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- W2039114562 abstract "Signal loss in gradient-echo echo planar imaging (GE-EPI) due to susceptibility-induced magnetic field inhomogeneity makes it difficult to assess the blood oxygenation level-dependent (BOLD) effect in fMRI investigations. The z-shim method that applies an additional gradient moment is one of the more popular methods of compensating for GE-EPI signal loss. However, this method requires a calibration sweep scan and post-processing to identify the optimal z-shim gradients, which slows down fMRI experiments. This study attempts to decrease the calibration time by introducing a real-time feedback framework. Creating a feedback loop between the image processing and the GE-EPI pulse sequence converts the calibration of z-shim gradients to an optimization problem, which can be accelerated by local search methods. This study proposes an interleaved scan that allows the simultaneous optimization of two z-shim gradient moments and allocates sufficient processing time for networking and computation. The z-shim compensated images obtained by the proposed real-time method are comparable to those created by the sweep method. The optimization procedure for obtaining negative and positive gradient moments generally requires about twenty GE-EPI repetitions. In conclusion, the proposed z-shim method includes an automated real-time framework to achieve a significant reduction in susceptibility-induced signal loss in GE-EPI with a minimal increase in calibration time. The proposed procedure is fully automatic and compatible with conventional GE-EPI and can thus serve as a pre-adjustment module in EPI-based fMRI researches." @default.
- W2039114562 created "2016-06-24" @default.
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- W2039114562 date "2011-04-01" @default.
- W2039114562 modified "2023-10-14" @default.
- W2039114562 title "Real-time feedback optimization of z-shim gradient for automatic compensation of susceptibility-induced signal loss in EPI" @default.
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- W2039114562 doi "https://doi.org/10.1016/j.neuroimage.2011.01.045" @default.
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