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• W2039172022 abstract "The chicken MHC-B locus affects the response to several strains of Rous sarcoma virus (RSV). We evaluated the association between haplotypes of the MHC-B locus and responses to the J strain of RSV by using an F2 experimental resource family constructed with tumor-regressive (White Leghorn) and tumor-progressive (Rhode Island Red) chickens. The MHC-B haplotypes were determined by genotyping of the microsatellite marker LEI0258 and MHC-B locus class I α chain 2 (BF2). Two haplotypes in the resource family, one associated with tumor regression and one with progression, were defined by these 2 markers. To discriminate more precisely the regressive haplotype in this family, we further developed 35 SNP markers at the MHC-B locus. Information on the haplotypes revealed here should be useful for identifying chickens with regression and progression phenotypes of J-strain RSV-induced tumors." @default.
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• W2039172022 date "2010-04-01" @default.
• W2039172022 modified "2023-10-18" @default.
• W2039172022 title "Genotypes of chicken major histocompatibility complex B locus associated with regression of Rous sarcoma virus J-strain tumors" @default.
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• W2039172022 doi "https://doi.org/10.3382/ps.2009-00513" @default.
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