Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039044218> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2039044218 abstract "Abstract Exposure of adult rats to 0.8 ppm ozone enhanced collagen synthesis in the lungs. Collagen synthesis was studied by estimating hydroxyproline (Hyp) content and by following the activity of prolyl hydroxylase (PH), a crucial enzyme in the pathway of collagen biosynthesis. In the early phases (1–2 day) of ozone-induced injury, PH activity was increased twofold over control values and the amount of collagen synthesized (as estimated by Hyp formation) was double the amount of non-collagenous protein synthesized. This resulted, by the third day, in a significant increase (29%) in total lung collagen. In the later stages of the injury (3–7 day), however, increases in PH activity were more gradual, approaching 2.7 times control levels at the end of the 7-day exposure period. The synthesis of non-collagenous protein during this period increased steadily and by the 7th day the ratio of the amounts of collagen to non-collagenous protein synthesized was comparable to that of controls. When the exposed (0.8 ppm O 3 /7 days) animals were placed in filtered ambient air, PH activity returned to normal in 13 days whereas Hyp content remained elevated for up to 28 days. These results suggest that environmental ozone exposure could be a contributing factor in pulmonary disorders involving lung collagen synthesis." @default.
- W2039044218 created "2016-06-24" @default.
- W2039044218 creator A5017260886 @default.
- W2039044218 creator A5045275569 @default.
- W2039044218 creator A5050351684 @default.
- W2039044218 creator A5066240613 @default.
- W2039044218 date "1976-05-01" @default.
- W2039044218 modified "2023-09-27" @default.
- W2039044218 title "Hydroxyproline contents and prolyl hydroxylase activities in lungs of rats exposed to low levels of ozone" @default.
- W2039044218 cites W1537622507 @default.
- W2039044218 cites W1602423734 @default.
- W2039044218 cites W1982667179 @default.
- W2039044218 cites W1991129886 @default.
- W2039044218 cites W1997861316 @default.
- W2039044218 cites W2012093042 @default.
- W2039044218 cites W2020471728 @default.
- W2039044218 cites W2034462747 @default.
- W2039044218 cites W2034595537 @default.
- W2039044218 cites W2038563109 @default.
- W2039044218 cites W2055830465 @default.
- W2039044218 cites W2063999496 @default.
- W2039044218 cites W2066131619 @default.
- W2039044218 cites W2081294436 @default.
- W2039044218 cites W2081446877 @default.
- W2039044218 cites W2155647695 @default.
- W2039044218 cites W2413419379 @default.
- W2039044218 cites W2497050378 @default.
- W2039044218 cites W4249379842 @default.
- W2039044218 doi "https://doi.org/10.1016/0024-3205(76)90406-9" @default.
- W2039044218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/178970" @default.
- W2039044218 hasPublicationYear "1976" @default.
- W2039044218 type Work @default.
- W2039044218 sameAs 2039044218 @default.
- W2039044218 citedByCount "27" @default.
- W2039044218 crossrefType "journal-article" @default.
- W2039044218 hasAuthorship W2039044218A5017260886 @default.
- W2039044218 hasAuthorship W2039044218A5045275569 @default.
- W2039044218 hasAuthorship W2039044218A5050351684 @default.
- W2039044218 hasAuthorship W2039044218A5066240613 @default.
- W2039044218 hasConcept C126322002 @default.
- W2039044218 hasConcept C134018914 @default.
- W2039044218 hasConcept C178790620 @default.
- W2039044218 hasConcept C181199279 @default.
- W2039044218 hasConcept C185592680 @default.
- W2039044218 hasConcept C2777714996 @default.
- W2039044218 hasConcept C2779797417 @default.
- W2039044218 hasConcept C2779815552 @default.
- W2039044218 hasConcept C28212737 @default.
- W2039044218 hasConcept C508106653 @default.
- W2039044218 hasConcept C515207424 @default.
- W2039044218 hasConcept C553450214 @default.
- W2039044218 hasConcept C55493867 @default.
- W2039044218 hasConcept C71924100 @default.
- W2039044218 hasConcept C86803240 @default.
- W2039044218 hasConceptScore W2039044218C126322002 @default.
- W2039044218 hasConceptScore W2039044218C134018914 @default.
- W2039044218 hasConceptScore W2039044218C178790620 @default.
- W2039044218 hasConceptScore W2039044218C181199279 @default.
- W2039044218 hasConceptScore W2039044218C185592680 @default.
- W2039044218 hasConceptScore W2039044218C2777714996 @default.
- W2039044218 hasConceptScore W2039044218C2779797417 @default.
- W2039044218 hasConceptScore W2039044218C2779815552 @default.
- W2039044218 hasConceptScore W2039044218C28212737 @default.
- W2039044218 hasConceptScore W2039044218C508106653 @default.
- W2039044218 hasConceptScore W2039044218C515207424 @default.
- W2039044218 hasConceptScore W2039044218C553450214 @default.
- W2039044218 hasConceptScore W2039044218C55493867 @default.
- W2039044218 hasConceptScore W2039044218C71924100 @default.
- W2039044218 hasConceptScore W2039044218C86803240 @default.
- W2039044218 hasLocation W20390442181 @default.
- W2039044218 hasLocation W20390442182 @default.
- W2039044218 hasOpenAccess W2039044218 @default.
- W2039044218 hasPrimaryLocation W20390442181 @default.
- W2039044218 hasRelatedWork W1538697650 @default.
- W2039044218 hasRelatedWork W1588590018 @default.
- W2039044218 hasRelatedWork W1936518725 @default.
- W2039044218 hasRelatedWork W1965547086 @default.
- W2039044218 hasRelatedWork W1970671830 @default.
- W2039044218 hasRelatedWork W1975905428 @default.
- W2039044218 hasRelatedWork W1978239175 @default.
- W2039044218 hasRelatedWork W2041121024 @default.
- W2039044218 hasRelatedWork W2092564717 @default.
- W2039044218 hasRelatedWork W845391634 @default.
- W2039044218 isParatext "false" @default.
- W2039044218 isRetracted "false" @default.
- W2039044218 magId "2039044218" @default.
- W2039044218 workType "article" @default.