FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039232242> ?p ?o ?g. }

• W2039232242 endingPage "387" @default.
• W2039232242 startingPage "382" @default.
• W2039232242 abstract "This study was done to determine the comparative elimination kinetics of furosemide from chinchilla perilymph and serum, and to correlate perilymph concentration with changes in endocochlear potential. The elimination kinetics of furosemide (FU) were determined in sera and perilymph obtained from chinchillas injected with 100 mg/kg i.v. of FU. Concentrations of FU exhibited a linear decay pattern in serum and perilymph over the initial 60 minutes. The rate of decline of furosemide levels in perilymph was about four times slower than the rate of fall in serum. Chronic treatment (25 mg/kg i.p. every 12 hours) did not appear to influence the level of drug at 60 minutes after a dose of FU (100 mg/kg IV). Chinchillas were also studied following doses of FU ranging from 25–200 mg/kg i.v. to see the effect on endocochlear potential (EP). A positive correlation was found between FU dosage, the maximum millivolt reduction of EP and the time to initiation of recovery of EP. The perilymph concentration of furosemide when the EP began to recover was 5 μg/ml (1.5°10−5 M). Knowledge of furosemide kinetics may ultimately be applied to prevent ototoxicity in patients." @default.
• W2039232242 created "2016-06-24" @default.
• W2039232242 creator A5033649662 @default.
• W2039232242 creator A5034111721 @default.
• W2039232242 creator A5037196389 @default.
• W2039232242 creator A5052036878 @default.
• W2039232242 creator A5061744858 @default.
• W2039232242 date "1979-01-01" @default.
• W2039232242 modified "2023-09-27" @default.
• W2039232242 title "Elimination Kinetics of Furosemide in Perilymph and Serum of the Chinchilla:<i>Neuropharmacologic Correlates</i>" @default.
• W2039232242 cites W10567027 @default.
• W2039232242 cites W107786363 @default.
• W2039232242 cites W143134428 @default.
• W2039232242 cites W1532206227 @default.
• W2039232242 cites W1535847920 @default.
• W2039232242 cites W1965557755 @default.
• W2039232242 cites W1974296977 @default.
• W2039232242 cites W1994699573 @default.
• W2039232242 cites W2007012689 @default.
• W2039232242 cites W2007350339 @default.
• W2039232242 cites W2013979964 @default.
• W2039232242 cites W2027146452 @default.
• W2039232242 cites W2031579832 @default.
• W2039232242 cites W2050968156 @default.
• W2039232242 cites W2062052466 @default.
• W2039232242 cites W2066537961 @default.
• W2039232242 cites W2096663915 @default.
• W2039232242 cites W2111777003 @default.
• W2039232242 cites W2157426922 @default.
• W2039232242 cites W2318891833 @default.
• W2039232242 cites W2409370544 @default.
• W2039232242 cites W2415617471 @default.
• W2039232242 cites W2416510158 @default.
• W2039232242 cites W2470300408 @default.
• W2039232242 cites W2950608431 @default.
• W2039232242 doi "https://doi.org/10.3109/00016487909137182" @default.
• W2039232242 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/532613" @default.
• W2039232242 hasPublicationYear "1979" @default.
• W2039232242 type Work @default.
• W2039232242 sameAs 2039232242 @default.
• W2039232242 citedByCount "35" @default.
• W2039232242 countsByYear W20392322422012 @default.
• W2039232242 countsByYear W20392322422019 @default.
• W2039232242 countsByYear W20392322422020 @default.
• W2039232242 countsByYear W20392322422022 @default.
• W2039232242 crossrefType "journal-article" @default.
• W2039232242 hasAuthorship W2039232242A5033649662 @default.
• W2039232242 hasAuthorship W2039232242A5034111721 @default.
• W2039232242 hasAuthorship W2039232242A5037196389 @default.
• W2039232242 hasAuthorship W2039232242A5052036878 @default.
• W2039232242 hasAuthorship W2039232242A5061744858 @default.
• W2039232242 hasConcept C105702510 @default.
• W2039232242 hasConcept C121332964 @default.
• W2039232242 hasConcept C126322002 @default.
• W2039232242 hasConcept C134018914 @default.
• W2039232242 hasConcept C148898269 @default.
• W2039232242 hasConcept C185592680 @default.
• W2039232242 hasConcept C2777955127 @default.
• W2039232242 hasConcept C2778317342 @default.
• W2039232242 hasConcept C2778815084 @default.
• W2039232242 hasConcept C2779415040 @default.
• W2039232242 hasConcept C2780130748 @default.
• W2039232242 hasConcept C2780921233 @default.
• W2039232242 hasConcept C62520636 @default.
• W2039232242 hasConcept C71924100 @default.
• W2039232242 hasConcept C98274493 @default.
• W2039232242 hasConceptScore W2039232242C105702510 @default.
• W2039232242 hasConceptScore W2039232242C121332964 @default.
• W2039232242 hasConceptScore W2039232242C126322002 @default.
• W2039232242 hasConceptScore W2039232242C134018914 @default.
• W2039232242 hasConceptScore W2039232242C148898269 @default.
• W2039232242 hasConceptScore W2039232242C185592680 @default.
• W2039232242 hasConceptScore W2039232242C2777955127 @default.
• W2039232242 hasConceptScore W2039232242C2778317342 @default.
• W2039232242 hasConceptScore W2039232242C2778815084 @default.
• W2039232242 hasConceptScore W2039232242C2779415040 @default.
• W2039232242 hasConceptScore W2039232242C2780130748 @default.
• W2039232242 hasConceptScore W2039232242C2780921233 @default.
• W2039232242 hasConceptScore W2039232242C62520636 @default.
• W2039232242 hasConceptScore W2039232242C71924100 @default.
• W2039232242 hasConceptScore W2039232242C98274493 @default.
• W2039232242 hasIssue "1-6" @default.
• W2039232242 hasLocation W20392322421 @default.
• W2039232242 hasLocation W20392322422 @default.
• W2039232242 hasOpenAccess W2039232242 @default.
• W2039232242 hasPrimaryLocation W20392322421 @default.
• W2039232242 hasRelatedWork W112590946 @default.
• W2039232242 hasRelatedWork W149867241 @default.
• W2039232242 hasRelatedWork W2002879234 @default.
• W2039232242 hasRelatedWork W2014570142 @default.
• W2039232242 hasRelatedWork W2039232242 @default.
• W2039232242 hasRelatedWork W2044089871 @default.
• W2039232242 hasRelatedWork W2093518518 @default.
• W2039232242 hasRelatedWork W2095648336 @default.
• W2039232242 hasRelatedWork W2318982351 @default.
• W2039232242 hasRelatedWork W2519267034 @default.
• W2039232242 hasVolume "88" @default.
• W2039232242 isParatext "false" @default.

• next