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- W2039291749 abstract "The subcutaneous administration of a single dose of angiotensin to pregnant hamsters on the eighth day of gestation produced developmental anomalies of the cranium, brain and viscera. Edematous areas along the spinal axis were observed. The number of dead, resorbed and runt fetuses in the experimental litters was increased markedly over the number observed in control litters. The mechanism of action of angiotensin in the present study is postulated to include one or all of the following: (1) decrease in uterine blood flow by direct action on uterine smooth muscles and blood vessels; (2) release of catecholamines from adrenal gland, and their action on uterine smooth muscle and blood vessels; (3) imbalance of normal mitosis in fetus by the catecholamines released by angiotensin. Comparative studies using trypan blue were carried out simultaneously." @default.
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- W2039291749 date "1969-05-01" @default.
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- W2039291749 title "Angiotensin teratogenicity in the fetal hamster" @default.
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- W2039291749 doi "https://doi.org/10.1016/0024-3205(69)90447-0" @default.
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