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• W2038962843 abstract "Aim: The aim was to statistically model the degree of fear of hypoglycaemia experienced by people with diabetes, and then model the resulting change in health-related utility associated with differing severity and frequency of hypoglycaemia.Methods: The study used pooled data from two previous postal surveys among subjects with confirmed diabetes conducted in Cardiff, UK (n = 1305 responses). The fear of hypoglycaemia was characterised using the Hypoglycaemia Fear Survey (HFS [eight question worry sub-scale only]), and health-related utility using the EQ5Dindex. The data were then analysed using univariate and multivariate analysis.Results: Following detailed preliminary analysis, a two-stage approach was used since fear was important when estimating the EQ5Dindex. Fear was then modelled as a function of the severity and frequency of hypoglycaemia while controlling for other factors such as diabetes-related complications. Each severe hypoglycaemic event resulted in a change of 5.881 units on the HFS. One or more symptomatic hypoglycaemic events over the same period results in a corresponding change of 1.773 units on the HFS. A 1 unit increase on the HFS results in a 0.008 unit decrease on the EQ5Dindex.Conclusion: While controlling for other factors, the fear of hypoglycaemia was an important determinant of health-related utility. The magnitude of fear of hypoglycaemia was associated with the severity and frequency of hypoglycaemia. Hypoglycaemia was associated with a considerable decrement in health-related utility as a function of increased fear. Measures should be taken to minimise the severity and frequency of hypoglycaemia." @default.
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• W2038962843 date "2006-06-28" @default.
• W2038962843 modified "2023-10-11" @default.
• W2038962843 title "Multivariate models of health-related utility and the fear of hypoglycaemia in people with diabetes" @default.
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• W2038962843 doi "https://doi.org/10.1185/030079906x115757" @default.
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