Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039037884> ?p ?o ?g. }
- W2039037884 endingPage "572" @default.
- W2039037884 startingPage "568" @default.
- W2039037884 abstract "Ran, a small Ras-like GTP-binding nuclear protein, plays a key role in modulation of various cellular signaling events including the cell cycle. This study shows that a cellular redox agent (nitrogen dioxide) facilitates Ran guanine nucleotide dissociation, and identifies a unique Ran redox architecture involved in that process. Sequence analysis suggests that Dexras1 and Rhes GTPases also possess the Ran redox architecture. As Ran releases an intact nucleotide, the redox regulation mechanism of Ran is likely to differ from the radical-based guanine nucleotide modification mechanism suggested for Ras and Rho GTPases. These results provide a mechanistic reason for the previously observed oxidative stress-induced perturbation of the Ran-mediated nuclear import, and suggest that oxidative stress could be a factor in the regulation of cell signal transduction pathways associated with Ran." @default.
- W2039037884 created "2016-06-24" @default.
- W2039037884 creator A5087949495 @default.
- W2039037884 date "2008-11-01" @default.
- W2039037884 modified "2023-09-23" @default.
- W2039037884 title "Redox regulation of Ran GTPase" @default.
- W2039037884 cites W146469911 @default.
- W2039037884 cites W1484823281 @default.
- W2039037884 cites W1965954844 @default.
- W2039037884 cites W1967162316 @default.
- W2039037884 cites W1967902241 @default.
- W2039037884 cites W1972989329 @default.
- W2039037884 cites W1973317841 @default.
- W2039037884 cites W1978932179 @default.
- W2039037884 cites W1984680858 @default.
- W2039037884 cites W1988862154 @default.
- W2039037884 cites W1990790970 @default.
- W2039037884 cites W1992778133 @default.
- W2039037884 cites W2014307956 @default.
- W2039037884 cites W2025993499 @default.
- W2039037884 cites W2027583173 @default.
- W2039037884 cites W2032839609 @default.
- W2039037884 cites W2037574965 @default.
- W2039037884 cites W2041539035 @default.
- W2039037884 cites W2044681890 @default.
- W2039037884 cites W2047627595 @default.
- W2039037884 cites W2048798282 @default.
- W2039037884 cites W2049921064 @default.
- W2039037884 cites W2057204732 @default.
- W2039037884 cites W2061260890 @default.
- W2039037884 cites W2063650074 @default.
- W2039037884 cites W2064488173 @default.
- W2039037884 cites W2069177549 @default.
- W2039037884 cites W2073803432 @default.
- W2039037884 cites W2077180958 @default.
- W2039037884 cites W2077190796 @default.
- W2039037884 cites W2089780753 @default.
- W2039037884 cites W2091169894 @default.
- W2039037884 cites W2108442683 @default.
- W2039037884 cites W2108582098 @default.
- W2039037884 cites W2121422799 @default.
- W2039037884 cites W2123716423 @default.
- W2039037884 cites W2154708902 @default.
- W2039037884 cites W2167843940 @default.
- W2039037884 doi "https://doi.org/10.1016/j.bbrc.2008.09.016" @default.
- W2039037884 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18796295" @default.
- W2039037884 hasPublicationYear "2008" @default.
- W2039037884 type Work @default.
- W2039037884 sameAs 2039037884 @default.
- W2039037884 citedByCount "15" @default.
- W2039037884 countsByYear W20390378842012 @default.
- W2039037884 countsByYear W20390378842013 @default.
- W2039037884 countsByYear W20390378842015 @default.
- W2039037884 countsByYear W20390378842016 @default.
- W2039037884 crossrefType "journal-article" @default.
- W2039037884 hasAuthorship W2039037884A5087949495 @default.
- W2039037884 hasConcept C118716 @default.
- W2039037884 hasConcept C126619667 @default.
- W2039037884 hasConcept C160704184 @default.
- W2039037884 hasConcept C181199279 @default.
- W2039037884 hasConcept C185592680 @default.
- W2039037884 hasConcept C207332259 @default.
- W2039037884 hasConcept C2780114586 @default.
- W2039037884 hasConcept C2780298669 @default.
- W2039037884 hasConcept C2780723820 @default.
- W2039037884 hasConcept C2781335528 @default.
- W2039037884 hasConcept C55493867 @default.
- W2039037884 hasConcept C59157529 @default.
- W2039037884 hasConcept C62478195 @default.
- W2039037884 hasConcept C86803240 @default.
- W2039037884 hasConcept C95444343 @default.
- W2039037884 hasConceptScore W2039037884C118716 @default.
- W2039037884 hasConceptScore W2039037884C126619667 @default.
- W2039037884 hasConceptScore W2039037884C160704184 @default.
- W2039037884 hasConceptScore W2039037884C181199279 @default.
- W2039037884 hasConceptScore W2039037884C185592680 @default.
- W2039037884 hasConceptScore W2039037884C207332259 @default.
- W2039037884 hasConceptScore W2039037884C2780114586 @default.
- W2039037884 hasConceptScore W2039037884C2780298669 @default.
- W2039037884 hasConceptScore W2039037884C2780723820 @default.
- W2039037884 hasConceptScore W2039037884C2781335528 @default.
- W2039037884 hasConceptScore W2039037884C55493867 @default.
- W2039037884 hasConceptScore W2039037884C59157529 @default.
- W2039037884 hasConceptScore W2039037884C62478195 @default.
- W2039037884 hasConceptScore W2039037884C86803240 @default.
- W2039037884 hasConceptScore W2039037884C95444343 @default.
- W2039037884 hasIssue "3" @default.
- W2039037884 hasLocation W20390378841 @default.
- W2039037884 hasLocation W20390378842 @default.
- W2039037884 hasOpenAccess W2039037884 @default.
- W2039037884 hasPrimaryLocation W20390378841 @default.
- W2039037884 hasRelatedWork W1553856836 @default.
- W2039037884 hasRelatedWork W1902070349 @default.
- W2039037884 hasRelatedWork W2039037884 @default.
- W2039037884 hasRelatedWork W2042535043 @default.
- W2039037884 hasRelatedWork W2056698109 @default.
- W2039037884 hasRelatedWork W2065619679 @default.
- W2039037884 hasRelatedWork W2080061119 @default.