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- W2039104311 abstract "Summary Highly sensitive individuals had the least grey matter density in the bilateral precuneus, posterior cingulate cortex, posterior parietal cortex, and left primary somatosensory cortex. Pain is a highly personal experience that varies substantially among individuals. In search of an anatomical correlate of pain sensitivity, we used voxel-based morphometry to investigate the relationship between grey matter density across the whole brain and interindividual differences in pain sensitivity in 116 healthy volunteers (62 women, 54 men). Structural magnetic resonance imaging (MRI) and psychophysical data from 10 previous functional MRI studies were used. Age, sex, unpleasantness ratings, scanner sequence, and sensory testing location were added to the model as covariates. Regression analysis of grey matter density across the whole brain and thermal pain intensity ratings at 49 °C revealed a significant inverse relationship between pain sensitivity and grey matter density in bilateral regions of the posterior cingulate cortex, precuneus, intraparietal sulcus, and inferior parietal lobule. Unilateral regions of the left primary somatosensory cortex also exhibited this inverse relationship. No regions showed a positive relationship to pain sensitivity. These structural variations occurred in areas associated with the default mode network, attentional direction and shifting, as well as somatosensory processing. These findings underscore the potential importance of processes related to default mode thought and attention in shaping individual differences in pain sensitivity and indicate that pain sensitivity can potentially be predicted on the basis of brain structure." @default.
- W2039104311 created "2016-06-24" @default.
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- W2039104311 date "2014-03-01" @default.
- W2039104311 modified "2023-10-14" @default.
- W2039104311 title "Pain sensitivity is inversely related to regional grey matter density in the brain" @default.
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- W2039104311 cites W1972843439 @default.
- W2039104311 cites W1977248443 @default.
- W2039104311 cites W1978661701 @default.
- W2039104311 cites W1983368104 @default.
- W2039104311 cites W1984632233 @default.
- W2039104311 cites W1985591790 @default.
- W2039104311 cites W1987346764 @default.
- W2039104311 cites W1994143652 @default.
- W2039104311 cites W1999557137 @default.
- W2039104311 cites W2006096283 @default.
- W2039104311 cites W2013935441 @default.
- W2039104311 cites W2017404787 @default.
- W2039104311 cites W2022549154 @default.
- W2039104311 cites W2023347974 @default.
- W2039104311 cites W2027661851 @default.
- W2039104311 cites W2044882439 @default.
- W2039104311 cites W2046557060 @default.
- W2039104311 cites W2053443700 @default.
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- W2039104311 cites W2085846591 @default.
- W2039104311 cites W2090202944 @default.
- W2039104311 cites W2092898810 @default.
- W2039104311 cites W2095901107 @default.
- W2039104311 cites W2107754415 @default.
- W2039104311 cites W2109173536 @default.
- W2039104311 cites W2110004800 @default.
- W2039104311 cites W2110543343 @default.
- W2039104311 cites W2112313930 @default.
- W2039104311 cites W2112900258 @default.
- W2039104311 cites W2114254750 @default.
- W2039104311 cites W2117207767 @default.
- W2039104311 cites W2118252411 @default.
- W2039104311 cites W2118421222 @default.
- W2039104311 cites W2119792333 @default.
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- W2039104311 cites W2136573752 @default.
- W2039104311 cites W2139898757 @default.
- W2039104311 cites W2145677511 @default.
- W2039104311 cites W2146784485 @default.
- W2039104311 cites W2148726987 @default.
- W2039104311 cites W2151552027 @default.
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- W2039104311 doi "https://doi.org/10.1016/j.pain.2013.12.004" @default.
- W2039104311 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3944887" @default.
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- W2039104311 hasPublicationYear "2014" @default.
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