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- W2039115887 abstract "Abstract DNA glycosylases acting upon uracil- or 3-methyl-adenine-containing DNA have been detected in the sonic extracts of the nematode, Caenorhabditis elegans. 4 types of the asynchronously-growing worms, embryos obtained from gravid hermaphrodites, aseptically-hatched larvae, or dauer larvae. Uracil-DNA glcosylase activity was found in all 4 types of the extracts, and the activity was highest in the embryonic extract. In contrast, 3-methyladenine-DNA glycosylase activity was undetectable in the embryonic extract, while an equal level of activity was found in the other 3 types of the extracts. The results substantiate the ubiquity of base-excision repair in various organisms, and suggest that some of the repair functions may be developmentally regulated in multicellular animals." @default.
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- W2039115887 date "1986-03-01" @default.
- W2039115887 modified "2023-09-25" @default.
- W2039115887 title "DNA glycosylase activities in the nematode, Caenorhabditis elegans" @default.
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- W2039115887 doi "https://doi.org/10.1016/0167-8817(86)90065-9" @default.
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