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• W2039085652 abstract "Eleven new triterpene saponins, ilexpublesnins C–M (<b>1</b>–<b>11</b>), along with ten known analogues were isolated from the roots of <i>Ilex pubescens</i>. Their structures were elucidated on the basis of extensive spectroscopic analysis, including 1D and 2D NMR experiments. Compounds <b>1, 2, 10</b>, and <b>11</b> contain a 24-aldehyde, which is rare for triterpene saponins from <i>Ilex</i>. These compounds were evaluated <i>in vitro</i> for their cytotoxic effects on human cancer cell lines HepG2, HLE, BEL7402, BEL7403, BEL7405, MCF-7, and HeLa. Among them, only compounds <b>6</b> and <b>19</b> showed cytotoxicity against the MCF-7 cell line [inhibition (%): 33.14 and 34.03, respectively]." @default.
• W2039085652 created "2016-06-24" @default.
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• W2039085652 date "2012-11-16" @default.
• W2039085652 modified "2023-10-16" @default.
• W2039085652 title "Ilexpublesnins C–M, Eleven New Triterpene Saponins from the Roots of Ilex pubescens" @default.
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• W2039085652 doi "https://doi.org/10.1055/s-0032-1327927" @default.
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