FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039171925> ?p ?o ?g. }

• W2039171925 endingPage "290" @default.
• W2039171925 startingPage "284" @default.
• W2039171925 abstract "In the nanotechnology field, the concept of using biomolecules as an elementary structure to develop self-assembled entities has received considerable attention. Particularly, the ability of amphiphilic molecules like lipids to self-organize into bilayers can be exploited to provide biomimetic membrane models. Langmuir–Blodgett (LB) technology, based on the transfer of an interfacial film onto a solid support, offers the possibility to prepare lipid bilayers suitable for biomolecule immobilization and achievement of nanoscale-organized sensing layers, tailored for the design of miniaturized biosensors. With the aim of immobilizing enzymes in a defined orientation at the surface of LB bilayers, an original strategy has been previously developed in our group. This approach combines two techniques based on molecular self-assembly properties: liposome fusion at an air/buffer interface and Langmuir–Blodgett technology. It allows the functional insertion of a non-inhibitory antibody in lipid bilayers, further used to anchor a soluble enzyme at the surface of the lipid membrane. When associated with an electrochemiluminescent (ECL) sensor, this molecular assembly allows the design of a biomimetic sensor able to closely integrate the recognition and transduction events. However, sensor's performance not only depends on bioactive sensing layer properties, but also on the additional introduction of luminol in the reaction medium which delays ECL reaction. This work explores the potentiality of two neosynthesized amphiphilic luminol derivatives to form a lipid bilayer serving as a matrix used for both antibody insertion and ECL detection in order to develop a new sensing layer allowing a reagentless detection. As a model, choline oxidase activity has been detected. After enzyme immobilization at the surface of the luminol derivative LB bilayer by the way of specific recognition of a non-inhibitory antibody, in situ catalytic generation of hydrogen peroxide is able to trigger ECL reaction in the sensing layer interfaced with an optoelectronic device leading to a reagentless detection of choline oxidase activity." @default.
• W2039171925 created "2016-06-24" @default.
• W2039171925 creator A5004556206 @default.
• W2039171925 creator A5015180133 @default.
• W2039171925 creator A5035765631 @default.
• W2039171925 creator A5055417982 @default.
• W2039171925 creator A5066710763 @default.
• W2039171925 date "2010-02-01" @default.
• W2039171925 modified "2023-10-09" @default.
• W2039171925 title "A chemiluminescent Langmuir–Blodgett membrane as the sensing layer for the reagentless monitoring of an immobilized enzyme activity" @default.
• W2039171925 cites W1966389983 @default.
• W2039171925 cites W1970446260 @default.
• W2039171925 cites W1970965952 @default.
• W2039171925 cites W1971245608 @default.
• W2039171925 cites W1972454517 @default.
• W2039171925 cites W1993854987 @default.
• W2039171925 cites W1994700212 @default.
• W2039171925 cites W199706411 @default.
• W2039171925 cites W1998509613 @default.
• W2039171925 cites W2000130623 @default.
• W2039171925 cites W2002912499 @default.
• W2039171925 cites W2005889717 @default.
• W2039171925 cites W2007200128 @default.
• W2039171925 cites W2015738484 @default.
• W2039171925 cites W2018483275 @default.
• W2039171925 cites W2020898688 @default.
• W2039171925 cites W2021604540 @default.
• W2039171925 cites W2024433819 @default.
• W2039171925 cites W2025780764 @default.
• W2039171925 cites W2033525666 @default.
• W2039171925 cites W2033561379 @default.
• W2039171925 cites W2037741618 @default.
• W2039171925 cites W2047238354 @default.
• W2039171925 cites W2049294377 @default.
• W2039171925 cites W2052693297 @default.
• W2039171925 cites W2052734172 @default.
• W2039171925 cites W2059346211 @default.
• W2039171925 cites W2064715790 @default.
• W2039171925 cites W2072135518 @default.
• W2039171925 cites W2075595419 @default.
• W2039171925 cites W2083339045 @default.
• W2039171925 cites W2139371102 @default.
• W2039171925 cites W4297899017 @default.
• W2039171925 doi "https://doi.org/10.1016/j.colsurfa.2009.07.034" @default.
• W2039171925 hasPublicationYear "2010" @default.
• W2039171925 type Work @default.
• W2039171925 sameAs 2039171925 @default.
• W2039171925 citedByCount "24" @default.
• W2039171925 countsByYear W20391719252012 @default.
• W2039171925 countsByYear W20391719252013 @default.
• W2039171925 countsByYear W20391719252014 @default.
• W2039171925 countsByYear W20391719252015 @default.
• W2039171925 countsByYear W20391719252016 @default.
• W2039171925 countsByYear W20391719252017 @default.
• W2039171925 countsByYear W20391719252018 @default.
• W2039171925 countsByYear W20391719252019 @default.
• W2039171925 countsByYear W20391719252021 @default.
• W2039171925 countsByYear W20391719252022 @default.
• W2039171925 crossrefType "journal-article" @default.
• W2039171925 hasAuthorship W2039171925A5004556206 @default.
• W2039171925 hasAuthorship W2039171925A5015180133 @default.
• W2039171925 hasAuthorship W2039171925A5035765631 @default.
• W2039171925 hasAuthorship W2039171925A5055417982 @default.
• W2039171925 hasAuthorship W2039171925A5066710763 @default.
• W2039171925 hasConcept C145802702 @default.
• W2039171925 hasConcept C155672457 @default.
• W2039171925 hasConcept C15920480 @default.
• W2039171925 hasConcept C160756335 @default.
• W2039171925 hasConcept C171250308 @default.
• W2039171925 hasConcept C178790620 @default.
• W2039171925 hasConcept C180235531 @default.
• W2039171925 hasConcept C185592680 @default.
• W2039171925 hasConcept C190818770 @default.
• W2039171925 hasConcept C192157962 @default.
• W2039171925 hasConcept C192562407 @default.
• W2039171925 hasConcept C39944091 @default.
• W2039171925 hasConcept C41625074 @default.
• W2039171925 hasConcept C49853544 @default.
• W2039171925 hasConcept C521977710 @default.
• W2039171925 hasConcept C55493867 @default.
• W2039171925 hasConcept C67407626 @default.
• W2039171925 hasConcept C7070889 @default.
• W2039171925 hasConceptScore W2039171925C145802702 @default.
• W2039171925 hasConceptScore W2039171925C155672457 @default.
• W2039171925 hasConceptScore W2039171925C15920480 @default.
• W2039171925 hasConceptScore W2039171925C160756335 @default.
• W2039171925 hasConceptScore W2039171925C171250308 @default.
• W2039171925 hasConceptScore W2039171925C178790620 @default.
• W2039171925 hasConceptScore W2039171925C180235531 @default.
• W2039171925 hasConceptScore W2039171925C185592680 @default.
• W2039171925 hasConceptScore W2039171925C190818770 @default.
• W2039171925 hasConceptScore W2039171925C192157962 @default.
• W2039171925 hasConceptScore W2039171925C192562407 @default.
• W2039171925 hasConceptScore W2039171925C39944091 @default.
• W2039171925 hasConceptScore W2039171925C41625074 @default.
• W2039171925 hasConceptScore W2039171925C49853544 @default.
• W2039171925 hasConceptScore W2039171925C521977710 @default.
• W2039171925 hasConceptScore W2039171925C55493867 @default.

• next