FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2038973724> ?p ?o ?g. }

• W2038973724 endingPage "240" @default.
• W2038973724 startingPage "234" @default.
• W2038973724 abstract "The antimicrobial peptide PMAP-36 exists as a homodimer stabilized by an intermolecular disulfide bridge. The dimer of PMAP-36 exhibits a potent and rapid microbicidal activity against a wide spectrum of microorganisms. The gene encoding the antiparallel dimer (PMAP-36)₂ was designed and codon-optimized according to bias of <i>Pichia pastoris</i>. The gene was then expressed in the <i>P. pastoris</i> strain GS115. The concentration of the recombinant product reached 106 mg/l. In vitro activity assays indicated that the recombinant peptide showed antimicrobial activities against Gram-positive and Gram-negative bacteria but did not cause hemolysis of chicken erythrocytes. Subsequently, 120 7-day-old male Arbor Acres broilers were used to evaluate the in vivo activities of the peptide. A prophylactic dose of ciprofloxacin lactate was supplemented as the control. The results showed that recombinant (PMAP-36)₂ significantly increased the serum IgM content of the birds (p < 0.05). The recombinant peptide significantly increased the amounts of <i>Bifidobacterium</i> and decreased the amount of <i>Escherichia coli</i> cells in the ceca of the experimental birds (p < 0.05). The results obtained in the present study indicate that the recombinant (PMAP-36)₂ has a potent in vitro and in vivo activity and can be used as an alternative to antibiotic treatment." @default.
• W2038973724 created "2016-06-24" @default.
• W2038973724 creator A5010144767 @default.
• W2038973724 creator A5049341927 @default.
• W2038973724 creator A5073001021 @default.
• W2038973724 creator A5077298025 @default.
• W2038973724 creator A5078716858 @default.
• W2038973724 creator A5089207221 @default.
• W2038973724 date "2014-01-01" @default.
• W2038973724 modified "2023-10-18" @default.
• W2038973724 title "In vitro and in vivo Activity of the Dimer of PMAP-36 Expressed in <b><i>Pichia pastoris</i></b>" @default.
• W2038973724 cites W1970848653 @default.
• W2038973724 cites W1977158240 @default.
• W2038973724 cites W1984693521 @default.
• W2038973724 cites W1990603865 @default.
• W2038973724 cites W1993326358 @default.
• W2038973724 cites W1993819561 @default.
• W2038973724 cites W2000820802 @default.
• W2038973724 cites W2011605146 @default.
• W2038973724 cites W2014111920 @default.
• W2038973724 cites W2019018366 @default.
• W2038973724 cites W2025092559 @default.
• W2038973724 cites W2032520233 @default.
• W2038973724 cites W2036414757 @default.
• W2038973724 cites W2051142131 @default.
• W2038973724 cites W2054602599 @default.
• W2038973724 cites W2060486005 @default.
• W2038973724 cites W2060943210 @default.
• W2038973724 cites W2063325790 @default.
• W2038973724 cites W2065497011 @default.
• W2038973724 cites W2067932958 @default.
• W2038973724 cites W2068894345 @default.
• W2038973724 cites W2071114997 @default.
• W2038973724 cites W2077526264 @default.
• W2038973724 cites W2081845133 @default.
• W2038973724 cites W2089090464 @default.
• W2038973724 cites W2089559505 @default.
• W2038973724 cites W2102577519 @default.
• W2038973724 cites W2117938779 @default.
• W2038973724 cites W2135112724 @default.
• W2038973724 cites W2138443028 @default.
• W2038973724 cites W2144368486 @default.
• W2038973724 cites W2159861471 @default.
• W2038973724 cites W2160230157 @default.
• W2038973724 cites W2161560597 @default.
• W2038973724 cites W2164163739 @default.
• W2038973724 doi "https://doi.org/10.1159/000365572" @default.
• W2038973724 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25196715" @default.
• W2038973724 hasPublicationYear "2014" @default.
• W2038973724 type Work @default.
• W2038973724 sameAs 2038973724 @default.
• W2038973724 citedByCount "6" @default.
• W2038973724 countsByYear W20389737242018 @default.
• W2038973724 countsByYear W20389737242020 @default.
• W2038973724 countsByYear W20389737242021 @default.
• W2038973724 crossrefType "journal-article" @default.
• W2038973724 hasAuthorship W2038973724A5010144767 @default.
• W2038973724 hasAuthorship W2038973724A5049341927 @default.
• W2038973724 hasAuthorship W2038973724A5073001021 @default.
• W2038973724 hasAuthorship W2038973724A5077298025 @default.
• W2038973724 hasAuthorship W2038973724A5078716858 @default.
• W2038973724 hasAuthorship W2038973724A5089207221 @default.
• W2038973724 hasConcept C104317684 @default.
• W2038973724 hasConcept C150903083 @default.
• W2038973724 hasConcept C153911025 @default.
• W2038973724 hasConcept C185592680 @default.
• W2038973724 hasConcept C202751555 @default.
• W2038973724 hasConcept C207001950 @default.
• W2038973724 hasConcept C2779281246 @default.
• W2038973724 hasConcept C2781372317 @default.
• W2038973724 hasConcept C40767141 @default.
• W2038973724 hasConcept C547475151 @default.
• W2038973724 hasConcept C55493867 @default.
• W2038973724 hasConcept C86803240 @default.
• W2038973724 hasConceptScore W2038973724C104317684 @default.
• W2038973724 hasConceptScore W2038973724C150903083 @default.
• W2038973724 hasConceptScore W2038973724C153911025 @default.
• W2038973724 hasConceptScore W2038973724C185592680 @default.
• W2038973724 hasConceptScore W2038973724C202751555 @default.
• W2038973724 hasConceptScore W2038973724C207001950 @default.
• W2038973724 hasConceptScore W2038973724C2779281246 @default.
• W2038973724 hasConceptScore W2038973724C2781372317 @default.
• W2038973724 hasConceptScore W2038973724C40767141 @default.
• W2038973724 hasConceptScore W2038973724C547475151 @default.
• W2038973724 hasConceptScore W2038973724C55493867 @default.
• W2038973724 hasConceptScore W2038973724C86803240 @default.
• W2038973724 hasIssue "4" @default.
• W2038973724 hasLocation W20389737241 @default.
• W2038973724 hasLocation W20389737242 @default.
• W2038973724 hasOpenAccess W2038973724 @default.
• W2038973724 hasPrimaryLocation W20389737241 @default.
• W2038973724 hasRelatedWork W1998117828 @default.
• W2038973724 hasRelatedWork W2016628627 @default.
• W2038973724 hasRelatedWork W2043576708 @default.
• W2038973724 hasRelatedWork W2347635724 @default.
• W2038973724 hasRelatedWork W2359519236 @default.
• W2038973724 hasRelatedWork W2362323597 @default.
• W2038973724 hasRelatedWork W2362947827 @default.

• next