Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038971761> ?p ?o ?g. }
- W2038971761 endingPage "1261" @default.
- W2038971761 startingPage "1249" @default.
- W2038971761 abstract "An insoluble white substance was prepared from extracts of eggshells of Aedes aegypti, the yellow fever mosquito and dengue vector. Its infrared and proton NMR spectra were similar to that of standard commercial chitin. This putative chitin-like material, also obtained from ovaries, newly laid and dark eggs, was hydrolyzed in acid and a major product was identified by HPLC to be glucosamine. The eggshell acid hydrolysate was also analyzed by ESI-MS and an ion identical to a glucosamine monoprotonated species was detected. The presence of chitin was also analyzed during different developmental stages of the ovary using a fluorescent microscopy technique and probes specific for chitin. The results showed that a chitin-like material accumulates in oocytes during oogenesis. Streptomyces griseus chitinase pre-treatment of oocytes greatly reduced the chitin-derived fluorescence. Chitinase activity was detected in newborn larvae and eggs prior to hatching. Feeding experiments indicated that the chitin synthesis inhibitor lufenuron inhibited chitin synthesis, either when mosquitoes were allowed to feed directly on lufenuron-treated chickens or when an artificial feeding system was used. Lufenuron inhibited egg hatch, larval development and reduced mosquito viability. These data demonstrate for the first time that (1) a chitin-like material is present in A. aegypti eggs, ovaries and eggshells; (2) a chitin synthesis inhibitor can be used to inhibit mosquito oogenesis; and (3) chitin synthesis inhibitors have potential for controlling mosquito populations." @default.
- W2038971761 created "2016-06-24" @default.
- W2038971761 creator A5003492646 @default.
- W2038971761 creator A5013088482 @default.
- W2038971761 creator A5026552662 @default.
- W2038971761 creator A5029246531 @default.
- W2038971761 creator A5031731499 @default.
- W2038971761 creator A5032693800 @default.
- W2038971761 creator A5035380581 @default.
- W2038971761 creator A5042552258 @default.
- W2038971761 creator A5046012568 @default.
- W2038971761 creator A5078051461 @default.
- W2038971761 creator A5079434777 @default.
- W2038971761 creator A5086046793 @default.
- W2038971761 date "2007-12-01" @default.
- W2038971761 modified "2023-10-09" @default.
- W2038971761 title "A chitin-like component in Aedes aegypti eggshells, eggs and ovaries" @default.
- W2038971761 cites W103430187 @default.
- W2038971761 cites W1233367020 @default.
- W2038971761 cites W1238880271 @default.
- W2038971761 cites W1963571695 @default.
- W2038971761 cites W1963749283 @default.
- W2038971761 cites W1968834637 @default.
- W2038971761 cites W1981703909 @default.
- W2038971761 cites W1982192077 @default.
- W2038971761 cites W1983367189 @default.
- W2038971761 cites W1984961515 @default.
- W2038971761 cites W1991636010 @default.
- W2038971761 cites W1992364486 @default.
- W2038971761 cites W1995852300 @default.
- W2038971761 cites W1999357642 @default.
- W2038971761 cites W2009526805 @default.
- W2038971761 cites W2010481484 @default.
- W2038971761 cites W2011762606 @default.
- W2038971761 cites W2013102733 @default.
- W2038971761 cites W2016572065 @default.
- W2038971761 cites W2018098995 @default.
- W2038971761 cites W2018759681 @default.
- W2038971761 cites W2019427959 @default.
- W2038971761 cites W2022245501 @default.
- W2038971761 cites W2023738859 @default.
- W2038971761 cites W2023882040 @default.
- W2038971761 cites W2024929963 @default.
- W2038971761 cites W2030428720 @default.
- W2038971761 cites W2035544799 @default.
- W2038971761 cites W2036615634 @default.
- W2038971761 cites W2036746828 @default.
- W2038971761 cites W2042490073 @default.
- W2038971761 cites W2043013497 @default.
- W2038971761 cites W2043535323 @default.
- W2038971761 cites W2048616259 @default.
- W2038971761 cites W2053139374 @default.
- W2038971761 cites W2060502532 @default.
- W2038971761 cites W2062263564 @default.
- W2038971761 cites W2064534229 @default.
- W2038971761 cites W2072435343 @default.
- W2038971761 cites W2073292063 @default.
- W2038971761 cites W2073915598 @default.
- W2038971761 cites W2093644661 @default.
- W2038971761 cites W2109293107 @default.
- W2038971761 cites W2115157017 @default.
- W2038971761 cites W2131308828 @default.
- W2038971761 cites W2132185905 @default.
- W2038971761 cites W2140016500 @default.
- W2038971761 cites W2140303509 @default.
- W2038971761 cites W2152311269 @default.
- W2038971761 cites W2154912073 @default.
- W2038971761 cites W2155284530 @default.
- W2038971761 cites W2156781216 @default.
- W2038971761 cites W2172567593 @default.
- W2038971761 cites W2174053354 @default.
- W2038971761 cites W2177350294 @default.
- W2038971761 cites W2308911018 @default.
- W2038971761 cites W2327846234 @default.
- W2038971761 cites W2328459205 @default.
- W2038971761 cites W2332768911 @default.
- W2038971761 cites W2414173056 @default.
- W2038971761 cites W56808011 @default.
- W2038971761 cites W2584460801 @default.
- W2038971761 doi "https://doi.org/10.1016/j.ibmb.2007.07.017" @default.
- W2038971761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17967344" @default.
- W2038971761 hasPublicationYear "2007" @default.
- W2038971761 type Work @default.
- W2038971761 sameAs 2038971761 @default.
- W2038971761 citedByCount "88" @default.
- W2038971761 countsByYear W20389717612012 @default.
- W2038971761 countsByYear W20389717612013 @default.
- W2038971761 countsByYear W20389717612014 @default.
- W2038971761 countsByYear W20389717612015 @default.
- W2038971761 countsByYear W20389717612016 @default.
- W2038971761 countsByYear W20389717612017 @default.
- W2038971761 countsByYear W20389717612018 @default.
- W2038971761 countsByYear W20389717612019 @default.
- W2038971761 countsByYear W20389717612020 @default.
- W2038971761 countsByYear W20389717612021 @default.
- W2038971761 countsByYear W20389717612022 @default.
- W2038971761 countsByYear W20389717612023 @default.
- W2038971761 crossrefType "journal-article" @default.