Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039231803> ?p ?o ?g. }
- W2039231803 endingPage "736" @default.
- W2039231803 startingPage "727" @default.
- W2039231803 abstract "A molecular beacon (MB) array was designed based on unique regions of the 16S rRNA of the bacterium Francisella tularensis. Nucleic acid molecular beacons undergo a spontaneous fluorogenic conformational change when they hybridize to specific complementary targets. The array was printed on aldehyde glass or hydrogel slides and evaluated for functioning in presence of complementary oligonucleotide sequences, single-nucleotide mismatch sequences and multiple nucleotide mismatch sequences. Discriminating true target from mismatched targets was found to be dependent on type, number, and location of mismatches within the beacon (i.e. located in the stem or loop regions). Optimal conditions for molecular beacon deposition, and target hybridization were determined for oligonucleotide target mismatch discrimination. The beacon array was stable upon recharging by exposure to an alkaline solution, and repeatedly used. In addition, performance of the beacon array biosensor was compared with molecular beacons in homogeneous solution." @default.
- W2039231803 created "2016-06-24" @default.
- W2039231803 creator A5004007392 @default.
- W2039231803 creator A5004302315 @default.
- W2039231803 creator A5006895637 @default.
- W2039231803 creator A5053819144 @default.
- W2039231803 creator A5089206483 @default.
- W2039231803 date "2004-02-01" @default.
- W2039231803 modified "2023-09-27" @default.
- W2039231803 title "Target discrimination by surface-immobilized molecular beacons designed to detect Francisella tularensis" @default.
- W2039231803 cites W1519185585 @default.
- W2039231803 cites W1583683345 @default.
- W2039231803 cites W1696298601 @default.
- W2039231803 cites W1987069778 @default.
- W2039231803 cites W1991065758 @default.
- W2039231803 cites W1999119486 @default.
- W2039231803 cites W2002479245 @default.
- W2039231803 cites W2004639986 @default.
- W2039231803 cites W2007783248 @default.
- W2039231803 cites W2009818318 @default.
- W2039231803 cites W2011198763 @default.
- W2039231803 cites W2018466980 @default.
- W2039231803 cites W2026710381 @default.
- W2039231803 cites W2048471241 @default.
- W2039231803 cites W2055043387 @default.
- W2039231803 cites W2062253025 @default.
- W2039231803 cites W2062376685 @default.
- W2039231803 cites W2076558135 @default.
- W2039231803 cites W2088337738 @default.
- W2039231803 cites W2093643675 @default.
- W2039231803 cites W2098605152 @default.
- W2039231803 cites W2109056556 @default.
- W2039231803 cites W2116926903 @default.
- W2039231803 cites W2132119662 @default.
- W2039231803 cites W2135995702 @default.
- W2039231803 cites W2141627564 @default.
- W2039231803 cites W2144511136 @default.
- W2039231803 cites W2145704810 @default.
- W2039231803 cites W2155445817 @default.
- W2039231803 cites W2170277012 @default.
- W2039231803 cites W2171409050 @default.
- W2039231803 doi "https://doi.org/10.1016/j.bios.2003.08.004" @default.
- W2039231803 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14709391" @default.
- W2039231803 hasPublicationYear "2004" @default.
- W2039231803 type Work @default.
- W2039231803 sameAs 2039231803 @default.
- W2039231803 citedByCount "47" @default.
- W2039231803 countsByYear W20392318032013 @default.
- W2039231803 countsByYear W20392318032014 @default.
- W2039231803 countsByYear W20392318032015 @default.
- W2039231803 countsByYear W20392318032017 @default.
- W2039231803 countsByYear W20392318032019 @default.
- W2039231803 countsByYear W20392318032021 @default.
- W2039231803 crossrefType "journal-article" @default.
- W2039231803 hasAuthorship W2039231803A5004007392 @default.
- W2039231803 hasAuthorship W2039231803A5004302315 @default.
- W2039231803 hasAuthorship W2039231803A5006895637 @default.
- W2039231803 hasAuthorship W2039231803A5053819144 @default.
- W2039231803 hasAuthorship W2039231803A5089206483 @default.
- W2039231803 hasConcept C102168758 @default.
- W2039231803 hasConcept C104317684 @default.
- W2039231803 hasConcept C111824103 @default.
- W2039231803 hasConcept C119203544 @default.
- W2039231803 hasConcept C129312508 @default.
- W2039231803 hasConcept C145169222 @default.
- W2039231803 hasConcept C153911025 @default.
- W2039231803 hasConcept C160756335 @default.
- W2039231803 hasConcept C185592680 @default.
- W2039231803 hasConcept C24107716 @default.
- W2039231803 hasConcept C2780467176 @default.
- W2039231803 hasConcept C41008148 @default.
- W2039231803 hasConcept C54355233 @default.
- W2039231803 hasConcept C55493867 @default.
- W2039231803 hasConcept C60987743 @default.
- W2039231803 hasConcept C70721500 @default.
- W2039231803 hasConcept C79403827 @default.
- W2039231803 hasConcept C86803240 @default.
- W2039231803 hasConceptScore W2039231803C102168758 @default.
- W2039231803 hasConceptScore W2039231803C104317684 @default.
- W2039231803 hasConceptScore W2039231803C111824103 @default.
- W2039231803 hasConceptScore W2039231803C119203544 @default.
- W2039231803 hasConceptScore W2039231803C129312508 @default.
- W2039231803 hasConceptScore W2039231803C145169222 @default.
- W2039231803 hasConceptScore W2039231803C153911025 @default.
- W2039231803 hasConceptScore W2039231803C160756335 @default.
- W2039231803 hasConceptScore W2039231803C185592680 @default.
- W2039231803 hasConceptScore W2039231803C24107716 @default.
- W2039231803 hasConceptScore W2039231803C2780467176 @default.
- W2039231803 hasConceptScore W2039231803C41008148 @default.
- W2039231803 hasConceptScore W2039231803C54355233 @default.
- W2039231803 hasConceptScore W2039231803C55493867 @default.
- W2039231803 hasConceptScore W2039231803C60987743 @default.
- W2039231803 hasConceptScore W2039231803C70721500 @default.
- W2039231803 hasConceptScore W2039231803C79403827 @default.
- W2039231803 hasConceptScore W2039231803C86803240 @default.
- W2039231803 hasIssue "7" @default.
- W2039231803 hasLocation W20392318031 @default.
- W2039231803 hasLocation W20392318032 @default.