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- W2038897445 abstract "5-Lipoxygenase (5-LO) catalyses the two initial steps in the biosynthesis of leukotrienes, a group of inflammatory lipid mediators derived from arachidonic acid. An increased level of leukotrienes is associated with chronic inflammatory diseases such as asthma or atherosclerosis. In this MiniReview, we focus on recent findings regarding alternative splice variants of 5-LO with a special emphasis on two potential protein isoforms expressed in human B-lymphocytes which might be of interest as new drug targets." @default.
- W2038897445 created "2016-06-24" @default.
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- W2038897445 date "2013-09-10" @default.
- W2038897445 modified "2023-10-14" @default.
- W2038897445 title "5-Lipoxygenase mRNA and Protein Isoforms" @default.
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- W2038897445 doi "https://doi.org/10.1111/bcpt.12115" @default.
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