FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039162021> ?p ?o ?g. }

• W2039162021 endingPage "308" @default.
• W2039162021 startingPage "301" @default.
• W2039162021 abstract "Glucocorticoid receptors (GR) are ubiquitous molecules and are present also in the hippocampus and in several other nervous and immune tissues. Peripheral blood mononuclear cells (PBMCs) are a good model for studies of GR in humans. Glucocorticoids are important for maintaining cellular and humoral homeostasis and are key mediators of neuroendocrine-immune regulatory interactions. The increase of cortisol is immunosuppressive and reduces GR concentration both in nervous and immune systems. Variation of glucocorticoids in healthy aged subjects and athletes has been shown. Prompted by these results, we have investigated in man a possible relationship between GR binding capacity in the PBMCs and age, in relation also to plasma testosterone and cortisol. The same parameters have been examined in a group of soccer players for comparison with the sedentary group. GR binding capacity was higher in younger subjects than in older ones, and lower in the group of athletes than in the younger and older sedentary subjects. In the sedentary group a negative correlation was present between GR binding capacity and age. Plasma cortisol was higher and testosterone lower in the athletes; they were negatively correlated in athletes and positively correlated in the sedentary subjects. The results for athletes agree with their lower anabolic/catabolic balance. The mechanism of reduced GR levels in relation to age and sport activity could involve a loss or an involution of receptor synthesis. However other possibilities, such as altered distribution of lymphocyte subpopulations with different receptor concentrations and with different cytokine production, cannot be excluded. Several neuroendocrine-immune interactions could be responsible for reduced GR levels with age and sport activity in man." @default.
• W2039162021 created "2016-06-24" @default.
• W2039162021 creator A5018465034 @default.
• W2039162021 creator A5061049828 @default.
• W2039162021 creator A5076351048 @default.
• W2039162021 creator A5085291201 @default.
• W2039162021 date "1997-06-01" @default.
• W2039162021 modified "2023-10-17" @default.
• W2039162021 title "GLUCOCORTICOID RECEPTORS IN HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS IN RELATION TO AGE AND TO SPORT ACTIVITY" @default.
• W2039162021 cites W1602332987 @default.
• W2039162021 cites W1607307677 @default.
• W2039162021 cites W1926627063 @default.
• W2039162021 cites W1938298510 @default.
• W2039162021 cites W1966513493 @default.
• W2039162021 cites W1968024443 @default.
• W2039162021 cites W1970628050 @default.
• W2039162021 cites W1977143695 @default.
• W2039162021 cites W1983649348 @default.
• W2039162021 cites W1987074109 @default.
• W2039162021 cites W1994594346 @default.
• W2039162021 cites W1998086688 @default.
• W2039162021 cites W2000899110 @default.
• W2039162021 cites W2015603101 @default.
• W2039162021 cites W2016223886 @default.
• W2039162021 cites W2020167840 @default.
• W2039162021 cites W2035072797 @default.
• W2039162021 cites W2041064840 @default.
• W2039162021 cites W2043324873 @default.
• W2039162021 cites W2050815672 @default.
• W2039162021 cites W2055516348 @default.
• W2039162021 cites W2059051245 @default.
• W2039162021 cites W2059846999 @default.
• W2039162021 cites W2065948070 @default.
• W2039162021 cites W2065968630 @default.
• W2039162021 cites W2068392981 @default.
• W2039162021 cites W2071393344 @default.
• W2039162021 cites W2078904015 @default.
• W2039162021 cites W2079007749 @default.
• W2039162021 cites W2080947349 @default.
• W2039162021 cites W2081300696 @default.
• W2039162021 cites W2089131135 @default.
• W2039162021 cites W2113962949 @default.
• W2039162021 cites W2148496989 @default.
• W2039162021 cites W4252612701 @default.
• W2039162021 cites W4255409714 @default.
• W2039162021 doi "https://doi.org/10.1016/s0024-3205(97)00386-x" @default.
• W2039162021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9217290" @default.
• W2039162021 hasPublicationYear "1997" @default.
• W2039162021 type Work @default.
• W2039162021 sameAs 2039162021 @default.
• W2039162021 citedByCount "48" @default.
• W2039162021 countsByYear W20391620212013 @default.
• W2039162021 countsByYear W20391620212014 @default.
• W2039162021 countsByYear W20391620212015 @default.
• W2039162021 countsByYear W20391620212016 @default.
• W2039162021 countsByYear W20391620212018 @default.
• W2039162021 countsByYear W20391620212019 @default.
• W2039162021 countsByYear W20391620212021 @default.
• W2039162021 crossrefType "journal-article" @default.
• W2039162021 hasAuthorship W2039162021A5018465034 @default.
• W2039162021 hasAuthorship W2039162021A5061049828 @default.
• W2039162021 hasAuthorship W2039162021A5076351048 @default.
• W2039162021 hasAuthorship W2039162021A5085291201 @default.
• W2039162021 hasConcept C126322002 @default.
• W2039162021 hasConcept C134018914 @default.
• W2039162021 hasConcept C137061746 @default.
• W2039162021 hasConcept C170493617 @default.
• W2039162021 hasConcept C202751555 @default.
• W2039162021 hasConcept C203014093 @default.
• W2039162021 hasConcept C2776090121 @default.
• W2039162021 hasConcept C2777314012 @default.
• W2039162021 hasConcept C2777761686 @default.
• W2039162021 hasConcept C2778690821 @default.
• W2039162021 hasConcept C2779279991 @default.
• W2039162021 hasConcept C2780841215 @default.
• W2039162021 hasConcept C55493867 @default.
• W2039162021 hasConcept C59493245 @default.
• W2039162021 hasConcept C63645605 @default.
• W2039162021 hasConcept C71924100 @default.
• W2039162021 hasConcept C86803240 @default.
• W2039162021 hasConcept C8891405 @default.
• W2039162021 hasConceptScore W2039162021C126322002 @default.
• W2039162021 hasConceptScore W2039162021C134018914 @default.
• W2039162021 hasConceptScore W2039162021C137061746 @default.
• W2039162021 hasConceptScore W2039162021C170493617 @default.
• W2039162021 hasConceptScore W2039162021C202751555 @default.
• W2039162021 hasConceptScore W2039162021C203014093 @default.
• W2039162021 hasConceptScore W2039162021C2776090121 @default.
• W2039162021 hasConceptScore W2039162021C2777314012 @default.
• W2039162021 hasConceptScore W2039162021C2777761686 @default.
• W2039162021 hasConceptScore W2039162021C2778690821 @default.
• W2039162021 hasConceptScore W2039162021C2779279991 @default.
• W2039162021 hasConceptScore W2039162021C2780841215 @default.
• W2039162021 hasConceptScore W2039162021C55493867 @default.
• W2039162021 hasConceptScore W2039162021C59493245 @default.
• W2039162021 hasConceptScore W2039162021C63645605 @default.
• W2039162021 hasConceptScore W2039162021C71924100 @default.
• W2039162021 hasConceptScore W2039162021C86803240 @default.

• next