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• W2039311903 abstract "The lignan 8,8'-bis-(methylenedioxy)cinnamic acid (BMDCA) is a powerful competitive inhibitor (K1 = 2.0 microM) of the lignin peroxidase (LiP) from Phanerochaete chrysosporium and of the extracellular peroxidase of Phlebia radiata (I0.5 = 10 microM). BMDCA derivatives with the same double bond system also inhibited these enzymes to some extent. If the double bonds were hydrogenated, the inhibitory effect was lost. HRP-VIII and HRP-XI were slightly inhibited by BMDCA (I0.5 > 50 microM) and two plant peroxidases described as efficient lignan synthesizers were unaffected. Liquid cultures of P chrysosporium did not discolour the dve Poly R478 when 250 microM of BMDCA was present." @default.
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• W2039311903 date "1995-01-01" @default.
• W2039311903 modified "2023-09-26" @default.
• W2039311903 title "Lignan models as inhibitors of Phanerochaete chrysosporium lignin peroxidase" @default.
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• W2039311903 doi "https://doi.org/10.1016/0300-9084(96)88186-7" @default.
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