FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039098506> ?p ?o ?g. }

• W2039098506 abstract "Abstract Eighteen studies were performed in 5 grossly obese adolescents in order to determine whether or not epinephrine and/or Propranolol are capable of decreasing the hyperinsulinemia characteristic of obese subjects and to study the metabolic response during the administration of these drugs. When epinephrine (6 μg./min.) was infused during a protein-glucose meal, there was a 50 per cent (or greater) decrease in the release of immunoreactive insulin as compared with the response to protein-glucose alone. However, the basal level of immunoreactive insulin was unchanged. There were also a marked hyperglycemia as well as a concomitant rise in the plasma free fatty acids. Plasma level of immunoreactive human growth hormone were undetectable. Epinephrine (10 μg./min.) in combination with Propranolol (80 μg./min.) resulted in a marked decrease in both the basal level and the subsequent release of immunoreactive insulin. Hyperglycemia was present and the plasma free fatty acids showed a precipitous fall. One patient had a brisk immunoreactive growth hormone response of 7 mμg./ml. after cessation of the infusion. When epinephrine (2 μg./min.) was simultaneously infused with Propranolol (80 μg./min.) only a slight decrease in the basal level of immunoreactive insulin was observed. The inhibition of the subsequent insulin release was mild and transitory. Again hyperglycemia occurred and the plasma levels of immunoreactive growth hormone were almost undetectable. Propranolol alone (80 μg./min.) did not affect the basal level or the subsequent release of immunoreactive insulin. One subject had a peak plasma immunoreactive growth hormone value of 5.9 mμg./ml. shortly after the infusion began. It is concluded that Propranolol and epinephrine in specific dose combinations have a synergistic action on the inhibition of insulin release in obese adolescents." @default.
• W2039098506 created "2016-06-24" @default.
• W2039098506 creator A5045901916 @default.
• W2039098506 creator A5090634917 @default.
• W2039098506 date "1969-06-01" @default.
• W2039098506 modified "2023-09-27" @default.
• W2039098506 title "Metabolic response to simultaneous infusion of epinephrine and Propranolol in obese adolescents" @default.
• W2039098506 cites W1539810639 @default.
• W2039098506 cites W1773683135 @default.
• W2039098506 cites W1944989204 @default.
• W2039098506 cites W1966121483 @default.
• W2039098506 cites W1968294974 @default.
• W2039098506 cites W1973758579 @default.
• W2039098506 cites W1975070600 @default.
• W2039098506 cites W1978140190 @default.
• W2039098506 cites W2012664819 @default.
• W2039098506 cites W2056386148 @default.
• W2039098506 cites W2063562555 @default.
• W2039098506 cites W2078073869 @default.
• W2039098506 cites W2089837994 @default.
• W2039098506 cites W2152358765 @default.
• W2039098506 cites W2204125127 @default.
• W2039098506 cites W2281938476 @default.
• W2039098506 cites W2319180293 @default.
• W2039098506 cites W3023173633 @default.
• W2039098506 doi "https://doi.org/10.1016/0026-0495(69)90143-7" @default.
• W2039098506 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4891083" @default.
• W2039098506 hasPublicationYear "1969" @default.
• W2039098506 type Work @default.
• W2039098506 sameAs 2039098506 @default.
• W2039098506 citedByCount "7" @default.
• W2039098506 crossrefType "journal-article" @default.
• W2039098506 hasAuthorship W2039098506A5045901916 @default.
• W2039098506 hasAuthorship W2039098506A5090634917 @default.
• W2039098506 hasConcept C126322002 @default.
• W2039098506 hasConcept C134018914 @default.
• W2039098506 hasConcept C185592680 @default.
• W2039098506 hasConcept C2775859304 @default.
• W2039098506 hasConcept C2777391703 @default.
• W2039098506 hasConcept C2778024521 @default.
• W2039098506 hasConcept C2778151854 @default.
• W2039098506 hasConcept C2779306644 @default.
• W2039098506 hasConcept C2780988686 @default.
• W2039098506 hasConcept C71315377 @default.
• W2039098506 hasConcept C71924100 @default.
• W2039098506 hasConceptScore W2039098506C126322002 @default.
• W2039098506 hasConceptScore W2039098506C134018914 @default.
• W2039098506 hasConceptScore W2039098506C185592680 @default.
• W2039098506 hasConceptScore W2039098506C2775859304 @default.
• W2039098506 hasConceptScore W2039098506C2777391703 @default.
• W2039098506 hasConceptScore W2039098506C2778024521 @default.
• W2039098506 hasConceptScore W2039098506C2778151854 @default.
• W2039098506 hasConceptScore W2039098506C2779306644 @default.
• W2039098506 hasConceptScore W2039098506C2780988686 @default.
• W2039098506 hasConceptScore W2039098506C71315377 @default.
• W2039098506 hasConceptScore W2039098506C71924100 @default.
• W2039098506 hasLocation W20390985061 @default.
• W2039098506 hasLocation W20390985062 @default.
• W2039098506 hasOpenAccess W2039098506 @default.
• W2039098506 hasPrimaryLocation W20390985061 @default.
• W2039098506 hasRelatedWork W1839672624 @default.
• W2039098506 hasRelatedWork W2021027749 @default.
• W2039098506 hasRelatedWork W2022212333 @default.
• W2039098506 hasRelatedWork W2039098506 @default.
• W2039098506 hasRelatedWork W2053519879 @default.
• W2039098506 hasRelatedWork W2096017546 @default.
• W2039098506 hasRelatedWork W2110053809 @default.
• W2039098506 hasRelatedWork W2171992221 @default.
• W2039098506 hasRelatedWork W2292878995 @default.
• W2039098506 hasRelatedWork W2417897234 @default.
• W2039098506 isParatext "false" @default.
• W2039098506 isRetracted "false" @default.
• W2039098506 magId "2039098506" @default.
• W2039098506 workType "article" @default.