038832783 hasConcept C150903083 @default.
- W2038832783 hasConcept C160756335 @default.
- W2038832783 hasConcept C185592680 @default.
- W2038832783 hasConcept C207001950 @default.
- W2038832783 hasConcept C2777197210 @default.
- W2038832783 hasConcept C28406088 @default.
- W2038832783 hasConcept C43617362 @default.
- W2038832783 hasConcept C50156730 @default.
- W2038832783 hasConcept C533411734 @default.
- W2038832783 hasConcept C55493867 @default.
- W2038832783 hasConcept C86803240 @default.
- W2038832783 hasConceptScore W2038832783C150903083 @default.
- W2038832783 hasConceptScore W2038832783C160756335 @default.
- W2038832783 hasConceptScore W2038832783C185592680 @default.
- W2038832783 hasConceptScore W2038832783C207001950 @default.
- W2038832783 hasConceptScore W2038832783C2777197210 @default.
- W2038832783 hasConceptScore W2038832783C28406088 @default.
- W2038832783 hasConceptScore W2038832783C43617362 @default.
- W2038832783 hasConceptScore W2038832783C50156730 @default.
- W2038832783 hasConceptScore W2038832783C533411734 @default.
- W2038832783 hasConceptScore W2038832783C55493867 @default.
- W2038832783 hasConceptScore W2038832783C86803240 @default.
- W2038832783 hasIssue "1" @default.
- W2038832783 hasLocation W20388327831 @default.
- W2038832783 hasLocation W20388327832 @default.
- W2038832783 hasOpenAccess W2038832783 @default.
- W2038832783 hasPrimaryLocation W20388327831 @default.
- W2038832783 hasRelatedWork W1972861168 @default.
- W2038832783 hasRelatedWork W1987090948 @default.
- W2038832783 hasRelatedWork W1994137655 @default.
- W2038832783 hasRelatedWork W1998727627 @default.
- W2038832783 hasRelatedWork W2030412365 @default.
- W2038832783 hasRelatedWork W2045287968 @default.
- W2038832783 hasRelatedWork W2096837492 @default.
- W2038832783 hasRelatedWork W2097531349 @default.
- W2038832783 hasRelatedWork W2952678824 @default.
- W2038832783 hasRelatedWork W2952785262 @default.
- W2038832783 hasVolume "19" @default.
- W2038832783 isParatext "false" @default.
- W2038832783 isRetracted "false" @default.
- W2038832783 magId "2038832783" @default.
- W2038832783 workType "article" @default.