Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039264210> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2039264210 abstract "Background Successful resection of malignant skull base disease depends implicitly on the ability to reconstruct the resulting defects in the craniovisceral diaphragm, to support neural structures, and to prevent ascending intracranial infections. Microsurgery reliably achieves these objectives and has increased the scope of curative oncologic surgery. The authors assessed the reconstructive results and the long-term oncologic outcome of patients having skull base surgery with free tissue transfer. Methods A retrospective review of cases between 1989 and 2001 was undertaken. Demographics, histology, surgical management, complications, locoregional control, and survival were analyzed. Results Predominantly male patients (n = 53; 62 percent) with an average age of 60 years had microvascular reconstruction following oncologic surgery. There was a preponderance of cutaneous malignancies (56 percent), and most lesions involved the anterior skull base (53 percent). Tumors were mostly resected with a combined intracranial or extracranial approach, and reconstruction was undertaken with radial forearm, rectus abdominis, or latissimus dorsi flaps with 94 percent success. Complications occurred in 23 percent of patients, and no specific risk factors for developing intracranial complications were identified. Specifically, extensive reconstructions did not increase the complication rate. The 5-year locoregional control and survival rates were 74 percent and 60 percent, respectively. A positive resection margin significantly increased the risk of locoregional recurrence and worsened disease-specific survival on Cox regression. Survival was also influenced by grade of malignancy. Conclusions Microsurgery is highly reliable for reconstructing defects resulting from oncologic resections of the cranial base. It can and should be undertaken using a small number of highly dependable flaps." @default.
- W2039264210 created "2016-06-24" @default.
- W2039264210 creator A5001696500 @default.
- W2039264210 creator A5002581018 @default.
- W2039264210 creator A5023753168 @default.
- W2039264210 creator A5029185340 @default.
- W2039264210 creator A5049206515 @default.
- W2039264210 creator A5078954385 @default.
- W2039264210 date "2006-10-01" @default.
- W2039264210 modified "2023-09-23" @default.
- W2039264210 title "Long-Term Outcome of Skull Base Surgery with Microvascular Reconstruction for Malignant Disease" @default.
- W2039264210 cites W1972845958 @default.
- W2039264210 cites W1973538192 @default.
- W2039264210 cites W1975073913 @default.
- W2039264210 cites W1988602558 @default.
- W2039264210 cites W1995581874 @default.
- W2039264210 cites W1998767324 @default.
- W2039264210 cites W2035054472 @default.
- W2039264210 cites W2036557528 @default.
- W2039264210 cites W2042254267 @default.
- W2039264210 cites W2046528553 @default.
- W2039264210 cites W2050772767 @default.
- W2039264210 cites W2055241708 @default.
- W2039264210 cites W2065796796 @default.
- W2039264210 cites W2067434161 @default.
- W2039264210 cites W2070013621 @default.
- W2039264210 cites W2082176120 @default.
- W2039264210 cites W2085272420 @default.
- W2039264210 cites W2087792153 @default.
- W2039264210 cites W2097432487 @default.
- W2039264210 cites W2103647854 @default.
- W2039264210 cites W2104392581 @default.
- W2039264210 cites W2135968692 @default.
- W2039264210 cites W2143097098 @default.
- W2039264210 cites W2159535638 @default.
- W2039264210 cites W2321298032 @default.
- W2039264210 cites W2418880401 @default.
- W2039264210 cites W4233086201 @default.
- W2039264210 cites W4252094856 @default.
- W2039264210 cites W4301895484 @default.
- W2039264210 doi "https://doi.org/10.1097/01.prs.0000236895.28858.4a" @default.
- W2039264210 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17016183" @default.
- W2039264210 hasPublicationYear "2006" @default.
- W2039264210 type Work @default.
- W2039264210 sameAs 2039264210 @default.
- W2039264210 citedByCount "16" @default.
- W2039264210 countsByYear W20392642102012 @default.
- W2039264210 countsByYear W20392642102013 @default.
- W2039264210 countsByYear W20392642102014 @default.
- W2039264210 countsByYear W20392642102016 @default.
- W2039264210 countsByYear W20392642102021 @default.
- W2039264210 crossrefType "journal-article" @default.
- W2039264210 hasAuthorship W2039264210A5001696500 @default.
- W2039264210 hasAuthorship W2039264210A5002581018 @default.
- W2039264210 hasAuthorship W2039264210A5023753168 @default.
- W2039264210 hasAuthorship W2039264210A5029185340 @default.
- W2039264210 hasAuthorship W2039264210A5049206515 @default.
- W2039264210 hasAuthorship W2039264210A5078954385 @default.
- W2039264210 hasConcept C126322002 @default.
- W2039264210 hasConcept C141071460 @default.
- W2039264210 hasConcept C167135981 @default.
- W2039264210 hasConcept C2779300802 @default.
- W2039264210 hasConcept C2779399171 @default.
- W2039264210 hasConcept C2781437307 @default.
- W2039264210 hasConcept C71924100 @default.
- W2039264210 hasConcept C81182388 @default.
- W2039264210 hasConceptScore W2039264210C126322002 @default.
- W2039264210 hasConceptScore W2039264210C141071460 @default.
- W2039264210 hasConceptScore W2039264210C167135981 @default.
- W2039264210 hasConceptScore W2039264210C2779300802 @default.
- W2039264210 hasConceptScore W2039264210C2779399171 @default.
- W2039264210 hasConceptScore W2039264210C2781437307 @default.
- W2039264210 hasConceptScore W2039264210C71924100 @default.
- W2039264210 hasConceptScore W2039264210C81182388 @default.
- W2039264210 hasLocation W20392642101 @default.
- W2039264210 hasOpenAccess W2039264210 @default.
- W2039264210 hasPrimaryLocation W20392642101 @default.
- W2039264210 hasRelatedWork W2003938723 @default.
- W2039264210 hasRelatedWork W2047967234 @default.
- W2039264210 hasRelatedWork W2118496982 @default.
- W2039264210 hasRelatedWork W2364998975 @default.
- W2039264210 hasRelatedWork W2369162477 @default.
- W2039264210 hasRelatedWork W2439875401 @default.
- W2039264210 hasRelatedWork W4238867864 @default.
- W2039264210 hasRelatedWork W4240094682 @default.
- W2039264210 hasRelatedWork W2519357708 @default.
- W2039264210 hasRelatedWork W2525756941 @default.
- W2039264210 isParatext "false" @default.
- W2039264210 isRetracted "false" @default.
- W2039264210 magId "2039264210" @default.
- W2039264210 workType "article" @default.