FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039257059> ?p ?o ?g. }

• W2039257059 endingPage "64" @default.
• W2039257059 startingPage "60" @default.
• W2039257059 abstract "Hepatocellular carcinoma (HCC) is a very common and highly malignant tumor, associated mainly with chronic viral hepatitis, cirrhosis of any cause, aflatoxin exposure and ethanol consumption. The aim of this study was to map genomic aberrations in HCC by a recently developed technique: comparative genomic hybridization (CGH). We applied CGH on 17 liver specimens, of which seven were HCCs. The rest were benign liver tumors, cirrhotic and normal livers, and other liver malignancies. Our study included mainly large tumors (mean size 10.5 cm) unrelated to viral hepatitis or cirrhosis. Our CGH analysis detected genomic imbalances in 42% of HCCs. The common aberrations included DNA gains of 1q, 9p, and 8q and DNA losses of 17p, 13q, 9q, 4q, and 11q. Also, we detected trisomies 8, 9, 18 and 21, which have not been reported previously. Gains and losses of DNA found in this study probably involve oncogenes and tumor suppressor genes that play a role in the puzzle of hepatocarcinogenesis. This study also suggests a possible link between the size of the tumor and the burden of genetic changes." @default.
• W2039257059 created "2016-06-24" @default.
• W2039257059 creator A5014023450 @default.
• W2039257059 creator A5026658735 @default.
• W2039257059 creator A5039875806 @default.
• W2039257059 creator A5049949933 @default.
• W2039257059 creator A5051972218 @default.
• W2039257059 creator A5068404015 @default.
• W2039257059 creator A5070574102 @default.
• W2039257059 creator A5076333833 @default.
• W2039257059 date "2001-11-01" @default.
• W2039257059 modified "2023-09-26" @default.
• W2039257059 title "Analysis of chromosomal aberrations in large hepatocellular carcinomas by comparative genomic hybridization" @default.
• W2039257059 cites W1965008304 @default.
• W2039257059 cites W1968046362 @default.
• W2039257059 cites W1968056868 @default.
• W2039257059 cites W1988995126 @default.
• W2039257059 cites W2009752621 @default.
• W2039257059 cites W2010302945 @default.
• W2039257059 cites W2014170738 @default.
• W2039257059 cites W2016293879 @default.
• W2039257059 cites W2029327959 @default.
• W2039257059 cites W2051020846 @default.
• W2039257059 cites W2052188702 @default.
• W2039257059 cites W2076496963 @default.
• W2039257059 cites W2077275666 @default.
• W2039257059 cites W2084268608 @default.
• W2039257059 cites W2094957661 @default.
• W2039257059 cites W2104475038 @default.
• W2039257059 cites W2109177601 @default.
• W2039257059 cites W2115810916 @default.
• W2039257059 cites W2128573905 @default.
• W2039257059 cites W2136786699 @default.
• W2039257059 cites W2151530333 @default.
• W2039257059 cites W2162912407 @default.
• W2039257059 cites W2166429460 @default.
• W2039257059 cites W2199170296 @default.
• W2039257059 cites W2316593290 @default.
• W2039257059 cites W2917427369 @default.
• W2039257059 cites W3027987826 @default.
• W2039257059 cites W4232272304 @default.
• W2039257059 cites W4376468651 @default.
• W2039257059 doi "https://doi.org/10.1016/s0165-4608(01)00492-7" @default.
• W2039257059 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11734320" @default.
• W2039257059 hasPublicationYear "2001" @default.
• W2039257059 type Work @default.
• W2039257059 sameAs 2039257059 @default.
• W2039257059 citedByCount "18" @default.
• W2039257059 countsByYear W20392570592015 @default.
• W2039257059 crossrefType "journal-article" @default.
• W2039257059 hasAuthorship W2039257059A5014023450 @default.
• W2039257059 hasAuthorship W2039257059A5026658735 @default.
• W2039257059 hasAuthorship W2039257059A5039875806 @default.
• W2039257059 hasAuthorship W2039257059A5049949933 @default.
• W2039257059 hasAuthorship W2039257059A5051972218 @default.
• W2039257059 hasAuthorship W2039257059A5068404015 @default.
• W2039257059 hasAuthorship W2039257059A5070574102 @default.
• W2039257059 hasAuthorship W2039257059A5076333833 @default.
• W2039257059 hasConcept C104317684 @default.
• W2039257059 hasConcept C124942203 @default.
• W2039257059 hasConcept C126322002 @default.
• W2039257059 hasConcept C141231307 @default.
• W2039257059 hasConcept C142724271 @default.
• W2039257059 hasConcept C2776231280 @default.
• W2039257059 hasConcept C2777214474 @default.
• W2039257059 hasConcept C2777575235 @default.
• W2039257059 hasConcept C2778019345 @default.
• W2039257059 hasConcept C2779314089 @default.
• W2039257059 hasConcept C2780732942 @default.
• W2039257059 hasConcept C502942594 @default.
• W2039257059 hasConcept C54355233 @default.
• W2039257059 hasConcept C71924100 @default.
• W2039257059 hasConcept C86803240 @default.
• W2039257059 hasConceptScore W2039257059C104317684 @default.
• W2039257059 hasConceptScore W2039257059C124942203 @default.
• W2039257059 hasConceptScore W2039257059C126322002 @default.
• W2039257059 hasConceptScore W2039257059C141231307 @default.
• W2039257059 hasConceptScore W2039257059C142724271 @default.
• W2039257059 hasConceptScore W2039257059C2776231280 @default.
• W2039257059 hasConceptScore W2039257059C2777214474 @default.
• W2039257059 hasConceptScore W2039257059C2777575235 @default.
• W2039257059 hasConceptScore W2039257059C2778019345 @default.
• W2039257059 hasConceptScore W2039257059C2779314089 @default.
• W2039257059 hasConceptScore W2039257059C2780732942 @default.
• W2039257059 hasConceptScore W2039257059C502942594 @default.
• W2039257059 hasConceptScore W2039257059C54355233 @default.
• W2039257059 hasConceptScore W2039257059C71924100 @default.
• W2039257059 hasConceptScore W2039257059C86803240 @default.
• W2039257059 hasIssue "1" @default.
• W2039257059 hasLocation W20392570591 @default.
• W2039257059 hasLocation W20392570592 @default.
• W2039257059 hasOpenAccess W2039257059 @default.
• W2039257059 hasPrimaryLocation W20392570591 @default.
• W2039257059 hasRelatedWork W1565556347 @default.
• W2039257059 hasRelatedWork W2076689282 @default.
• W2039257059 hasRelatedWork W2091858000 @default.
• W2039257059 hasRelatedWork W2355693500 @default.
• W2039257059 hasRelatedWork W2367089279 @default.

• next