FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038861601> ?p ?o ?g. }

• W2038861601 abstract "Successful stem cell transplantation depends on cell dose, and this is particularly true for placental/cord blood transplantation in which it has been clearly shown that both the success of engraftment as well as the speed of white cell and platelet recovery are dependent on the nucleated cell dose in the graft. Thus, if stem cell numbers could be increased, the speed as well as the likelihood of engraftment might be improved. We studied the effect of two different cytokine combinations--kit ligand (KL), interleukin-3 (IL-3), and Flt-3 ligand supplemented with thrombopoietin and IL-11 (combination 1) or granulocyte/macrophage colony-stimulating factor (GM-CSF) and G-CSF (combination 2)--for their ability to affect speed and extent of engraftment using limited numbers (5 x 10(4)) of murine bone marrow (BM) light-density (LD) cells or their progeny expanded ex vivo in the presence one or the other cytokine combination for 6 days. With combination 1, we found that speed of platelet recovery was enhanced, but at the expense of white blood cell (WBC) recovery and percent donor engraftment. Furthermore, the cytokine combination that best maintained donor engraftment, combination 2, did so at the expense of platelet recovery. In no case was percent donor engraftment improved over 5 x 10(4) unmanipulated LD BM cells. These results are consistent with the interpretation that immediate recovery of blood cells of different lineages and longterm donor engraftment are separate functions that can be influenced by the choice of cytokines used during the ex vivo expansion process." @default.
• W2038861601 created "2016-06-24" @default.
• W2038861601 creator A5003621767 @default.
• W2038861601 creator A5022048944 @default.
• W2038861601 creator A5045177793 @default.
• W2038861601 creator A5068924278 @default.
• W2038861601 creator A5088165560 @default.
• W2038861601 date "2005-10-01" @default.
• W2038861601 modified "2023-10-14" @default.
• W2038861601 title "The Rate of Marrow Recovery and Extent of Donor Engraftment Following Transplantation of Ex Vivo–Expanded Bone Marrow Cells Are Independently Influenced by the Cytokines Used for Expansion" @default.
• W2038861601 cites W109001291 @default.
• W2038861601 cites W1589781515 @default.
• W2038861601 cites W173907651 @default.
• W2038861601 cites W18584205 @default.
• W2038861601 cites W1906638117 @default.
• W2038861601 cites W1965613868 @default.
• W2038861601 cites W1969684689 @default.
• W2038861601 cites W1969835384 @default.
• W2038861601 cites W1977253353 @default.
• W2038861601 cites W1988576340 @default.
• W2038861601 cites W2009658831 @default.
• W2038861601 cites W2016632882 @default.
• W2038861601 cites W2017709719 @default.
• W2038861601 cites W2021050536 @default.
• W2038861601 cites W2032594449 @default.
• W2038861601 cites W2033244045 @default.
• W2038861601 cites W2037741965 @default.
• W2038861601 cites W2038672919 @default.
• W2038861601 cites W2042049564 @default.
• W2038861601 cites W2043591248 @default.
• W2038861601 cites W2054031422 @default.
• W2038861601 cites W2080008757 @default.
• W2038861601 cites W2081443875 @default.
• W2038861601 cites W2085516849 @default.
• W2038861601 cites W2092015913 @default.
• W2038861601 cites W2095999343 @default.
• W2038861601 cites W2118453722 @default.
• W2038861601 cites W2120208604 @default.
• W2038861601 cites W2123018692 @default.
• W2038861601 cites W2124037257 @default.
• W2038861601 cites W2129321368 @default.
• W2038861601 cites W2135067231 @default.
• W2038861601 cites W2139485932 @default.
• W2038861601 cites W2143635337 @default.
• W2038861601 cites W2144290143 @default.
• W2038861601 cites W2147864074 @default.
• W2038861601 cites W2149953201 @default.
• W2038861601 cites W2159310677 @default.
• W2038861601 cites W2160531849 @default.
• W2038861601 cites W2161290044 @default.
• W2038861601 cites W2162833666 @default.
• W2038861601 cites W2167020774 @default.
• W2038861601 cites W2265597917 @default.
• W2038861601 cites W2270550164 @default.
• W2038861601 cites W2272909078 @default.
• W2038861601 cites W2280798535 @default.
• W2038861601 cites W228431643 @default.
• W2038861601 cites W2292632382 @default.
• W2038861601 cites W2314064520 @default.
• W2038861601 cites W2322070115 @default.
• W2038861601 cites W2337839049 @default.
• W2038861601 cites W2395517345 @default.
• W2038861601 cites W2396977997 @default.
• W2038861601 cites W2401650380 @default.
• W2038861601 cites W2405719302 @default.
• W2038861601 cites W2412909497 @default.
• W2038861601 cites W2416720626 @default.
• W2038861601 cites W2419445187 @default.
• W2038861601 cites W2463077989 @default.
• W2038861601 cites W328302314 @default.
• W2038861601 cites W329662528 @default.
• W2038861601 cites W65051584 @default.
• W2038861601 cites W652428510 @default.
• W2038861601 doi "https://doi.org/10.1089/scd.2005.14.564" @default.
• W2038861601 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16305341" @default.
• W2038861601 hasPublicationYear "2005" @default.
• W2038861601 type Work @default.
• W2038861601 sameAs 2038861601 @default.
• W2038861601 citedByCount "4" @default.
• W2038861601 countsByYear W20388616012013 @default.
• W2038861601 crossrefType "journal-article" @default.
• W2038861601 hasAuthorship W2038861601A5003621767 @default.
• W2038861601 hasAuthorship W2038861601A5022048944 @default.
• W2038861601 hasAuthorship W2038861601A5045177793 @default.
• W2038861601 hasAuthorship W2038861601A5068924278 @default.
• W2038861601 hasAuthorship W2038861601A5088165560 @default.
• W2038861601 hasConcept C109159458 @default.
• W2038861601 hasConcept C126322002 @default.
• W2038861601 hasConcept C150903083 @default.
• W2038861601 hasConcept C16685009 @default.
• W2038861601 hasConcept C2022786 @default.
• W2038861601 hasConcept C203014093 @default.
• W2038861601 hasConcept C207001950 @default.
• W2038861601 hasConcept C26291073 @default.
• W2038861601 hasConcept C2777478134 @default.
• W2038861601 hasConcept C2777863708 @default.
• W2038861601 hasConcept C2778690821 @default.
• W2038861601 hasConcept C2780007613 @default.
• W2038861601 hasConcept C2780914630 @default.
• W2038861601 hasConcept C28328180 @default.

• next